Screening for PI3P effectors important for cytokinesis and tumor suppression
- Prosjektnummer
- 2010054
- Ansvarlig person
- Camilla Raiborg
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Forskerstilling
- Helsekategori
- Cancer
- Forskningsaktivitet
- 1. Underpinning
Class III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane traffic.
FEBS J 2013 Jun;280(12):2730-42. Epub 2013 feb 6
PMID: 23289851
Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation.
J Cell Biol 2013 Jul 22;202(2):331-49.
PMID: 23878278
Phosphatidylinositol 3-phosphate, a lipid that regulates membrane dynamics, protein sorting and cell signalling.
Bioessays 2013 Oct;35(10):900-12. Epub 2013 jul 24
PMID: 23881848
The PtdIns3P-binding protein Phafin 2 mediates epidermal growth factor receptor degradation by promoting endosome fusion.
Traffic 2012 Nov;13(11):1547-63. Epub 2012 aug 8
PMID: 22816767
SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis.
Oncogene 2011 Sep;30(37):3967-78. Epub 2011 apr 18
PMID: 21499309
Cell biology. A helix for the final cut.
Science 2011 Mar;331(6024):1533-4.
PMID: 21436431
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody.
Nat Cell Biol 2010 Apr;12(4):362-71. Epub 2010 mar 7
PMID: 20208530
- Harald Alfred Stenmark Forskningsgruppeleder
- Camilla Raiborg Prosjektleder
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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