A systems approach to gastrointestinal cancer: Improving insights into disease mechanisms by molecular models from genome-wide screening
- Prosjektnummer
- 46049400
- Ansvarlig person
- Torunn Bruland
- Institusjon
- NTNU, IKM
- Prosjektkategori
- Forskerstipend 2011
- Helsekategori
- Cancer, Oral and Gastrointestinal
- Forskningsaktivitet
- 1. Underpinning, 4. Detection and Diagnosis
Salt-inducible kinase 1 (SIK1) is induced by gastrin and inhibits migration of gastric adenocarcinoma cells.
PLoS One 2014;9(11):e112485. Epub 2014 nov 10
PMID: 25384047
NR4A2 is regulated by gastrin and influences cellular responses of gastric adenocarcinoma cells.
PLoS One 2013;8(9):e76234. Epub 2013 sep 27
PMID: 24086717
The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis.
BMC Genomics 2013;14():429. Epub 2013 jun 28
PMID: 23805861
Gastrin-induced proliferation involves MEK partner 1 (MP1).
In Vitro Cell Dev Biol Anim 2013 Mar;49(3):162-9. Epub 2013 feb 14
PMID: 23408059
Gastrin upregulates the prosurvival factor secretory clusterin in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic rats.
Am J Physiol Gastrointest Liver Physiol 2012 Jan;302(1):G21-33. Epub 2011 okt 13
PMID: 21995960
Conference Paper: Su1918 Molecular Mechanisms of Cellular Stress Responses in Gastric Cancer_
Gastroenterology_Volume 146, Issue 5, Supplement 1, Page S-501, May 2014
NR4A2 is regulated by gastrin and influences cellular responses in gastric adenocarcinoma cells.
Poster ved Nuclear receptors: Linking molecules, genomes & physiology; 2013-09-06 - 2013-09-10 Sorrento, Italy
Gastric cancer biology – clusterin facilitates the growth promoting effects of gastrin.
Poster ved NBS Contact Meeting 2013; 2013-01-31 - 2013-02-03al, årstall
Gene expression analysis of the proliferative zone in gastric oxyntic mucosa
Legestudentenes forskningskonferanse (Frampeik); 2013-10-18 - 2013-10-20tall
Poster Number: 173 . Title: LRH1/NR5A2, a link between pancreatitis and pancreatic cancer?
Location: Royal Dublin Society, Dublin, Ireland.The Role of Inflammation during Carcinogenesis (E2) Dates: May 20 - May 25, 2012
Gastric cancer biology – clusterin facilitates the growth promoting effects of gastrin
Norwegian Biochemical Society Contact meeting 2013; Lillehammer, 31 January-3 February 2013
Gastrin-induced proliferation involves MEK partner 1 (MP1)
In Vitro Cellular & Developmental Biology. In Press 2013
Automated Assessment of High Throughput Hypotheses on Gene Regulatory Mechanisms Involved in the Gastrin Response.
Bio-Ontologies 2011; 2011-07-15 - 2011-07-16
Gastrin upregulates the prosurvival factor secretory clusterin in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic
Am J Physiol Gastrointest Liver Physiol. 2012 Jan;302(1):G21-33. Epub 2011 Oct 13.
Gastrin-mediated regulation of gene expression; a systems biology approach
- Disputert:
- desember 2012
- Hovedveileder:
- Torunn Bruland
- Torunn Bruland Prosjektleder
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Helse Midt-Norge RHF - Samarbeidsorganet og FFU