From genome-wide association studies to antigenic triggers of PSC
- Prosjektnummer
- 2015024
- Ansvarlig person
- Tom Hemming Karlsen
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Postdoktorstipend
- Helsekategori
- Inflammatory and Immune System, Oral and Gastrointestinal
- Forskningsaktivitet
- 1. Underpinning, 2. Aetiology
Nei
Nei
NEI
Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin.
Nat Immunol 2019 12;20(12):1644-1655. Epub 2019 okt 21
PMID: 31636468
Alterations of the bile microbiome in primary sclerosing cholangitis.
Gut 2019 Jun 26. Epub 2019 jun 26
PMID: 31243055
Cholangiocyte pathobiology.
Nat Rev Gastroenterol Hepatol 2019 05;16(5):269-281.
PMID: 30850822
Consistent alterations in faecal microbiomes of patients with primary sclerosing cholangitis independent of associated colitis.
Aliment Pharmacol Ther 2019 Sep;50(5):580-589. Epub 2019 jun 28
PMID: 31250469
Gut and Liver B Cells of Common Clonal Origin in Primary Sclerosing Cholangitis-Inflammatory Bowel Disease.
Hepatol Commun 2018 Aug;2(8):956-967. Epub 2018 aug 6
PMID: 30094406
Overview of methodologies for T-cell receptor repertoire analysis.
BMC Biotechnol 2017 Jul 10;17(1):61. Epub 2017 jul 10
PMID: 28693542
Genetic Discoveries Highlight Environmental Factors as Key Drivers of Liver Disease.
Dig Dis 2017;35(4):323-333. Epub 2017 mai 3
PMID: 28468012
Genetics of primary sclerosing cholangitis and pathophysiological implications.
Nat Rev Gastroenterol Hepatol 2017 May;14(5):279-295. Epub 2017 mar 15
PMID: 28293027
Phenotyping and auto-antibody production by liver-infiltrating B cells in primary sclerosing cholangitis and primary biliary cholangitis.
J Autoimmun 2017 Feb;77():45-54. Epub 2016 okt 24
PMID: 27784538
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.
Nat Genet 2017 Feb;49(2):269-273. Epub 2016 des 19
PMID: 27992413
Antineutrophil antibodies define clinical and genetic subgroups in primary sclerosing cholangitis.
Liver Int 2016 Aug 25. Epub 2016 aug 25
PMID: 27558072
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
Nat Genet 2016 May;48(5):510-8. Epub 2016 mar 14
PMID: 26974007
High-throughput T-cell receptor sequencing across chronic liver diseases reveals distinct disease-associated repertoires.
Hepatology 2016 May;63(5):1608-19. Epub 2015 sep 30
PMID: 26257205
Phenotyping and auto-antibody production by liver-infiltrating B cells in primary sclerosing cholangitis (...)
Journal of Autoimmunity epub 2016 (endelig 2017 PMID 27784538)
Gut and liver T-cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease
Journal of Hepatology epub 2016 (endelig 2017 PMID 27647428)
Anti-GP2 IgA autoantibodies are associated with poor survival and cholangiocarcinoma in primary sclerosing cholangitis
Gut epub 2016 (endelig 2017 PMID 27406039)
- Tuula Anneli Nyman Prosjektdeltaker
- Andre Franke Medveileder
- Espen Melum Medveileder
- Johannes Espolin Roksund Hov Prosjektdeltaker
- Johanna Olweus Medveileder
- Benedicte Alexandra Lie Prosjektdeltaker
- Fridtjof Lund-Johansen Prosjektdeltaker
- Gideon Hirchfield Medveileder
- Evaggelia Liaskou Medveileder
- James Traherne Prosjektdeltaker
- Vasilis Kosmoliaptsis Prosjektdeltaker
- Murat Gainullin Postdoktorstipendiat (finansiert av denne bevilgning)
- Brian Chung Prosjektdeltaker
- Eva Kristine Klemsdal Henriksen Prosjektdeltaker
- Tom Hemming Karlsen Hovedveileder
- Gupta Udatha Postdoktorstipendiat (finansiert av denne bevilgning)
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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