Structural and dynamic investigation of protein-DNA complexes involved in DNA oxidative repair and recombination
- Prosjektnummer
- 2014034
- Ansvarlig person
- Bjørn Dalhus
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Forskerstipend
- Helsekategori
- Cancer, Inflammatory and Immune System
- Forskningsaktivitet
- 1. Underpinning
Nei
NEI
NEI
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Non-flipping DNA glycosylase AlkD scans DNA without formation of a stable interrogation complex.
Commun Biol 2021 07 15;4(1):876. Epub 2021 jul 15
PMID: 34267321
Additive manufacturing of laminar flow cells for single-molecule experiments.
Sci Rep 2019 Nov 14;9(1):16784. Epub 2019 nov 14
PMID: 31727950
Breaking the speed limit with multimode fast scanning of DNA by Endonuclease V.
Nat Commun 2018 12 19;9(1):5381. Epub 2018 des 19
PMID: 30568191
Crystal structure and MD simulation of mouse EndoV reveal wedge motif plasticity in this inosine-specific endonuclease.
Sci Rep 2016 Apr 25;6():24979. Epub 2016 apr 25
PMID: 27108838
Regulation of Human Endonuclease V Activity and Relocalization to Cytoplasmic Stress Granules.
J Biol Chem 2016 Oct 07;291(41):21786-21801. Epub 2016 aug 29
PMID: 27573237
Structural basis for incision at deaminated adenines in DNA and RNA by endonuclease V.
Prog Biophys Mol Biol 2015 Mar;117(2-3):134-42. Epub 2015 mar 28
PMID: 25824682
Synthetic Routes to N-9 Alkylated 8-Oxoguanines; Weak Inhibitors of the Human DNA Glycosylase OGG1.
Molecules 2015;20(9):15944-65. Epub 2015 sep 2
PMID: 26364627
Inosine in DNA and RNA.
Curr Opin Genet Dev 2014 Jun;26():116-23. Epub 2014 aug 30
PMID: 25173738
Single-molecule investigation of DNA scanning by DNA base repair proteins
- Disputert:
- april 2019
- Hovedveileder:
- Bjørn Dalhus
Discovery and characterization of small-molecule inhibitors of 8-oxoguanine DNA glycosylase 1
- Disputert:
- mai 2018
- Hovedveileder:
- Bjørn Dalhus
Design, synthesis and biological evaluation of 8-oxoguanine derivatives as DNA glycosylases inhibitors and ...
- Disputert:
- september 2016
- Hovedveileder:
- Lise-Lotte Gundersen
Molecular and Cellular Insights into Mammalian Endonuclease V
- Disputert:
- november 2016
- Hovedveileder:
- Ingrun Alseth
- Miroslava Kissova Prosjektdeltaker
- Mark Schüttpelz Prosjektdeltaker
- Kyrre Harald Glette Prosjektdeltaker
- Jim Tørresen Prosjektdeltaker
- Alexander D. Rowe Prosjektdeltaker
- Ingrun Alseth Prosjektdeltaker
- Magnar Bjørås Prosjektdeltaker
- Ane-Sofie Bednarcz Hansen Prosjektdeltaker
- Pernille Blicher Prosjektdeltaker
- Øyvind Jacobsen Postdoktorstipendiat (annen finansiering)
- Arash Ahmadi Doktorgradsstipendiat (annen finansiering)
- Mari Ytre-Arne Doktorgradsstipendiat (annen finansiering)
- Bjørn Dalhus Prosjektleder
- Meh Sameen Nawaz Prosjektdeltaker
- Tushar Ravindra Mahajan Prosjektdeltaker
- Lise-Lotte Gundersen Prosjektdeltaker
- Hanne Korvald Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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