The beta-catenin destruction complex in physiology and disease.
- Prosjektnummer
- 2015014
- Ansvarlig person
- Eva Maria Wenzel
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Forskerstipend
- Helsekategori
- Cancer
- Forskningsaktivitet
- 1. Underpinning
NEI
Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation.
Nat Commun 2018 07 26;9(1):2932. Epub 2018 jul 26
PMID: 30050131
ESCRT-mediated lysosome repair precedes lysophagy and promotes cell survival.
EMBO J 2018 Nov 02;37(21). Epub 2018 okt 12
PMID: 30314966
Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery.
Trends Biochem Sci 2017 Jan;42(1):42-56. Epub 2016 sep 23
PMID: 27669649
Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and β-Catenin Degradation.
PLoS One 2017;12(1):e0170508. Epub 2017 jan 20
PMID: 28107521
Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation.
Nat Cell Biol 2017 Dec;19(12):1412-1423. Epub 2017 okt 30
PMID: 29084199
Targeting Tankyrase to Fight WNT-dependent Tumours.
Basic Clin Pharmacol Toxicol 2017 Aug;121(2):81-88. Epub 2017 mai 10
PMID: 28371398
ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission.
J Cell Biol 2016 Feb 29;212(5):499-513.
PMID: 26929449
Phosphoinositides in membrane contact sites.
Biochem Soc Trans 2016 Apr 15;44(2):425-30.
PMID: 27068950
ER-endosome contact sites in endosome positioning and protrusion outgrowth.
Biochem Soc Trans 2016 Apr 15;44(2):441-6.
PMID: 27068952
Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity.
PLoS One 2016;11(8):e0160507. Epub 2016 aug 2
PMID: 27482906
Surface Trafficking of APP and BACE in Live Cells.
Traffic 2015 Jun;16(6):655-75. Epub 2015 apr 14
PMID: 25712587
Repeated ER-endosome contacts promote endosome translocation and neurite outgrowth.
Nature 2015 Apr 9;520(7546):234-8.
PMID: 25855459
ER-endosome contact sites: molecular compositions and functions.
EMBO J 2015 Jul 14;34(14):1848-58. Epub 2015 jun 3
PMID: 26041457
Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes.
Mol Cancer Res 2015 Nov;13(11):1487-501. Epub 2015 jun 29
PMID: 26124443
- Tor Espen Thorvaldsen Prosjektdeltaker
- Eva Wenzel Prosjektleder
- Nina Marie Pedersen Prosjektdeltaker
- Camilla Raiborg Forskningsgruppeleder
- Harald Alfred Stenmark Forskningsgruppeleder
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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