Chromatin defects in stem cells in the context of nuclear envelope-linked diseases
- Prosjektnummer
- 2009089
- Ansvarlig person
- Phillippe Collas
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Postdoktorstipend
- Helsekategori
- Generic Health Relevance
- Forskningsaktivitet
- 1. Underpinning
A chromatin immunoprecipitation protocol for small cell numbers.
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Prepatterning of developmental gene expression by modified histones before zygotic genome activation.
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Remodeling of ribosomal genes in somatic cells by Xenopus egg extract.
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Protein phosphatase 1 regulators in DNA damage signaling.
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cAMP induces autophagy via a novel pathway involving ERK, cyclin E and Beclin 1.
Autophagy 2011 Oct;7(10):1199-211. Epub 2011 okt 1
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Chromatin environment of histone variant H3.3 revealed by quantitative imaging and genome-scale chromatin and DNA immunoprecipitation.
Mol Biol Cell 2010 Jun;21(11):1872-84. Epub 2010 apr 7
PMID: 20375147
Promoter DNA methylation patterns of differentiated cells are largely programmed at the progenitor stage.
Mol Biol Cell 2010 Jun;21(12):2066-77. Epub 2010 apr 21
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Programming differentiation potential in mesenchymal stem cells.
Epigenetics 2010 Aug;5(6):476-82. Epub 2010 aug 16
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The current state of chromatin immunoprecipitation.
Mol Biotechnol 2010 May;45(1):87-100.
PMID: 20077036
Epigenetic states in stem cells.
Biochim Biophys Acta 2009 Sep;1790(9):900-5. Epub 2008 okt 25
PMID: 19013220
Fast genomic muChIP-chip from 1,000 cells.
Genome Biol 2009;10(2):R13. Epub 2009 feb 10
PMID: 19208222
The state-of-the-art of chromatin immunoprecipitation.
Methods Mol Biol 2009;567():1-25.
PMID: 19588082
MicroChIP: chromatin immunoprecipitation for small cell numbers.
Methods Mol Biol 2009;567():59-74.
PMID: 19588085
Immunoprecipitation of methylated DNA.
Methods Mol Biol 2009;567():249-62.
PMID: 19588097
Lineage-specific promoter DNA methylation patterns segregate adult progenitor cell types.
Stem Cells Dev 2010 Aug;19(8):1257-66.
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Histone H3 modifications associated with differentiation and long-term culture of mesenchymal adipose stem cells.
Stem Cells Dev 2009 Jun;18(5):725-36.
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Histone variant H3.3 transits through PML bodies before incorporation into chromatin
EMBO Conference Series 2011
Epigenetic landscape of pluripotency-assocated genes in human cells
- Disputert:
- januar 2011
- Hovedveileder:
- Philippe Collas
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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