Modifications of DNA double stand break repair genes and risk of neurological and immune system disorders
- Prosjektnummer
- 90061800
- Ansvarlig person
- Valentyn Oksenych
- Institusjon
- NTNU, IKOM
- Prosjektkategori
- Forskerstipend
- Helsekategori
- Inflammatory and Immune System
- Forskningsaktivitet
- 2. Aetiology
Synthetic lethality between DNA repair factors Xlf and Paxx is rescued by inactivation of Trp53.
DNA Repair (Amst) 2019 01;73():164-169. Epub 2018 des 16
PMID: 30579708
Mediator of DNA Damage Checkpoint Protein 1 Facilitates V(D)J Recombination in Cells Lacking DNA Repair Factor XLF.
Biomolecules 2019 Dec 30;10(1). Epub 2019 des 30
PMID: 31905950
Generation of a Mouse Model Lacking the Non-Homologous End-Joining Factor Mri/Cyren.
Biomolecules 2019 Nov 28;9(12). Epub 2019 nov 28
PMID: 31795137
Genetic interaction between DNA repair factors PAXX, XLF, XRCC4 and DNA-PKcs in human cells.
FEBS Open Bio 2019 07;9(7):1315-1326. Epub 2019 jun 12
PMID: 31141305
Robust DNA repair in PAXX-deficient mammalian cells.
FEBS Open Bio 2018 03;8(3):442-448. Epub 2018 feb 7
PMID: 29511621
Normal development of mice lacking PAXX, the paralogue of XRCC4 and XLF.
FEBS Open Bio 2018 03;8(3):426-434. Epub 2018 feb 4
PMID: 29511619
Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70.
DNA Repair (Amst) 2017 Sep;57():133-138. Epub 2017 jul 26
PMID: 28759779
Normal development of mice lacking PAXX, the paralogue of XRCC4 and XLF
FEBS Open Bio, 2018
Robust DNA repair in PAXX‐deficient mammalian cells
FEBS Open Bio, 2018
Genetisk samspill mellom ikke-homologe sammenføyningsfaktorer i mus og mennesker
- Disputert:
- april 2019
- Hovedveileder:
- Valentyn Oksenych
- Valentyn Oksenych Prosjektleder
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Helse Midt-Norge RHF - Samarbeidsorganet og FFU