A multicenter study in early rheumatoid arthritis to compare conventional versus biologic treatment and examine de-escalation strategies
- Prosjektnummer
- 2015108
- Ansvarlig person
- Espen A Haavardsholm
- Institusjon
- Diakonhjemmet Sykehus AS
- Prosjektkategori
- Helseforsk - tverregionale forskningsmidler
- Helsekategori
- Inflammatory and Immune System, Musculoskeletal
- Forskningsaktivitet
- 7. Disease Management
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Methotrexate Safety and Efficacy in Combination Therapies in Patients With Early Rheumatoid Arthritis: A Post Hoc Analysis of a Randomized Controlled Trial.
Arthritis Rheumatol 2023 Oct 17. Epub 2023 okt 17
PMID: 37846618
Certolizumab pegol, abatacept, tocilizumab or active conventional treatment in early rheumatoid arthritis: 48-week clinical and radiographic results of the investigator-initiated randomised controlled NORD-STAR trial.
Ann Rheum Dis 2023 Oct;82(10):1286. Epub 2023 jul 9
PMID: 37423647
Blood chemokine levels are markers of disease activity but not predictors of remission in early rheumatoid arthritis.
Clin Exp Rheumatol 2022 Jul;40(7):1393. Epub 2021 nov 3
PMID: 34796837
Plasma interferon-alpha is associated with double-positivity for autoantibodies but is not a predictor of remission in early rheumatoid arthritis-a spin-off study of the NORD-STAR randomized clinical trial.
Arthritis Res Ther 2021 07 13;23(1):189. Epub 2021 jul 13
PMID: 34256800
Active conventional treatment and three different biological treatments in early rheumatoid arthritis: phase IV investigator initiated, randomised, observer blinded clinical trial.
BMJ 2020 12 02;371():m4328. Epub 2020 des 2
PMID: 33268527
Head-to-head comparison of aggressive conventional therapy and three biological treatments and comparison of two de-escalation strategies in patients who respond to treatment: study protocol for a multicenter, randomized, open-label, blinded-assessor, phase 4 study.
Trials 2017 Apr 04;18(1):161. Epub 2017 apr 4
PMID: 28376912
Sex differences in remission rates over 24 weeks among three different biological treatments compared to conventional therapy in patients with early rheumatoid arthritis (NORD-STAR): a post-hoc analysis of a randomised controlled trial
Lancet Rheumatol 2022
- Hilde Berner Hammer Forsker (annen finansiering)
- Amirhossein Kazemi Forskningspersonell
- Joseph Andrew Sexton Forskningspersonell
- David John Stevens Prosjektdeltaker
- Eli Brodin Prosjektdeltaker
- Maud-Kristine Aga Ljoså Prosjektdeltaker
- Gunnstein Bakland Prosjektdeltaker
- Ellen Moholt Prosjektdeltaker
- Camilla Fongen Prosjektdeltaker
- Anna-Birgitte Aga Postdoktorstipendiat (finansiert av denne bevilgning)
- Marte Schrumpf Heiberg Postdoktorstipendiat (annen finansiering)
- Tillmann Uhlig Prosjektdeltaker
- Tore Kristian Kvien Forskningsgruppeleder
- Espen Andre Haavardsholm Prosjektleder
- Erik Rødevand Prosjektdeltaker
- Clara Gram Gjesdal Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til eRapport