Therapeutic inhibition of the complement system: identification of target molecules.
- Prosjektnummer
- 2012060
- Ansvarlig person
- Tom Eirik Mollnes
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Postdoktorstipend
- Helsekategori
- Inflammatory and Immune System
- Forskningsaktivitet
- 2. Aetiology
Prediction of inflammatory responses induced by biomaterials in contact with human blood using protein fingerprint from plasma.
Biomaterials 2015 Jan;36():55-65. Epub 2014 okt 5
PMID: 25292422
Complement Activation Correlates With Disease Severity and Contributes to Cytokine Responses in Plasmodium falciparum Malaria.
J Infect Dis 2015 Dec 1;212(11):1835-40. Epub 2015 mai 15
PMID: 25980034
Inflammatory Response After Laparoscopic Versus Open Resection of Colorectal Liver Metastases: Data From the Oslo-CoMet Trial.
Medicine (Baltimore) 2015 Oct;94(42):e1786.
PMID: 26496309
Post challenge inhibition of C3 and CD14 attenuates Escherichia coli-induced inflammation in human whole blood.
Innate Immun 2014 Jan;20(1):68-77. Epub 2013 mai 13
PMID: 23669326
Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by Staphylococcus aureus in a human whole blood model.
J Immunol 2014 Mar 15;192(6):2857-64. Epub 2014 feb 10
PMID: 24516199
Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release.
J Immunol 2014 Mar 15;192(6):2837-45. Epub 2014 feb 19
PMID: 24554772
Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice.
J Immunol 2014 Jun 1;192(11):5324-31. Epub 2014 apr 30
PMID: 24790148
Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn.
Immunobiology 2015 Apr;220(4):452-9. Epub 2014 nov 13
PMID: 25468724
Complement C3 and C5 deficiency affects fracture healing.
PLoS One 2013;8(11):e81341. Epub 2013 nov 18
PMID: 24260573
Letter to editor.
J Clin Biochem Nutr 2013 May;52(3):253-4.
PMID: 23704816
- Tom Eirik Mollnes Prosjektleder
- Per Nilsson Postdoktorstipendiat
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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