Photochemical internalization to induce rapid tumor vascular shutdown
- Prosjektnummer
- 2014030
- Ansvarlig person
- Kristian Berg
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Doktorgradsstipend
- Helsekategori
- Cancer
- Forskningsaktivitet
- 5. Treatment Developement
5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin.
J Exp Clin Cancer Res 2017 Dec 19;36(1):187. Epub 2017 des 19
PMID: 29258566 - Inngår i doktorgradsavhandlingen
Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance.
Biochem Pharmacol 2017 11 15;144():63-77. Epub 2017 aug 5
PMID: 28784290 - Inngår i doktorgradsavhandlingen
Impact of genotypic and phenotypic differences in sarcoma models on the outcome of photochemical internalization (PCI) of bleomycin.
Photodiagnosis Photodyn Ther 2017 Dec;20():35-47. Epub 2017 aug 23
PMID: 28838761 - Inngår i doktorgradsavhandlingen
Deciphering the Nongenomic, Mitochondrial Toxicity of Tamoxifens As Determined by Cell Metabolism and Redox Activity.
ACS Chem Biol 2016 Jan 15;11(1):251-62. Epub 2015 nov 30
PMID: 26569462
Photochemical activation of drugs for the treatment of therapy-resistant cancers.
Photochem Photobiol Sci 2015 Aug;14(8):1465-75. Epub 2015 apr 7
PMID: 25849953
Photochemical internalisation, a minimally invasive strategy for light-controlled endosomal escape of cancer stem cell-targeting therapeutics.
Photochem Photobiol Sci 2015 Aug;14(8):1433-50. Epub 2015 mar 25
PMID: 25805311
Light-controlled endosomal escape of the novel CD133-targeting immunotoxin AC133-saporin by photochemical internalization - A minimally invasive cancer stem cell-targeting strategy.
J Control Release 2015 May 28;206():37-48. Epub 2015 mar 7
PMID: 25758331 - Inngår i doktorgradsavhandlingen
Light-triggered, efficient cytosolic release of IM7-saporin targeting the putative cancer stem cell marker CD44 by photochemical internalization.
Mol Pharm 2014 Aug 4;11(8):2764-76. Epub 2014 jul 2
PMID: 24960585
Light-controlled endosomal escape of the novel CD133-targeting immunotoxin AC133-saporin by photochemical internalization
Submitted for publication, 2015
Mechanisms of Resistance to TPCS2a-Photodynamic Therapy: Implication for Photochemical Internalization
- Disputert:
- november 2017
- Hovedveileder:
- Pål Kristian Selbo
- Anette Weyergang Prosjektdeltaker
- Pål Kristian Selbo Hovedveileder
- Cathrine Elisabeth Olsen Doktorgradsstipendiat (finansiert av denne bevilgning)
- Alf Kristian Berg Hovedveileder
- Cathrine Olsen Doktorgradsstipendiat
- Pål Selbo Biveileder
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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