Membrane dynamics and cancer
- Prosjektnummer
- 2011058
- Ansvarlig person
- Harald Stenmark
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Helse Sør-Øst forskningsgruppe
- Helsekategori
- Cancer
- Forskningsaktivitet
- 1. Underpinning
Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding.
Cell Cycle 2016 Nov;15(21):2943-2957. Epub 2016 sep 13
PMID: 27625181
PIKfyve inhibition increases exosome release and induces secretory autophagy.
Cell Mol Life Sci 2016 Dec;73(24):4717-4737. Epub 2016 jul 20
PMID: 27438886
Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer.
Nat Commun 2016 Jan 12;7():10318. Epub 2016 jan 12
PMID: 26754771
Isolation and mass spectrometry analysis of urinary extraexosomal proteins.
Sci Rep 2016 Nov 02;6():36331. Epub 2016 nov 2
PMID: 27805059
Deciphering the Nongenomic, Mitochondrial Toxicity of Tamoxifens As Determined by Cell Metabolism and Redox Activity.
ACS Chem Biol 2016 Jan 15;11(1):251-62. Epub 2015 nov 30
PMID: 26569462
Antibody Staining in Drosophila Germaria.
Methods Mol Biol 2016;1457():19-33.
PMID: 27557571
Phosphoinositides in Control of Membrane Dynamics.
Annu Rev Cell Dev Biol 2016 Oct 06;32():143-171. Epub 2016 aug 15
PMID: 27576122
Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity.
PLoS One 2016;11(8):e0160507. Epub 2016 aug 2
PMID: 27482906
Plasma membrane repairs by small GTPase Rab3a.
J Cell Biol 2016 Jun 20;213(6):613-5.
PMID: 27325788
Arv1 promotes cell division by recruiting IQGAP1 and myosin to the cleavage furrow.
Cell Cycle 2016;15(5):628-43.
PMID: 27104745
ER-endosome contact sites in endosome positioning and protrusion outgrowth.
Biochem Soc Trans 2016 Apr 15;44(2):441-6.
PMID: 27068952
Phosphoinositides in membrane contact sites.
Biochem Soc Trans 2016 Apr 15;44(2):425-30.
PMID: 27068950
Novel ESCRT functions in cell biology: spiraling out of control?
Curr Opin Cell Biol 2016 Aug;41():1-8. Epub 2016 mar 28
PMID: 27031044
Closing a gap in the nuclear envelope.
Curr Opin Cell Biol 2016 Jun;40():90-7. Epub 2016 mar 24
PMID: 27016712
ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission.
J Cell Biol 2016 Feb 29;212(5):499-513.
PMID: 26929449
ESCRT proteins restrict constitutive NF-?B signaling by trafficking cytokine receptors.
Sci Signal 2016 Jan 19;9(411):ra8. Epub 2016 jan 19
PMID: 26787452
ALIX and ESCRT-III coordinately control cytokinetic abscission during germline stem cell division in vivo.
PLoS Genet 2015 Jan;11(1):e1004904. Epub 2015 jan 30
PMID: 25635693
Repeated ER-endosome contacts promote endosome translocation and neurite outgrowth.
Nature 2015 Apr 9;520(7546):234-8.
PMID: 25855459
Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing.
Nature 2015 Jun 11;522(7555):231-5. Epub 2015 jun 3
PMID: 26040712
Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy.
Autophagy 2015;11(9):1458-70.
PMID: 26207339
Cellular functions of Rab GTPases at a glance.
J Cell Sci 2015 Sep 1;128(17):3171-6. Epub 2015 aug 13
PMID: 26272922
Src64 controls a novel actin network required for proper ring canal formation in the Drosophila male germline.
Development 2015 Dec 1;142(23):4107-18.
PMID: 26628094
SARA and RNF11 at the crossroads of EGFR signaling and trafficking.
Methods Enzymol 2014;535():225-47.
PMID: 24377927
CK2 involvement in ESCRT-III complex phosphorylation.
Arch Biochem Biophys 2014 Mar 1;545():83-91. Epub 2014 jan 15
PMID: 24440309
Association of CHMP4B and autophagy with micronuclei: implications for cataract formation.
Biomed Res Int 2014;2014():974393. Epub 2014 mar 11
PMID: 24741567
ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4.
Nat Cell Biol 2014 Jun;16(6):550-60. Epub 2014 mai 11
PMID: 24814515
An isoprenylation and palmitoylation motif promotes intraluminal vesicle delivery of proteins in cells from distant species.
PLoS One 2014;9(9):e107190. Epub 2014 sep 10
PMID: 25207810
Regulation of the Tumor-Suppressor Function of the Class III Phosphatidylinositol 3-Kinase Complex by Ubiquitin and SUMO.
Cancers (Basel) 2014;7(1):1-29. Epub 2014 des 23
PMID: 25545884
Multiple functions of the SNARE protein Snap29 in autophagy, endocytic, and exocytic trafficking during epithelial formation in Drosophila.
Autophagy 2014 Dec 2;10(12):2251-68.
PMID: 25551675
TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy.
Autophagy 2013 Dec;9(12):1955-64.
PMID: 24128730
Molecular mechanisms of the membrane sculpting ESCRT pathway.
Cold Spring Harb Perspect Biol 2013 Sep;5(9). Epub 2013 sep 1
PMID: 24003212
A ZO-1/a5ß1-integrin complex regulates cytokinesis downstream of PKCe in NCI-H460 cells plated on fibronectin.
PLoS One 2013;8(8):e70696. Epub 2013 aug 13
PMID: 23967087
Phosphoinositide 3-kinases as accelerators and brakes of autophagy.
FEBS J 2013 Dec;280(24):6322-37. Epub 2013 sep 5
PMID: 23953235
Phosphatidylinositol 3-phosphate, a lipid that regulates membrane dynamics, protein sorting and cell signalling.
Bioessays 2013 Oct;35(10):900-12. Epub 2013 jul 24
PMID: 23881848
Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation.
J Cell Biol 2013 Jul 22;202(2):331-49.
PMID: 23878278
Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties.
J Control Release 2013 Jun 28;168(3):317-26. Epub 2013 apr 6
PMID: 23567040
Spatiotemporal control of Cindr at ring canals during incomplete cytokinesis in the Drosophila male germline.
Dev Biol 2013 May 1;377(1):9-20. Epub 2013 mar 7
PMID: 23499247
Class III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane traffic.
FEBS J 2013 Jun;280(12):2730-42. Epub 2013 feb 6
PMID: 23289851
Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene ß-catenin.
EMBO Rep 2013 Jan;14(1):10-1. Epub 2012 des 11
PMID: 23229585
Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration.
EMBO Rep 2013 Jan;14(1):57-64. Epub 2012 nov 16
PMID: 23154468
Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1.
Biochem J 2012 Jan;441(1):399-406.
PMID: 21936852
p62 at the interface of autophagy, oxidative stress signaling, and cancer.
Antioxid Redox Signal 2012 Sep;17(5):786-93. Epub 2012 jan 11
PMID: 22074114
The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain.
J Cell Sci 2012 Jan;125(Pt 1):29-36. Epub 2012 jan 20
PMID: 22266905
Ubiquitination and phosphorylation of Beclin 1 and its binding partners: Tuning class III phosphatidylinositol 3-kinase activity and tumor suppression.
FEBS Lett 2012 Jun;586(11):1584-91. Epub 2012 mai 3
PMID: 22673570
The PtdIns3P-binding protein Phafin 2 mediates epidermal growth factor receptor degradation by promoting endosome fusion.
Traffic 2012 Nov;13(11):1547-63. Epub 2012 aug 8
PMID: 22816767
The Rabs: a family at the root of metazoan evolution.
BMC Biol 2012;10():68. Epub 2012 aug 8
PMID: 22873178
SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking.
Oncogene 2013 Oct 31;32(44):5220-32. Epub 2012 des 10
PMID: 23222715
Molecular mechanisms of ubiquitin-dependent membrane traffic.
Annu Rev Biophys 2011 Jun;40():119-42.
PMID: 21332354
A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis.
PLoS One 2011;6(3):e17086. Epub 2011 mar 24
PMID: 21455500
Endocytosis and signaling.
Curr Opin Cell Biol 2011 Aug;23(4):393-403. Epub 2011 apr 5
PMID: 21474295
SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis.
Oncogene 2011 Sep;30(37):3967-78. Epub 2011 apr 18
PMID: 21499309
ESCRT proteins and cell signalling.
Traffic 2011 Oct;12(10):1291-7. Epub 2011 mai 13
PMID: 21518165
Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting.
Traffic 2011 Sep;12(9):1211-26. Epub 2011 jun 13
PMID: 21564451
Cell polarity and migration: emerging role for the endosomal sorting machinery.
Physiology (Bethesda) 2011 Jun;26(3):171-80.
PMID: 21670163
Cell differentiation: midbody remnants - junk or fate factors?
Curr Biol 2011 Dec;21(23):R958-60. Epub 2011 des 5
PMID: 22153165
Shaping development with ESCRTs.
Nat Cell Biol 2011;14(1):38-45. Epub 2011 des 22
PMID: 22193162
Novel regulators of the cell cycle
- Disputert:
- mars 2014
- Hovedveileder:
- Harald Alfred Stenmark
Regulation of the endocytic pathway and receptor sorting by phosphoinositides and ESCRTs
- Disputert:
- oktober 2013
- Hovedveileder:
- Harald Alfred Stenmark
Identification of novel regulators of epithelial polarity and cell migration
- Disputert:
- oktober 2012
- Hovedveileder:
- Harald Stenmark
Regulation of cytokinesis and its consequences for human health
- Disputert:
- mars 2012
- Hovedveileder:
- Harald Stenmark
PhD
- Disputert:
- juni 2011
- Hovedveileder:
- Harald Stenmark
- Marina Vietri Prosjektdeltaker
- Coen Campsteijn Prosjektdeltaker
- Kaisa Haglund Prosjektdeltaker
- Ellen Skarpen Prosjektdeltaker
- Kay Oliver Schink Prosjektdeltaker
- Andreas John Carl Brech Prosjektdeltaker
- Camilla Raiborg Prosjektdeltaker
- Harald Alfred Stenmark Prosjektleder
- Nina Marie Pedersen Biveileder
- Sigrid Bratlie Thoresen Doktorgradsstipendiat
- Marianne Smestad Prosjektdeltaker
- Eva Wenzel Postdoktorstipendiat
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