Cancer cell migration and metastasis
- Prosjektnummer
- 2010015
- Ansvarlig person
- Jørgen Wesche
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Forskerstipend
- Helsekategori
- Cancer
- Forskningsaktivitet
- 1. Underpinning
PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1.
Biochem J 2014 Aug 1;461(3):383-90.
PMID: 24840251
Photoactivation approaches reveal a role for Rab11 in FGFR4 recycling and signalling.
Traffic 2014 Jun;15(6):665-83. Epub 2014 mar 31
PMID: 24589086
Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration.
EMBO Rep 2013 Jan;14(1):57-64. Epub 2012 nov 16
PMID: 23154468
ERK-mediated phosphorylation of fibroblast growth factor receptor 1 on Ser777 inhibits signaling.
Sci Signal 2013 Feb 12;6(262):ra11. Epub 2013 feb 12
PMID: 23405013
RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789.
Oncogene 2013 Oct 21. Epub 2013 okt 21
PMID: 24141780
Phosphatidylinositol 5-phosphate is a second messenger important for cell migration.
Commun Integr Biol 2013 Sep 1;6(5):e25446. Epub 2013 jun 28
PMID: 24265857
Fibroblast growth factors and their receptors in cancer.
Biochem J 2011 Jul;437(2):199-213.
PMID: 21711248
Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling.
PLoS One 2011;6(7):e21708. Epub 2011 jul 14
PMID: 21779335
Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes.
Dev Cell 2010 Jul;19(1):148-59.
PMID: 20643357
Roles of fibroblast growth factor receptors in carcinogenesis.
Mol Cancer Res 2010 Nov;8(11):1439-52. Epub 2010 okt 13
PMID: 21047773
- Ellen Margrethe Haugsten Prosjektdeltaker
- Jørgen Wesche Prosjektleder
- Angela Oppelt Doktorgradsstipendiat
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til eRapport