Translational studies of asbestos-induced human mesothelioma and lung cancer: Meso-Lung HUNT
- Prosjektnummer
- 46056639
- Ansvarlig person
- Oluf Dimitri Røe
- Institusjon
- NTNU, IKM
- Prosjektkategori
- Postdoc-stipend 2012
- Helsekategori
- Cancer
- Forskningsaktivitet
- 4. Detection and Diagnosis
The High Cost of New Cancer Therapies-A Challenge of Inequality for All Countries.
JAMA Oncol 2016 Dec 29. Epub 2016 des 29
PMID: 28033441
Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway.
J Transl Med 2016 Oct 19;14(1):295. Epub 2016 okt 19
PMID: 27756323
JWA loss promotes cell migration and cytoskeletal rearrangement by affecting HER2 expression and identifies a high-risk subgroup of HER2-positive gastric carcinoma patients.
Oncotarget 2016 Jun 14;7(24):36865-36884.
PMID: 27167206
Circulating tumor cells as a prognostic and predictive marker in gastrointestinal stromal tumors: a prospective study.
Oncotarget 2016 Jun 14;7(24):36645-36654.
PMID: 27153560
Prognostic value of perioperative leukocyte count in resectable gastric cancer.
World J Gastroenterol 2016 Mar 07;22(9):2818-27.
PMID: 26973420
Prognostic role of microscopically positive margins for primary gastrointestinal stromal tumors: a systematic review and meta-analysis.
Sci Rep 2016 Feb 19;6():21541. Epub 2016 feb 19
PMID: 26891953
A clinical prognostic scoring system for resectable gastric cancer to predict survival and benefit from paclitaxel- or oxaliplatin-based adjuvant chemotherapy.
Drug Des Devel Ther 2016;10():241-58. Epub 2016 feb 24
PMID: 26966350
Asbestos textile production linked to malignant peritoneal and pleural mesothelioma in women: Analysis of 28 cases in Southeast China.
Am J Ind Med 2015 Oct;58(10):1040-9. Epub 2015 jul 6
PMID: 26147229
The established and future biomarkers of malignant pleural mesothelioma.
Cancer Treat Rev 2015 Jun;41(6):486-95. Epub 2015 mai 8
PMID: 25979846
Activity of pemetrexed-based regimen as first-line chemotherapy for advanced non-small cell lung cancer with asymptomatic inoperable brain metastasis: a retrospective study.
J Chemother 2015 Aug;27(4):221-6. Epub 2015 mar 3
PMID: 25735792
Malignant pleural mesothelioma: history, controversy and future of a manmade epidemic.
Eur Respir Rev 2015 Mar;24(135):115-31.
PMID: 25726562
JWA reverses cisplatin resistance via the CK2-XRCC1 pathway in human gastric cancer cells.
Cell Death Dis 2014;5():e1551. Epub 2014 des 4
PMID: 25476899
A functional polymorphism C-509T in TGFß-1 promoter contributes to susceptibility and prognosis of lone atrial fibrillation in Chinese population.
PLoS One 2014;9(11):e112912. Epub 2014 nov 17
PMID: 25402477
Adrenocortical carcinoma mimicking lung cancer and responding to vinorelbine/carboplatin and pemetrexed/carboplatin.
BMJ Case Rep 2014;2014(). Epub 2014 nov 12
PMID: 25391823
Icotinib is an active treatment of non-small-cell lung cancer: a retrospective study.
PLoS One 2014;9(5):e95897. Epub 2014 mai 16
PMID: 24836053
TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer.
Cell Death Dis 2014;5():e1055. Epub 2014 feb 13
PMID: 24525731
Preoperative serum receptor activator of nuclear factor-?B ligand/osteoprotegerin predict stabilization of spontaneously restored sinus rhythm in persistent atrial fibrillation patients after mitral valve surgery.
Cardiology 2014;127(3):183-9. Epub 2014 jan 14
PMID: 24434592
Serum sRANKL/OPG predict recurrence after radiofrequency catheter ablation of lone atrial fibrillation.
Int J Cardiol 2014 Jan 1;170(3):298-302. Epub 2013 sep 7
PMID: 24326209
The opposite prognostic significance of nuclear and cytoplasmic p21 expression in resectable gastric cancer patients.
J Gastroenterol 2014 Nov;49(11):1441-52. Epub 2013 okt 15
PMID: 24127074
Effective ultra-low doses of erlotinib in patients with EGFR sensitising mutation.
BMJ Case Rep 2014;2014(). Epub 2014 jul 23
PMID: 25056302
Hidden treasures in "ancient" microarrays: gene-expression portrays biology and potential resistance pathways of major lung cancer subtypes and normal tissue.
Front Oncol 2014;4():251. Epub 2014 sep 29
PMID: 25325012
WT1 promotes cell proliferation in non-small cell lung cancer cell lines through up-regulating cyclin D1 and p-pRb in vitro and in vivo.
PLoS One 2013;8(8):e68837. Epub 2013 aug 1
PMID: 23936312
Preoperative serum soluble receptor activator of nuclear factor-?B ligand and osteoprotegerin predict postoperative atrial fibrillation in patients undergoing cardiac valve surgery.
Ann Thorac Surg 2013 Sep;96(3):800-6. Epub 2013 jul 16
PMID: 23870696
Gefitinib or erlotinib as maintenance therapy in patients with advanced stage non-small cell lung cancer: a systematic review.
PLoS One 2013;8(3):e59314. Epub 2013 mar 21
PMID: 23555654
MDM2 is a useful prognostic biomarker for resectable gastric cancer.
Cancer Sci 2013 May;104(5):590-8. Epub 2013 mar 5
PMID: 23347235
High FAK combined with low JWA expression: clinical prognostic and predictive role for adjuvant fluorouracil-leucovorin-oxaliplatin treatment in resectable gastric cancer patients.
J Gastroenterol 2013 Sep;48(9):1034-44. Epub 2013 jan 11
PMID: 23307041
OPG/RANK/RANKL axis in stabilization of spontaneously restored sinus rhythm in permanent atrial fibrillation patients after mitral valve surgery.
Cardiology 2013;124(1):18-24. Epub 2012 des 28
PMID: 23295350
Molecular resistance fingerprint of pemetrexed and platinum in a long-term survivor of mesothelioma.
PLoS One 2012;7(8):e40521. Epub 2012 aug 8
PMID: 22905093
Prognostic and predictive role of JWA and XRCC1 expressions in gastric cancer.
Clin Cancer Res 2012 May;18(10):2987-96. Epub 2012 mar 27
PMID: 22452940
CHIP functions as a novel suppressor of tumour angiogenesis with prognostic significance in human gastric cancer.
Gut 2013 Apr;62(4):496-508. Epub 2012 apr 25
PMID: 22535373
Leptin attenuates the anti-estrogen effect of tamoxifen in breast cancer.
Biomed Pharmacother 2013 Feb;67(1):22-30. Epub 2012 nov 15
PMID: 23199901
Synergistic Role between p53 and JWA: Prognostic and Predictive Biomarkers in Gastric Cancer.
PLoS One 2012;7(12):e52348. Epub 2012 des 21
PMID: 23285001
Recombinant human endostatin (endostar) decreased recurrent ascites, pleural fluid and ascitic VEGF in a case of advanced mesothelioma.
J Chemother 2012 Aug;24(4):231-6.
PMID: 23040690
Pemetrexed as first or second line in 112 Danish patients. ASCO, Chicago, USA June 2016
J Clin Oncol 34, 2016 (suppl; abstr e20084)
Serum microRNAs/enriched pathways in lung cancer 1-4 years before diagnosis: A pilot study from the HUNT Biobank, Norway
ASCO, Chicago, USA June 2016, J Clin Oncol 34, 2016 (suppl; abstr 11539)
Serum biomarkers in mesothelioma 1-3 years before diagnosis -a pilot study
IMIG Birmingham, UK May 2016
BAP-1 cancer syndrome associated malignancies were not detected among 558 Danish patients with malignant mesothelioma
IMIG, Birmingham, May 2016, UK
Abstract:Postoperative leukopenia is an independent prognostic factor in resectable gastric cancer patients
ASCO 2014
Pathology records of the Aalborg University Hospital reveal 562 cases of Mesothelioma and a 13-fold increase in four decades
European Congress of Pathology 2014
The asbestos industry using world-renowned architects to showcase and increase popularity of asbestos construction materials.
IMIG 2014
“Hunting” for lung-cancer / mesothelioma early biomarkers: results of a pilot analysis from the Cancer-Biomarker-HUNT study.
IMIG 2014
Mesothelioma in women in the Region of North Jutland, Denmark; Non-Occupational asbestos exposure in more than 50% of the cases.
IMIG 2014
Overrepresentation of malignant peritoneal mesothelioma among females in a cohort of 296 Danish patients
IMIG 2014
Asbestos textile production linked to malignant mesothelioma in women: Analysis of 28 cases in Southeast China
IMIG 2014
Asbestos Cancer and Biomarker HUNT
Oral presentation, 3rd World Congress on Cancer Science and Therapy
DNA repair suppression and effect of cisplatin in mesothelioma and lung cancer cell lines.
J Clin Oncol 31, 2013 (suppl; abstr e13542)
Comparative evaluation of Affymetrix and Illumina genome-wide expression data in Pleural Mesothelioma
Proceedings of the 7th conference of the Hellenic Society for Computational Biology & Bioinformatics - HSCBB12 FORTH, Heraklion, Crete, Greece, 4-6/10/2012
Differentially expressed genes of major lung tumour subtypes and normal lung tissue.
Proceedings of the 7th conference of the Hellenic Society for Computational Biology & Bioinformatics - HSCBB12 FORTH, Heraklion, Crete, Greece, 4-6/10/2012
Mesothelioma cluster in a medium sized hospital in South-East China: Relations to asbestos exposure and clinicopathological find
IMIG, Boston, USA, 2012
Cell cycle checkpoint genes and homologous recombinational repair are overexpressed in malignant pleural mesothelioma
IMIG2012, Boston, USA
Fanconi anemia genes, RHINO and other cell cycle checkpoint genes are overexpressed in malignant pleural mesothelioma
The 3rd Erling Seeberg symposium, June 2012 in Trondheim and Ørland
- Mogens Vyberg Prosjektdeltaker
- Jianwei Zhou Prosjektdeltaker
- Ioannis Tsamardinos Prosjektdeltaker
- Frank Skorpen Prosjektdeltaker
- Pål Sætrom Prosjektdeltaker
- Kristian Hveem Prosjektdeltaker
- Hans Einar Krokan Hovedveileder
- Oluf Dimitri Røe Postdoktorstipendiat
- Larsson Erik Prosjektdeltaker
- Duan Chen Prosjektdeltaker
- Erik Larsson Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Helse Midt-Norge RHF - Samarbeidsorganet og FFU