Using stem cells to understand the underlying mechanisms of polygenic risk of severe mental disorders
- Prosjektnummer
- 2014101
- Ansvarlig person
- Srdjan Djurovic
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Åpen prosjektstøtte
- Helsekategori
- Mental Health
- Forskningsaktivitet
- 1. Underpinning
Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia.
Mol Psychiatry 2017 Jun;22(6):792-801. Epub 2017 mar 28
PMID: 28348379
Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function.
JAMA Psychiatry 2017 Oct 01;74(10):1065-1075.
PMID: 28746715
Genetic Overlap Between Schizophrenia and Volumes of Hippocampus, Putamen, and Intracranial Volume Indicates Shared Molecular Genetic Mechanisms.
Schizophr Bull 2018 06 06;44(4):854-864.
PMID: 29136250
Modeling psychiatric disorders: from genomic findings to cellular phenotypes.
Mol Psychiatry 2016 Sep;21(9):1167-79. Epub 2016 mai 31
PMID: 27240529
The roadmap for estimation of cell-type-specific neuronal activity from non-invasive measurements.
Philos Trans R Soc Lond B Biol Sci. 2016 Oct 5;371(1705).
Functional Effects of Schizophrenia-Linked Genetic Variants on Intrinsic Single-Neuron Excitability: A Modeling Study.
Biol Psychiatry Cogn Neurosci Neuroimaging. 2016 Jan 1;1(1):49-59.
Modeling psychiatric disorders: from genomic findings to cellular phenotypes.
Mol Psychiatry. 2016 Sep;21(9):1321.
Cell type specificity of neurovascular coupling in cerebral cortex.
Elife. 2016 May 31;5. pii: e14315
The Endogenous Hallucinogen and Trace Amine N,N-Dimethyltryptamine (DMT) Displays Potent Protective Effects against Hypoxia via Sigma-1 Receptor Activation in Human Primary iPSC-Derived Cortical Neurons and Microglia-Like Immune Cells.
Front Neurosci. 2016 Sep 14;10:423.
- Ole Andreas Andreassen Forskningsgruppeleder
- Gareth Sullivan Forsker (annen finansiering)
- Joel Glover Forskningsgruppeleder
- Agata Antonina Rita Impellizzeri Postdoktorstipendiat (finansiert av denne bevilgning)
- Srdjan Djurovic Prosjektleder
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til eRapport