Research Group for Cell Transplantation
- Prosjektnummer
- 2012031
- Ansvarlig person
- Hanne Scholz (Aksel Foss)
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Helse Sør-Øst Forskningsgruppe
- Helsekategori
- Metabolic and Endocrine
- Forskningsaktivitet
- 5. Treatment Developement
Culture at low glucose up-regulates mitochondrial function in pancreatic ß cells with accompanying effects on viability.
Islets 2016 Nov;8(6):165-176. Epub 2016 okt 20
PMID: 27763807
LIGHT/TNFSF14 is increased in patients with type 2 diabetes mellitus and promotes islet cell dysfunction and endothelial cell inflammation in vitro.
Diabetologia 2016 Oct;59(10):2134-44. Epub 2016 jul 15
PMID: 27421726
Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids.
J Diabetes Res 2016;2016():4196460. Epub 2016 jan 18
PMID: 26885529
Evaluation of Perfluorohexyloctane/Polydimethylsiloxane for Pancreas Preservation for Clinical Islet Isolation and Transplantation.
Cell Transplant 2016 Dec 13;25(12):2269-2276. Epub 2016 mai 27
PMID: 27301705
Mitochondrial Respiration in Insulin-Producing ß-Cells: General Characteristics and Adaptive Effects of Hypoxia.
PLoS One 2015;10(9):e0138558. Epub 2015 sep 24
PMID: 26401848
Intracellular sirolimus concentration is reduced by tacrolimus in human pancreatic islets in vitro.
Transpl Int 2015 Oct;28(10):1152-61. Epub 2015 jun 23
PMID: 26046470
Graft function 1 year after pregnancy in an islet-transplanted patient.
Transpl Int 2015 Oct;28(10):1235-9. Epub 2015 mai 11
PMID: 25903157
The effects of exendin-4 treatment on graft failure: an animal study using a novel re-vascularized minimal human islet transplant model.
PLoS One 2015;10(3):e0121204. Epub 2015 mar 20
PMID: 25793295
RAF-targeted therapy for hepatocellular carcinoma in the regenerating liver.
J Surg Oncol 2013 Mar;107(4):393-401. Epub 2012 aug 23
PMID: 22927239
Thioredoxin interacting protein is a potential regulator of glucose and energy homeostasis in endogenous Cushing's syndrome.
PLoS One 2013;8(5):e64247. Epub 2013 mai 17
PMID: 23691179
Anakinra and tocilizumab enhance survival and function of human islets during culture: implications for clinical islet transplantation.
Cell Transplant 2014;23(10):1199-211. Epub 2013 apr 29
PMID: 23635711
Plasma lipoproteins and preeclampsia in women with type 1 diabetes: a prospective study.
J Clin Endocrinol Metab 2012 May;97(5):1752-62. Epub 2012 mar 21
PMID: 22438226
Using HTK for prolonged pancreas preservation prior to human islet isolation.
J Surg Res 2012 Jun;175(1):163-8. Epub 2011 mar 31
PMID: 21550052
Transplanted functional islet mass: donor, islet preparation, and recipient factors influence early graft function in islet-after-kidney patients.
Transplantation 2012 Mar;93(6):632-8.
PMID: 22258287
Reduced soluble receptor for advanced glycation end-products (sRAGE) scavenger capacity precedes pre-eclampsia in Type 1 diabetes.
BJOG 2012 Nov;119(12):1512-20. Epub 2012 aug 20
PMID: 22900949
Anakinra and tocilizumab enhance survival and function of human islets during culture: implications for clinical islet transpl.
Submitted to Am J Transpl. dec 2012
Exendin-4 decreases blood glucose levels, but does not affect other metabolic parameter in transplanted human islets.
The XXIV International Congress of the Transplantation Society Berlin 2012
High donor age have impact on human islets graft mass and the duration of metabolic normalization.
Manuscript in preparation
Targeting islet inflammation; the key to preventing ß-cell loss in islet transplantation
- Disputert:
- oktober 2016
- Hovedveileder:
- Hanne Bjørnson Scholz
- Gunnar Kvalheim Medveileder
- Simen Walberg Schive Doktorgradsstipendiat (finansiert av denne bevilgning)
- Shadab Abadpour Doktorgradsstipendiat (annen finansiering)
- Aksel Foss Medveileder
- Hanne Bjørnson Scholz Prosjektleder
- Afaf Sahraoui Doktorgradsstipendiat (finansiert av denne bevilgning)
- Kristine Kloster-Jensen Doktorgradsstipendiat (finansiert av denne bevilgning)
- Simen Schive Doktorgradsstipendiat
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til eRapport