Genetic variants and early trauma as predictors of clinical course in psychotic disorders
- Prosjektnummer
- 2013088
- Ansvarlig person
- Ingrid Melle
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Postdoktorstipend
- Helsekategori
- Mental Health
- Forskningsaktivitet
- 1. Underpinning, 2. Aetiology
Affective lability mediates the association between childhood trauma and suicide attempts, mixed episodes and co-morbid anxiety disorders in bipolar disorders.
Psychol Med 2017 Apr;47(5):902-912. Epub 2016 nov 29
PMID: 27894372
A history of childhood trauma is associated with slower improvement rates: Findings from a one-year follow-up study of patients with a first-episode psychosis.
BMC Psychiatry 2016 May 04;16():126. Epub 2016 mai 4
PMID: 27146044
The role of childhood trauma in bipolar disorders.
Int J Bipolar Disord 2016 Dec;4(1):2. Epub 2016 jan 13
PMID: 26763504
Serum concentrations of mood stabilizers are associated with memory, but not other cognitive domains in psychosis spectrum disorders; explorative analyses in a naturalistic setting.
Int J Bipolar Disord 2016 Dec;4(1):24. Epub 2016 des 9
PMID: 27858347
Serum levels of second-generation antipsychotics are associated with cognitive function in psychotic disorders.
World J Biol Psychiatry 2017 Sep;18(6):471-482. Epub 2016 nov 15
PMID: 27712130
Anomalous self-experience and childhood trauma in first-episode schizophrenia.
Compr Psychiatry 2015 Jan;56():35-41. Epub 2014 okt 16
PMID: 25458477
Polygenic risk scores in bipolar disorder subgroups.
J Affect Disord 2015 Sep 1;183():310-4. Epub 2015 mai 22
PMID: 26047958
Psychometric properties of the Affective Lability Scale (54 and 18-item version) in patients with bipolar disorder, first-degree relatives, and healthy controls.
J Affect Disord 2014 Oct 23;172C():375-380. Epub 2014 okt 23
PMID: 25451440
Interplay between childhood trauma and BDNF val66met variants on blood BDNF mRNA levels and on hippocampus subfields volumes in schizophrenia spectrum and bipolar disorders.
J Psychiatr Res 2014 Dec;59():14-21. Epub 2014 aug 30
PMID: 25246365
Affective lability in patients with bipolar disorders is associated with high levels of childhood trauma.
Psychiatry Res 2014 Aug 15;218(1-2):252-5. Epub 2014 apr 12
PMID: 24803185
A systematic review of cognitive function in first-episode psychosis, including a discussion on childhood trauma, stress, and inflammation.
Front Psychiatry 2014;4():182. Epub 2014 jan 8
PMID: 24409157
Altered systemic cortisol metabolism in bipolar disorder and schizophrenia spectrum disorders.
J Psychiatr Res 2014 May;52():57-62. Epub 2014 feb 4
PMID: 24534618
High prevalence of childhood trauma in patients with schizophrenia spectrum and affective disorder.
Compr Psychiatry 2013 Feb;54(2):123-7. Epub 2012 aug 15
PMID: 22901835
Patterns of childhood adverse events are associated with clinical characteristics of bipolar disorder.
BMC Psychiatry 2013;13():97. Epub 2013 mar 22
PMID: 23522391
BDNF val66met modulates the association between childhood trauma, cognitive and brain abnormalities in psychoses.
Prog Neuropsychopharmacol Biol Psychiatry 2013 Oct 1;46():181-8. Epub 2013 jul 19
PMID: 23876786
Additive effects of childhood abuse and cannabis abuse on clinical expressions of bipolar disorders.
Psychol Med 2014 Jun;44(8):1653-62. Epub 2013 sep 13
PMID: 24028906
Childhood trauma is associated with severe clinical characteristics of bipolar disorders.
J Clin Psychiatry 2013 Oct;74(10):991-8.
PMID: 24229750
- Ingrid Melle Prosjektleder
- Monica Aas Postdoktorstipendiat (finansiert av denne bevilgning)
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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