Early clinical and molecular characterization of Inflammatory Bowel Disease in adults and pediatric patients. Relationship between gut barrier dysfunction and dysbiosis in treatment naïve, newly diagnosed patients.
- Prosjektnummer
- 2014011
- Ansvarlig person
- Jørgen Jahnsen
- Institusjon
- Akershus universitetssykehus HF
- Prosjektkategori
- Postdoktorstipend
- Helsekategori
- Inflammatory and Immune System
- Forskningsaktivitet
- 4. Detection and Diagnosis
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Mucosal Gene Transcript Signatures in Treatment Naïve Inflammatory Bowel Disease: A Comparative Analysis of Disease to Symptomatic and Healthy Controls in the European IBD-Character Cohort.
Clin Exp Gastroenterol 2022;15():5. Epub 2022 feb 11
PMID: 35185343
Systemic Inflammation in Preclinical Ulcerative Colitis.
Gastroenterology 2021 11;161(5):1526-1539.e9. Epub 2021 jul 21
PMID: 34298022
Serum proteomic profiling at diagnosis predicts clinical course, and need for intensification of treatment in inflammatory bowel disease.
J Crohns Colitis 2021 May 04;15(5):699-708.
PMID: 33201212
Age, Inflammation, and Disease Location Are Critical Determinants of Intestinal Expression of SARS-CoV-2 Receptor
Gastroenterology 2020 Sep;159(3):1151-1154.e2. Epub 2020 mai 12
PMID: 32413354
Whole blood profiling of T-cell derived miRNA allows the development of prognostic models in inflammatory bowel disease.
J Crohns Colitis 2020 Jun 29. Epub 2020 jun 29
PMID: 32598439
Faecal microbiota signatures of IBD and their relation to diagnosis, disease phenotype, inflammation, treatment escalation and anti-TNF response in a European Multicentre Study (IBD-Character).
Scand J Gastroenterol 2020 Oct;55(10):1146-1156. Epub 2020 aug 11
PMID: 32780604
The prevalence and transcriptional activity of the mucosal microbiota of ulcerative colitis patients.
Sci Rep 2018 Nov 22;8(1):17278. Epub 2018 nov 22
PMID: 30467421
Simultaneous purification of DNA and RNA from microbiota in a single colonic mucosal biopsy.
BMC Res Notes 2016 Jun 28;9():328. Epub 2016 jun 28
PMID: 27352784
Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease.
Nat Commun 2016 Nov 25;7():13507. Epub 2016 nov 25
PMID: 27886173
- Trond Espen Detlie Doktorgradsstipendiat (annen finansiering)
- Stephan Brackmann Prosjektdeltaker
- Christine Olbjørn Postdoktorstipendiat (annen finansiering)
- Simen Vatn Doktorgradsstipendiat (annen finansiering)
- Morten Vatn Prosjektdeltaker
- Anna Brzozowska Frengen Prosjektdeltaker
- Tone Møller Tannæs Prosjektdeltaker
- Aina Elisabeth Fossum Moen Prosjektdeltaker
- Petr Ricanek Postdoktorstipendiat (finansiert av denne bevilgning)
- Jørgen Jahnsen Prosjektleder
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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