Protracted gluten antigen presentation as key factor for development of celiac disease
- Prosjektnummer
- 2010048
- Ansvarlig person
- Ludvig M. Sollid
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Postdoktorstipend
- Helsekategori
- Inflammatory and Immune System
- Forskningsaktivitet
- 2. Aetiology
Epitope-dependent Functional Effects of Celiac Disease Autoantibodies on Transglutaminase 2.
J Biol Chem 2016 Dec 02;291(49):25542-25552. Epub 2016 okt 26
PMID: 27784785
Multivalent pIX phage display selects for distinct and improved antibody properties.
Sci Rep 2016 Dec 14;6():39066. Epub 2016 des 14
PMID: 27966617
T-cell and B-cell immunity in celiac disease.
Best Pract Res Clin Gastroenterol 2015 Jun;29(3):413-23. Epub 2015 mai 7
PMID: 26060106
Enhanced B-Cell Receptor Recognition of the Autoantigen Transglutaminase 2 by Efficient Catalytic Self-Multimerization.
PLoS One 2015;10(8):e0134922. Epub 2015 aug 5
PMID: 26244572
Igs as Substrates for Transglutaminase 2: Implications for Autoantibody Production in Celiac Disease.
J Immunol 2015 Dec 1;195(11):5159-68. Epub 2015 okt 26
PMID: 26503953
Small bowel, celiac disease and adaptive immunity.
Dig Dis 2015;33(2):115-21. Epub 2015 apr 22
PMID: 25925911
Triggers and drivers of autoimmunity: lessons from coeliac disease.
Nat Rev Immunol 2013 Apr;13(4):294-302. Epub 2013 mar 15
PMID: 23493116
Posttranslational modification of gluten shapes TCR usage in celiac disease.
J Immunol 2011 Sep;187(6):3064-71. Epub 2011 aug 17
PMID: 21849672
Celiac disease and transglutaminase 2: a model for posttranslational modification of antigens and HLA association in the pathogenesis of autoimmune disorders.
Curr Opin Immunol 2011 Dec;23(6):732-8. Epub 2011 sep 12
PMID: 21917438
T-cell response to gluten in patients with HLA-DQ2.2 reveals requirement of peptide-MHC stability in celiac disease.
Gastroenterology 2012 Mar;142(3):552-61. Epub 2011 nov 19
PMID: 22108197
Tolerance to ingested deamidated gliadin in mice is maintained by splenic, type 1 regulatory T cells.
Gastroenterology 2011 Aug;141(2):610-20, 620.e1-2. Epub 2011 apr 28
PMID: 21683079
Integration of genetic and immunological insights into a model of celiac disease pathogenesis.
Annu Rev Immunol 2011 Apr;29():493-525.
PMID: 21219178
- Fleur du Pré Postdoktorstipendiat (finansiert av denne bevilgning)
- Shuo-Wang Qiao Prosjektdeltaker
- Ludvig Magne Sollid Prosjektleder
- Fleur Du Pre Postdoktorstipendiat
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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