Regulation of membrane dynamics
- Prosjektnummer
- 2012014
- Ansvarlig person
- Kirsten Sandvig
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Doktorgradsstipend
- Helsekategori
- Cancer
- Forskningsaktivitet
- 5. Treatment Developement
Different roles of the C-terminal end of Stx1A and Stx2A for AB5 complex integrity and retrograde transport of Stx in HeLa cells.
Pathog Dis 2015 Dec;73(9):ftv083. Epub 2015 okt 5
PMID: 26443836
Cross-linking of glycosphingolipids at the plasma membrane: consequences for intracellular signaling and traffic.
Cell Mol Life Sci 2016 Mar;73(6):1301-16. Epub 2015 sep 25
PMID: 26407609
Novel actions of 2-deoxy-D-glucose: protection against Shiga toxins and changes in cellular lipids.
Biochem J 2015 Aug 15;470(1):23-37. Epub 2015 jun 11
PMID: 26251444
Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells.
PLoS One 2015;10(5):e0129214. Epub 2015 mai 27
PMID: 26017782
Vps11, a subunit of the tethering complexes HOPS and CORVET, is involved in regulation of glycolipid degradation and retrograde toxin transport.
Commun Integr Biol 2014 Jan 1;7(1):e28129. Epub 2014 apr 3
PMID: 24778763 - Inngår i doktorgradsavhandlingen
Lipid requirements for entry of protein toxins into cells.
Prog Lipid Res 2014 Apr;54():1-13. Epub 2014 jan 23
PMID: 24462587
The ERM proteins ezrin and moesin regulate retrograde Shiga toxin transport.
Traffic 2013 Jul;14(7):839-52. Epub 2013 mai 28
PMID: 23593995 - Inngår i doktorgradsavhandlingen
Retrograde transport of protein toxins through the Golgi apparatus.
Histochem Cell Biol 2013 Sep;140(3):317-26. Epub 2013 jun 14
PMID: 23765164
Genetic blockage of endocytic pathways reveals differences in the intracellular processing of non-viral gene delivery systems.
J Control Release 2012 Nov;163(3):385-95. Epub 2012 okt 4
PMID: 23041276
Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells.
Biochim Biophys Acta 2012 Nov-Dec;1819(11-12):1154-63. Epub 2012 sep 8
PMID: 22982408
Shiga toxins.
Toxicon 2012 Nov;60(6):1085-107. Epub 2012 aug 16
PMID: 22960449
Uptake of ricinB-quantum dot nanoparticles by a macropinocytosis-like mechanism.
J Nanobiotechnology 2012;10():33. Epub 2012 jul 31
PMID: 22849338
Annexin A1 and A2: roles in retrograde trafficking of Shiga toxin.
PLoS One 2012;7(7):e40429. Epub 2012 jul 6
PMID: 22792315
Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases.
J Biol Chem 2012 Jun;287(26):21992-2003. Epub 2012 apr 26
PMID: 22539349
Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3.
Mol Cell Proteomics 2012 Jul;11(7):M111.012914. Epub 2012 mar 28
PMID: 22457534
Inhibitors of intravesicular acidification protect against Shiga toxin in a pH-independent manner.
Traffic 2012 Mar;13(3):443-54. Epub 2011 des 21
PMID: 22132807
Shiga toxin: Uptake and transport in cancer cells
- Disputert:
- oktober 2015
- Hovedveileder:
- Kirsten Sandvig
- Alicia Llorente Prosjektleder
- Sascha Pust Forsker (annen finansiering)
- Audun Sverre Myrset Kvalvaag Doktorgradsstipendiat
- Kirsten Sandvig Forskningsgruppeleder
- Roger Simm Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til eRapport