Exploring the contribution of bromodomain-containing proteins to prostate cancer and prostate cancer risk.
- Prosjektnummer
- 2014040
- Ansvarlig person
- Ian Mills
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Postdoktorstipend
- Helsekategori
- Cancer
- Forskningsaktivitet
- 1. Underpinning
NO
Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer.
BMC Genomics 2017 03 31;18(1):270. Epub 2017 mar 31
PMID: 28359301
Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer.
Cell Rep 2017 Jun 06;19(10):2045-2059.
PMID: 28591577
Bromodomain-containing proteins in prostate cancer.
Mol Cell Endocrinol 2017 Jun 15. Epub 2017 jun 15
PMID: 28624514
Cell cycle-coupled expansion of AR activity promotes cancer progression.
Oncogene 2016 Sep 26. Epub 2016 sep 26
PMID: 27669432
CTCF modulates Estrogen Receptor function through specific chromatin and nuclear matrix interactions.
Nucleic Acids Res 2016 Dec 15;44(22):10588-10602. Epub 2016 sep 15
PMID: 27638884
Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells.
Epigenetics Chromatin 2016;9():21. Epub 2016 mai 31
PMID: 27252783
HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer.
Oncotarget 2016 Nov 15;7(46):74734-74746.
PMID: 27732966
Mapping Protein-DNA Interactions Using ChIP-exo and Illumina-Based Sequencing.
Methods Mol Biol 2016;1443():119-37.
PMID: 27246337
Gene regulatory mechanisms underpinning prostate cancer susceptibility.
Nat Genet 2016 Apr;48(4):387-97. Epub 2016 mar 7
PMID: 26950096
Myc-dependent purine biosynthesis affects nucleolar stress and therapy response in prostate cancer.
Oncotarget 2015 May 20;6(14):12587-602.
PMID: 25869206
CIP2A is a candidate therapeutic target in clinically challenging prostate cancer cell populations.
Oncotarget 2015 Aug 14;6(23):19661-70.
PMID: 25965834
Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment.
PLoS One 2015;10(4):e0123684. Epub 2015 apr 10
PMID: 25860483
Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci.
PLoS One 2015;10(12):e0144531. Epub 2015 des 22
PMID: 26695485
The Early Effects of Rapid Androgen Deprivation on Human Prostate Cancer.
Eur Urol 2015 Nov 10. Epub 2015 nov 10
PMID: 26572708
A differential protein solubility approach for the depletion of highly abundant proteins in plasma using ammonium sulfate.
Analyst 2015 Nov 23;140(24):8109-17.
PMID: 26541119
Maintaining a Healthy Balance: Targeting TERT to Stem Benign Prostatic Hyperplasia.
Eur Urol 2015 Oct 28. Epub 2015 okt 28
PMID: 26520704
Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study.
EBioMedicine 2015 Sep;2(9):1133-44. Epub 2015 jul 29
PMID: 26501111
The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer.
Oncotarget 2015 Oct 27;6(33):34358-74.
PMID: 26452038
Glucocorticoid receptor and Klf4 co-regulate anti-inflammatory genes in keratinocytes.
Mol Cell Endocrinol 2015 Sep 5;412():281-9. Epub 2015 mai 19
PMID: 26001834
Molecular subtyping of prostate cancer: a partnership model.
Eur Urol 2015 Oct;68(4):568-9. Epub 2015 mai 20
PMID: 26001612
Divergent androgen regulation of unfolded protein response pathways drives prostate cancer.
EMBO Mol Med 2015 Jun;7(6):788-801. Epub 2015 apr 11
PMID: 25864123
UAP1 is overexpressed in prostate cancer and is protective against inhibitors of N-linked glycosylation.
Oncogene 2015 Jul;34(28):3744-50. Epub 2014 sep 22
PMID: 25241896
Meta-analysis of prostate cancer gene expression data identifies a novel discriminatory signature enriched for glycosylating enzymes.
BMC Med Genomics 2014 Dec 31;7(1):513. Epub 2014 des 31
PMID: 25551447
Androgen-regulated metabolism and biosynthesis in prostate cancer.
Endocr Relat Cancer 2014 Aug;21(4):T57-66. Epub 2014 feb 4
PMID: 24497572
Salt-inducible Kinase 2 Regulates Mitotic Progression and Transcription in Prostate Cancer.
Mol Cancer Res 2014 Dec 29. Epub 2014 des 29
PMID: 25548099
Endosomal signaling and oncogenesis.
Methods Enzymol 2014;535():179-200.
PMID: 24377925
Maintaining and reprogramming genomic androgen receptor activity in prostate cancer.
Nat Rev Cancer 2014 Mar;14(3):187-98.
PMID: 24561445
The molecular signature of the stroma response in prostate cancer-induced osteoblastic bone metastasis highlights expansion of hematopoietic and prostate epithelial stem cell niches.
PLoS One 2014;9(12):e114530. Epub 2014 des 8
PMID: 25485970
HES6 drives a critical AR transcriptional programme to induce castration-resistant prostate cancer through activation of an E2F1-mediated cell cycle network.
EMBO Mol Med 2014 May;6(5):651-61. Epub 2014 mai 1
PMID: 24737870
The ETS family member GABPa modulates androgen receptor signalling and mediates an aggressive phenotype in prostate cancer.
Nucleic Acids Res 2014 Jun;42(10):6256-69. Epub 2014 apr 21
PMID: 24753418
Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer.
EMBO J 2014 Jun 17;33(12):1365-82. Epub 2014 mai 16
PMID: 24837709
Shared common variants in prostate cancer and blood lipids.
Int J Epidemiol 2014 Aug;43(4):1205-14. Epub 2014 apr 30
PMID: 24786909
The transcriptional role of c-Myc in prostate cancer
- Disputert:
- oktober 2015
- Hovedveileder:
- Dr Ian Mills
- Alfonso Urbanucci Postdoktorstipendiat (finansiert av denne bevilgning)
- Ian Geoffrey Mills Prosjektleder
- Stefan Barfeld Doktorgradsstipendiat
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til eRapport