Early mechanisms of allograft fibrosis- role of matricellular proteins and novel cytokines
- Prosjektnummer
- 2011008
- Ansvarlig person
- Monika Kasprzycka
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Forskerstipend
- Helsekategori
- Inflammatory and Immune System
- Forskningsaktivitet
- 1. Underpinning
Interleukin-33 drives a proinflammatory endothelial activation that selectively targets nonquiescent cells.
Arterioscler Thromb Vasc Biol 2013 Feb;33(2):e47-55. Epub 2012 nov 15
PMID: 23162017
The alarmin IL-33 is a notch target in quiescent endothelial cells.
Am J Pathol 2012 Sep;181(3):1099-111. Epub 2012 jul 16
PMID: 22809957
Matricellular proteins tenascin C and periostin are assiciated with kidney allograft fibrosis
Poster presentation at the meeting "Fibrosis from Bench to Bedside" Keystone Symposia, keystone, Colorado, USA 23-28 March 2014
Tenascin-C in kidney fibrosis
Oral presentation at the meeting"TENASCINS: DEFINING THEIR ROLE IN TISSUE HOMEOSTASIS AND CANCER" Strasbourg, France 12-13 may 2014
Tenascins in fibrotic disorders – from bench to bedside
Accepted for publication in Cell Adhesion & Migration.
Tenascin C enhances the proinflammatory response to IL-1 family cytokines ...
submitted to Ametican Journal of Pathology
TnC and POSTN enhance the proinflammatory response in EC
Poser and oral presentation at FASEB conference “MATRICELLULAR PROTEINS IN DEVELOPMENT, HEALTH, AND DISEASE” July 28-August 2, 2013
Tenascin C induced by IL-33 activation feeds back to amplify the effect of alarmins on ICAM1 expression in endothelial cells and
poster at 5th Amsterdam ZOO meeting on ‘Cell Adhesion and Migration in Inflammation and Cancer’ May 11-14 2011
Role of matricellular proteins in cardiac allograft fibrosis
Chapter in "Cardiac Transplantation", ISBN 979-953-307-052-9
Molecular mechanisms of endothelial cell quiescence and proinflammatory activation
- Disputert:
- april 2014
- Hovedveileder:
- Guttorm Haraldsen
Involvment of Notch signaling in quiescence and inflammatory activation of endothelial cells
- Disputert:
- februar 2013
- Hovedveileder:
- Guttorm Haraldsen
- Junbai Wang Prosjektdeltaker
- Francesca Gatti Prosjektdeltaker
- Anna Reisæter Prosjektdeltaker
- Ståle Sund Prosjektdeltaker
- Guttorm Haraldsen Forskningsgruppeleder
- Helge Scott Prosjektdeltaker
- Bjarte Fosby Prosjektdeltaker
- Clara Hammarstrøm Doktorgradsstipendiat
- Eirik Sundlisæter Doktorgradsstipendiat
- Johanna Hol Postdoktorstipendiat
- Nadine Frerker Postdoktorstipendiat
- Clara Louise Hammarstrøm Doktorgradsstipendiat
- Monika Kasprzycka Forsker (annen finansiering)
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til eRapport