The role of the urokinase plasminogen activator system in gastric carcinogenesis
- Prosjektnummer
- 46055600-52
- Ansvarlig person
- Kristin Gabestad Nørsett
- Institusjon
- NTNU, IKM
- Prosjektkategori
- korttidsprosjekt 2014
- Helsekategori
- Oral and Gastrointestinal
- Forskningsaktivitet
- 1. Underpinning
Balancing potency, metabolic stability and permeability in pyrrolopyrimidine-based EGFR inhibitors.
Eur J Med Chem 2016 Nov 29;124():583-607. Epub 2016 aug 31
PMID: 27614407
Chiral 6-aryl-furo[2,3-d]pyrimidin-4-amines as EGFR inhibitors.
Eur J Med Chem 2016 Aug 25;119():278-99. Epub 2016 apr 25
PMID: 27235841
Connective tissue growth factor is activated by gastrin and involved in gastrin-induced migration and invasion.
Biochem Biophys Res Commun 2016 Jun 17;475(1):119-24. Epub 2016 mai 11
PMID: 27179776
PAI-1 deficiency increases the trophic effects of hypergastrinemia in the gastric corpus mucosa.
Peptides 2016 May;79():83-94. Epub 2016 mar 30
PMID: 27038741
Identification of new 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines as highly potent EGFR-TK inhibitors with Src-family activity.
Eur J Pharm Sci 2014 Aug 1;59():69-82. Epub 2014 apr 24
PMID: 24769040
Gastrin activates autophagy and increases migration and survival of gastric adenocarcinoma cells.
BMC Cancer 2017; 17:68, http://rdcu.be/oHze
PAI-1 inhibits gastrin induced proliferation of the gastric oxyntic mucosa
51thNBS Contact Meeting, Longearbyen, Feb 2015
Connective tissue growth factor is activated by gastrin and involved in gastrin-induced migration and invasion
Manuscript in preparation
Gastrin activates autophagy and protects cells from cisplatin induced cell death
Submitted
PAI-1 deficiency increases the trophic effects of hypergastrinemia in the gastric corpus mucosa
Submitted
PAI-1 inhibits gastrin induced proliferation of the gastric oxyntic mucosa
51th NBS Contact Meeting, Longearbyen, Feb 2015.
Understanding cellular responses induced by gastrin in gastric adenocarcinoma cells
- Disputert:
- desember 2015
- Hovedveileder:
- Liv Thommesen
- Steffen Bugge Prosjektdeltaker
- Bjørn Munkvold Prosjektdeltaker
- Ingunn Bakke Prosjektdeltaker
- Barbara Niederdorfer Prosjektdeltaker
- Guri Solum Prosjektdeltaker
- J Dinesh Kumar Prosjektdeltaker
- Andrea Varro Prosjektdeltaker
- Sabin Bhandari Prosjektdeltaker
- Svein Jacob Kaspersen Prosjektdeltaker
- Jin Han Prosjektdeltaker
- Eirik Sundby Prosjektdeltaker
- Geir Bjørkøy Prosjektdeltaker
- Bård Helge Hoff Prosjektdeltaker
- Patricia Gjertrud Mjønes Doktorgradsstipendiat
- Reidar Fossmark Prosjektdeltaker
- Vidar Beisvåg Prosjektdeltaker
- Arnar Flatberg Prosjektdeltaker
- Arne Kristian Sandvik Prosjektdeltaker
- Shalini Vasudev Rao Postdoktorstipendiat
- Liv Thommesen Forskningsgruppeleder
- Kristin Gabestad Nørsett Prosjektleder
- Pieter Boekema Prosjektdeltaker
- Patricia Mjønes Postdoktorstipendiat
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Helse Midt-Norge RHF - Samarbeidsorganet og FFU