Chronic obstructive pulmonary disease in Norway: prevalence, classification, hospitalisation, and mortality
We will investigate pre- and post-bronchodilator lung function, spirometric GOLD grades, and ABCD groups and the risk of hospitalisations, cardiovascular and all-cause mortality. Since the diagnostic criteria for COPD was changed in 2011, the scientific community has demanded scientific evidence for the choices. Many research groups including our own have been working intensively to investigate these new criteria. Using data from The Nord-Trøndelag Health Study, Leivseth et al. found post-bronchodilator spirometric GOLD grades to predict mortality substantially better than ABCD groups among women and men. Our group will continue this research and compare diagnosis and classification of COPD, describe symptoms and exacerbations, estimate prevalence in the Norwegian population, compare testing methods for diagnosis and classification of COPD, and investigate the choices of symptom and exacerbation measures and cut-offs of the current COPD classification. This project started in September 2016. Since then applications have been sent and approved for the project from the Regional Ethic Committee. An application for HUNT data has been made and approved. The application for the data from the Cause of Death Register have also been sent. Progress on the first paper, estimating the prevalence of COPD in HUNT has been steady. We aim to submit an abstract of this work to the European Respiratory Congress on the 9th of February and a draft of the manuscript is currently underway. Results can be presented after publication. Additionally, we hope to submit an abstract on the prevalence of asthma-COPD overlap to the same conference above. A manuscript on this topic has also been drafted and is close to submission. Results can be presented after publication.