Longitudinal Prospective MRI studies of Brain Morphology in Patients with Schizophrenia and Bipolar Disorder - Genetic Variation and Etiological Risk
- Prosjektnummer
- 2008011
- Ansvarlig person
- Ingrid Agartz
- Institusjon
- Diakonhjemmet Sykehus AS
- Prosjektkategori
- Postdoktorstipend
- Helsekategori
- Mental Health
- Forskningsaktivitet
- 2. Aetiology
A 5-year follow-up study of brain cortical and subcortical abnormalities in a schizophrenia cohort.
Schizophr Res 2012 Dec;142(1-3):209-16. Epub 2012 okt 30
PMID: 23116883
Cortical volume, surface area, and thickness in schizophrenia and bipolar disorder.
Biol Psychiatry 2012 Mar;71(6):552-60. Epub 2012 jan 26
PMID: 22281121
Cortical folding in Broca's area relates to obstetric complications in schizophrenia patients and healthy controls.
Psychol Med 2012 Jun;42(6):1329-37. Epub 2011 okt 26
PMID: 22029970
Comprehensive segmentation of subcortical brain volumes in early onset schizophrenia reveals limited structural abnormalities.
Psychiatry Res 2012 Jul;203(1):14-23. Epub 2012 aug 21
PMID: 22917502
TCF4 sequence variants and mRNA levels are associated with neurodevelopmental characteristics in psychotic disorders.
Transl Psychiatry 2012;2():e112. Epub 2012 mai 8
PMID: 22832956
Effect of DISC1 SNPs on brain structure in healthy controls and patients with a history of psychosis.
Am J Med Genet B Neuropsychiatr Genet 2012 Sep;159B(6):722-30. Epub 2012 jul 19
PMID: 22815203
Neurocognitive function in long-term treated schizophrenia: a five-year follow-up study.
Psychiatry Res 2012 Dec;200(2-3):144-52. Epub 2012 mai 30
PMID: 22657952
Brain cortical thickness and surface area correlates of neurocognitive performance in patients with schizophrenia, bipolar disorder, and healthy adults.
J Int Neuropsychol Soc 2011 Nov;17(6):1080-93. Epub 2011 okt 3
PMID: 22013998
Association of genetic variants on 15q12 with cortical thickness and cognition in schizophrenia.
Arch Gen Psychiatry 2011 Aug;68(8):781-90.
PMID: 21810643
Common sequence variants in the major histocompatibility complex region associate with cerebral ventricular size in schizophrenia.
Biol Psychiatry 2011 Oct;70(7):696-8. Epub 2011 apr 22
PMID: 21514568
Candidate gene analysis of the human natural killer-1 carbohydrate pathway and perineuronal nets in schizophrenia: B3GAT2 is associated with disease risk and cortical surface area.
Biol Psychiatry 2011 Jan;69(1):90-6. Epub 2010 okt 15
PMID: 20950796
Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: A combined analysis of independent samples.
Am J Med Genet B Neuropsychiatr Genet 2011 Jan. Epub 2011 jan 13
PMID: 21234904
Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: a combined analysis of independent samples.
Am J Med Genet B Neuropsychiatr Genet 2011 Mar;156(2):215-24. Epub 2011 jan 13
PMID: 21302350
Genome-wide study identifies PTPRO and WDR72 and FOXQ1-SUMO1P1 interaction associated with neurocognitive function.
J Psychiatr Res 2012 Feb;46(2):271-8. Epub 2011 nov 29
PMID: 22126837
Lack of association between the regulator of G-protein signaling 4 (RGS4) rs951436 polymorphism and schizophrenia.
Psychiatr Genet 2012 Oct;22(5):263-4.
PMID: 22157635
Association analysis of ANK3 gene variants in nordic bipolar disorder and schizophrenia case-control samples.
Am J Med Genet B Neuropsychiatr Genet 2011 Dec;156B(8):969-74. Epub 2011 okt 3
PMID: 21972176
Affective symptoms are associated with markers of inflammation and immune activation in bipolar disorders but not in schizophrenia.
J Psychiatr Res 2011 Dec;45(12):1608-16. Epub 2011 sep 1
PMID: 21889167
Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe.
Mol Psychiatry 2012 Sep;17(9):906-17. Epub 2011 jul 12
PMID: 21747397
Lack of association between two dopamine D2 receptor gene polymorphisms and schizophrenia.
Psychiatr Genet 2011 Aug;21(4):214-5.
PMID: 21712758
The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia.
Biol Psychiatry 2011 Jul;70(1):35-42. Epub 2011 mar 24
PMID: 21439553
Kynurenine 3-monooxygenase (KMO) polymorphisms in schizophrenia: an association study.
Schizophr Res 2011 Apr;127(1-3):270-2. Epub 2010 okt 27
PMID: 21030213
Association analysis of PALB2 and BRCA2 in bipolar disorder and schizophrenia in a scandinavian case-control sample.
Am J Med Genet B Neuropsychiatr Genet 2010 Oct;153B(7):1276-82.
PMID: 20872766
SRD5A2 is associated with increased cortisol metabolism in schizophrenia spectrum disorders.
Prog Neuropsychopharmacol Biol Psychiatry 2010 Dec;34(8):1500-6. Epub 2010 aug 25
PMID: 20800085
Suicidality in first episode psychosis is associated with insight and negative beliefs about psychosis.
Schizophr Res 2010 Nov;123(2-3):257-62. Epub 2010 aug 3
PMID: 20685083
An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes.
Prog Neuropsychopharmacol Biol Psychiatry 2010 Oct;34(7):1259-65. Epub 2010 jul 16
PMID: 20638435
Cortical thickness and subcortical volumes in schizophrenia and bipolar disorder.
Biol Psychiatry 2010 Jul;68(1):41-50.
PMID: 20609836
Catechol O-methyltransferase variants and cognitive performance in schizophrenia and bipolar disorder versus controls.
Schizophr Res 2010 Sep;122(1-3):31-7. Epub 2010 jun 1
PMID: 20605701
Tryptophan hydroxylase gene 1 (TPH1) variants associated with cerebrospinal fluid 5-hydroxyindole acetic acid and homovanillic acid concentrations in healthy volunteers.
Psychiatry Res 2010 Dec;180(2-3):63-7. Epub 2010 mai 23
PMID: 20580984
Osteoprotegerin levels in patients with severe mental disorders.
J Psychiatry Neurosci 2010 Sep;35(5):304-10.
PMID: 20569643
Amphetamine dependence and co-morbid alcohol abuse: associations to brain cortical thickness.
BMC Pharmacol 2010;10():5. Epub 2010 mai 20
PMID: 20487539
Investigating relationships between cortical thickness and cognitive performance in patients with schizophrenia and healthy adults.
Psychiatry Res 2010 May;182(2):123-33. Epub 2010 apr 24
PMID: 20456929
A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample.
J Affect Disord 2010 Oct;126(1-2):312-6. Epub 2010 mai 7
PMID: 20451256
No effect of obstetric complications on basal ganglia volumes in schizophrenia.
Prog Neuropsychopharmacol Biol Psychiatry 2010 May;34(4):619-23. Epub 2010 mar 1
PMID: 20193725
Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort.
J Psychiatr Res 2010 Sep;44(12):748-53. Epub 2010 feb 24
PMID: 20185149
Excessive substance use in bipolar disorder is associated with impaired functioning rather than clinical characteristics, a descriptive study.
BMC Psychiatry 2010;10():9. Epub 2010 jan 27
PMID: 20105311
Sex-dependent association of common variants of microcephaly genes with brain structure.
Proc Natl Acad Sci U S A 2010 Jan;107(1):384-8. Epub 2009 des 22
PMID: 20080800
Association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and age of onset in schizophrenia.
Am J Med Genet B Neuropsychiatr Genet 2010 Mar;153B(2):610-8.
PMID: 19746410
A common MECP2 haplotype associates with reduced cortical surface area in humans in two independent populations.
Proc Natl Acad Sci U S A 2009 Sep;106(36):15483-8. Epub 2009 aug 26
PMID: 19717458
Minute effects of sex on the aging brain: a multisample magnetic resonance imaging study of healthy aging and Alzheimer's disease.
J Neurosci 2009 Jul;29(27):8774-83.
PMID: 19587284
The tryptophan hydroxylase 1 (TPH1) gene, schizophrenia susceptibility, and suicidal behavior: a multi-centre case-control study and meta-analysis.
Am J Med Genet B Neuropsychiatr Genet 2010 Mar;153B(2):387-96.
PMID: 19526457
Tyrosine hydroxylase Val81Met polymorphism: lack of association with schizophrenia.
Psychiatr Genet 2009 Oct;19(5):273-4.
PMID: 19491717
Cerebral cortical thickness and a history of obstetric complications in schizophrenia.
J Psychiatr Res 2009 Dec;43(16):1287-93. Epub 2009 mai 26
PMID: 19473666
DTNBP1, NRG1, DAOA, DAO and GRM3 polymorphisms and schizophrenia: an association study.
Neuropsychobiology 2009;59(3):142-50. Epub 2009 mai 12
PMID: 19439994
Evidence for a possible association of neurotrophin receptor (NTRK-3) gene polymorphisms with hippocampal function and schizophrenia.
Neurobiol Dis 2009 Jun;34(3):518-24. Epub 2009 mar 31
PMID: 19344762
Landmark-based software for anatomical measurements: a precision study.
Clin Anat 2009 May;22(4):456-62.
PMID: 19306317
Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE).
Psychiatry Res 2009 Aug;168(3):256-8. Epub 2009 feb 15
PMID: 19223264
High consistency of regional cortical thinning in aging across multiple samples.
Cereb Cortex 2009 Sep;19(9):2001-12. Epub 2009 jan 15
PMID: 19150922
A possible association between schizophrenia and GRIK3 polymorphisms in a multicenter sample of Scandinavian origin (SCOPE).
Schizophr Res 2009 Feb;107(2-3):242-8. Epub 2008 nov 20
PMID: 19022628
Grey and white matter proportional relationships in the cerebellar vermis altered in schizophrenia.
Cerebellum 2009 Mar;8(1):52-60.
PMID: 18972181
Local and covariate-modulated false discovery rates applied in neuroimaging.
Neuroimage 2009 Aug;47(1):213-9. Epub 2009 mar 31
PMID: 19341802
The relationship between symptom severity and regional cortical and grey matter volumes in schizophrenia.
Prog Neuropsychopharmacol Biol Psychiatry 2009 Apr;33(3):482-90. Epub 2009 feb 4
PMID: 19439246
Consistent neuroanatomical age-related volume differences across multiple samples.
Neurobiol Aging 2011 May;32(5):916-32. Epub 2009 jun 30
PMID: 19570593
Increased sensitivity to effects of normal aging and Alzheimer's disease on cortical thickness by adjustment for local variability in gray/white contrast: a multi-sample MRI study.
Neuroimage 2009 Oct;47(4):1545-57. Epub 2009 jun 6
PMID: 19501655
Investigating possible subtypes of schizophrenia patients and controls based on brain cortical thickness.
Psychiatry Res 2008 Dec;164(3):254-64.
PMID: 19022629
Association between a disrupted-in-schizophrenia 1 (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample.
Schizophr Res 2008 Dec;106(2-3):237-41. Epub 2008 sep 24
PMID: 18818052
Brain-derived neurotrophic factor gene variation influences cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol concentrations in healthy volunteers.
J Neural Transm 2008 Dec;115(12):1695-9. Epub 2008 sep 10
PMID: 18781277
Brain-derived neurotrophic factor polymorphisms and frontal cortex morphology in schizophrenia.
Psychiatr Genet 2008 Aug;18(4):177-83.
PMID: 18628679
Craniofacial dysmorphology and cortical thickness in men with schizophrenia.
Schizophr Res 2008 Aug;103(1-3):322-3. Epub 2008 mai 23
PMID: 18501563
The estrogen hypothesis of schizophrenia implicates glucose metabolism: association study in three independent samples.
BMC Med Genet 2008;9():39. Epub 2008 mai 6
PMID: 18460190
Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene.
Am J Med Genet B Neuropsychiatr Genet 2008 Oct;147B(7):1089-100.
PMID: 18384059
Two methylenetetrahydrofolate reductase gene (MTHFR) polymorphisms, schizophrenia and bipolar disorder: an association study.
Am J Med Genet B Neuropsychiatr Genet 2008 Sep;147B(6):976-82.
PMID: 18165967
Assessing apathy: the use of the Apathy Evaluation Scale in first episode psychosis.
Eur Psychiatry 2008 Jan;23(1):33-9. Epub 2007 okt 29
PMID: 18029152
Regional thinning of the cerebral cortex in schizophrenia: effects of diagnosis, age and antipsychotic medication.
Schizophr Res 2008 Jan;98(1-3):16-28. Epub 2007 okt 22
PMID: 17933495
Minor physical anomalies in schizophrenia: is age a confounding factor?
Psychol Med 2008 Jan;38(1):154-6.
PMID: 17640439
Abnormalities of brain morphology: Evidence from MRI studies.
In: Schizophrenia – modern concepts and research findings. Eds H Hall-E Hall. Studentlitteratur, Sverige, 2008, ISBN: 9789144029801
Anatomical brain structure and the relationship with neurocognitive functioning.
- Disputert:
- september 2011
- Hovedveileder:
- Ingrid Agartz
Effects of obstetric complications on brain structure in schizophrenia
- Disputert:
- januar 2011
- Hovedveileder:
- Ingrid Agartz
Machine learning as a statistical tool in schizophrenia research
- Disputert:
- april 2008
- Hovedveileder:
- Ingrid Agartz
Characterization of brain morphology in patients with schizophrenia
- Disputert:
- november 2008
- Hovedveileder:
- Ingrid Agartz
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