Stem cells for tissue engineering of hyaline cartilage
- Prosjektnummer
- 2009069
- Ansvarlig person
- Jan E. Brinchmann
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Doktorgradsstipend
- Helsekategori
- Musculoskeletal
- Forskningsaktivitet
- 5. Treatment Developement
Similar properties of chondrocytes from osteoarthritis joints and mesenchymal stem cells from healthy donors for tissue engineering of articular cartilage.
PLoS One 2013;8(5):e62994. Epub 2013 mai 9
PMID: 23671648 - Inngår i doktorgradsavhandlingen
Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells.
BMC Genomics 2013;14():105. Epub 2013 feb 15
PMID: 23414147 - Inngår i doktorgradsavhandlingen
Chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells in self-gelling alginate discs reveals novel chondrogenic signature gene clusters.
Tissue Eng Part A 2011 Apr;17(7-8):1003-13. Epub 2011 jan 10
PMID: 21087199 - Inngår i doktorgradsavhandlingen
Importance of serum source for the in vitro replicative senescence of human bone marrow derived mesenchymal stem cells.
J Cell Physiol 2011 Nov;226(11):2908-15.
PMID: 21302288
Effect of three-dimensional culture and incubator gas concentration on phenotype and differentiation capability of human mesenchymal stem cells.
J Cell Biochem 2011 Feb;112(2):684-93.
PMID: 21268090
Human primary articular chondrocytes, chondroblasts-like cells, and dedifferentiated chondrocytes: differences in gene, microRNA, and protein expression and phenotype.
Tissue Eng Part C Methods 2011 Feb;17(2):219-27. Epub 2010 okt 21
PMID: 20799885
Effect of three-dimensional culture and incubator gas concentration on phenotype and differentiation capability of human mesenchymal stem cells.
J Cell Biochem 2010 Dec. Epub 2010 des 28
PMID: 21190196
Chondrogenesis in a hyaluronic acid scaffold: comparison between chondrocytes and MSC from bone marrow and adipose tissue.
Knee Surg Sports Traumatol Arthrosc 2010 Oct;18(10):1407-16. Epub 2009 des 18
PMID: 20020100
Mesenchymal stem cell-based therapy for cartilage repair: a review.
Knee Surg Sports Traumatol Arthrosc 2009 Nov;17(11):1289-97. Epub 2009 mar 31
PMID: 19333576
Phenotype and gene expression of human mesenchymal stem cells in alginate scaffolds.
Tissue Eng Part A 2009 Jul;15(7):1763-73.
PMID: 19115828
Modulation of DNA glycosylase activities in mesenchymal stem cells.
Exp Cell Res 2009 Sep;315(15):2558-67. Epub 2009 mai 25
PMID: 19477173
Importance of SOX8 for in vitro chondrogenic differentiation of human mesenchymal stromal cells
Stem Cells, 2014, in press
Tissue engineering of hyaline cartilage. Genome-wide investigation of molecular mechanisms during in vitro chondrogenesis
- Disputert:
- september 2013
- Hovedveileder:
- Jan E. Brinchmann
Human mesenchymal stem cells. Culture conditions, genomic and epigenetic stability and senescence
- Disputert:
- desember 2010
- Hovedveileder:
- Jan E. Brinchmann
- Tommy Aleksander Karlsen Postdoktorstipendiat
- Amilton Fernandes Prosjektdeltaker
- Jan Christian Bryne Postdoktorstipendiat
- Leonardo Andrés Meza-Zepeda Prosjektdeltaker
- Philippe Collas Prosjektdeltaker
- Tarjei Mikkelsen Prosjektdeltaker
- Axel Küchler Postdoktorstipendiat
- Jan E. Brinchmann Prosjektleder
- Sarah R Herlofsen Doktorgradsstipendiat
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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