Implantable sensors for real-time detection of organ pathology; Multicenter studies
- Prosjektnummer
- 2016115
- Ansvarlig person
- Tor Inge Tønnessen
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Åpen prosjektstøtte
- Helsekategori
- Cardiovascular, Infection, Inflammatory and Immune System, Injuries and Accidents, Oral and Gastrointestinal
- Forskningsaktivitet
- 4. Detection and Diagnosis
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Early detection of anastomotic leakage after pancreatoduodenectomy with microdialysis catheters: an observational Study.
HPB (Oxford) 2022 Jun;24(6):901. Epub 2021 nov 5
PMID: 34836755
Microdialysis and CO2 sensors detect pancreatic ischemia in a porcine model.
PLoS One 2022;17(2):e0262848. Epub 2022 feb 10
PMID: 35143517
Small intestinal viability assessment using dielectric relaxation spectroscopy and deep learning.
Sci Rep 2022 Feb 28;12(1):3279. Epub 2022 feb 28
PMID: 35228559
Utilization of dielectric properties for assessment of liver ischemia-reperfusion injury in vivo and during machine perfusion.
Sci Rep 2022 Jul 01;12(1):11183. Epub 2022 jul 1
PMID: 35778457
Assessment of Intestinal Ischemia-Reperfusion Injury Using Diffuse Reflectance VIS-NIR Spectroscopy and Histology.
Sensors (Basel) 2022 Nov 24;22(23). Epub 2022 nov 24
PMID: 36501812
Intraperitoneal microdialysis detects intestinal leakage earlier than hemodynamic surveillance and systemic inflammation in a pig model.
Scand J Gastroenterol 2021 Feb;56(2):219-227. Epub 2020 des 28
PMID: 33356757
Bile is a promising gut nutrient that inhibits intestinal bacterial translocation and promotes gut motility via an interleukin-6-related pathway in an animal model of endotoxemia.
Nutrition 2021 04;84():111064. Epub 2020 nov 16
PMID: 33418232
Early detection of complications in pancreas transplants by microdialysis catheters, an observational feasibility study.
PLoS One 2021;16(3):e0247615. Epub 2021 mar 11
PMID: 33705460
Ethyl pyruvate supplemented in drinking water ameliorates experimental nonalcoholic steatohepatitis.
Biomed Pharmacother 2021 May;137():111392. Epub 2021 feb 19
PMID: 33761609
Monitoring of patients with microdialysis following pancreaticoduodenectomy-the MINIMUM study: study protocol for a randomized controlled trial.
Trials 2021 May 07;22(1):329. Epub 2021 mai 7
PMID: 33962656
Automatic Prediction of Ischemia-Reperfusion Injury of Small Intestine Using Convolutional Neural Networks: A Pilot Study.
Sensors (Basel) 2021 Oct 08;21(19). Epub 2021 okt 8
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Assessing Ischemic Injury in Human Intestine Ex Vivo with Electrical Impedance Spectroscopy.
J Electr Bioimpedance 2021 Jan;12(1):82-88. Epub 2021 nov 29
PMID: 34966469
An Increased Lactate-to-pyruvate Ratio Is Not a Stand-alone Marker of Ischemia.
Transplant Direct 2020 May;6(5):e551. Epub 2020 apr 22
PMID: 32548245
Endotoxin Removal in Septic Shock with the Alteco LPS Adsorber Was Safe But Showed no Benefit Compared to Placebo in the Double-Blind Randomized Controlled Trial-the Asset Study.
Shock 2020 08;54(2):224-231.
PMID: 31880758
Small intestinal ischemia and reperfusion-bioimpedance measurements.
Physiol Meas 2018 02 26;39(2):025001. Epub 2018 feb 26
PMID: 29303488
Ischemia/reperfusion injury in porcine intestine - Viability assessment.
World J Gastroenterol 2018 May 14;24(18):2009-2023.
PMID: 29760544
Bile and circulating HMGB1 contributes to systemic inflammation in obstructive jaundice.
J Surg Res 2018 Aug;228():14-19. Epub 2018 mar 21
PMID: 29907203
Machine learning for intraoperative prediction of viability in ischemic small intestine.
Physiol Meas 2018 Oct 24;39(10):105011. Epub 2018 okt 24
PMID: 30207981
Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function.
Basic Res Cardiol 2017 May;112(3):20. Epub 2017 mar 3
PMID: 28258298
HMGB1 and Histones Play a Significant Role in Inducing Systemic Inflammation and Multiple Organ Dysfunctions in Severe Acute Pancreatitis.
Int J Inflam 2017;2017():1817564. Epub 2017 feb 21
PMID: 28316860
Ischemic small intestine-in vivo versus ex vivo bioimpedance measurements.
Physiol Meas 2017 May;38(5):715-728. Epub 2017 mar 20
PMID: 28319030
HMGB1 and Extracellular Histones Significantly Contribute to Systemic Inflammation and Multiple Organ Failure in Acute Liver Failure.
Mediators Inflamm 2017;2017():5928078. Epub 2017 jun 13
PMID: 28694564
In vivo characterization of ischemic small intestine using bioimpedance measurements.
Physiol Meas 2016 Feb;37(2):257-75. Epub 2016 jan 25
PMID: 26805916
Abdominal Septic Shock - Endotoxin Adsorption Treatment (ASSET) - endotoxin removal in abdominal and urogenital septic shock with the Alteco® LPS Adsorber: study protocol for a double-blinded, randomized placebo-controlled trial.
Trials 2016 Dec 08;17(1):587. Epub 2016 des 8
PMID: 27931259
Ethyl pyruvate is a novel anti-inflammatory agent to treat multiple inflammatory organ injuries.
J Inflamm (Lond) 2016;13():37. Epub 2016 des 3
PMID: 27980458
Assessment of small intestinal viability - A bioimpedance approach
- Disputert:
- april 2019
- Hovedveileder:
- Jan Olav Høgetveit
- Egil Dahle Brukerrepresentant
- Sven Olav Løstegaard Doktorgradsstipendiat (annen finansiering)
- Jie Hou Doktorgradsstipendiat (annen finansiering)
- Jan Olav Høgetveit Hovedveileder
- Stina Hødnebø Doktorgradsstipendiat (annen finansiering)
- Simen Brændhaugen Brukerrepresentant
- Per Einar Uggen Prosjektdeltaker
- Erik Solligård Prosjektdeltaker
- Kim Aleksander Tønseth Prosjektdeltaker
- Magne Røkkum Prosjektdeltaker
- Runar James Strand-Amundsen Prosjektdeltaker
- Tom Eirik Mollnes Prosjektdeltaker
- Håkon Haugaa Medveileder
- Søren Erik Pischke Prosjektdeltaker
- Anne Waage Prosjektdeltaker
- Knut Jørgen Labori Prosjektdeltaker
- Sheraz Yaqub Prosjektdeltaker
- Espen Eivind Lindholm Postdoktorstipendiat (finansiert av denne bevilgning)
- Nil Ekiz Doktorgradsstipendiat (finansiert av denne bevilgning)
- Bjørn Atle Bjørnbeth Prosjektdeltaker
- Tor Inge Tønnessen Prosjektleder
- Pål Dag Line Prosjektdeltaker
- Gisli Bjørn Bergmann Doktorgradsstipendiat (annen finansiering)
- Runkuan Yang Forsker (annen finansiering)
- Lars Holhjem Postdoktorstipendiat (annen finansiering)
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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