Multiple Sclerosis. Gene Expression Profiling of Histopathological and Clinical heterogeneity
- Prosjektnummer
- 911109
- Ansvarlig person
- Lars Bø
- Institusjon
- Helse Bergen HF
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Neurology
- Forskningsaktivitet
- Translasjonsforskning
Spinal cord grey matter lesions in multiple sclerosis detected by post-mortem high field MR imaging.
Mult Scler 2009 Feb;15(2):180-8. Epub 2008 okt 9
PMID: 18845658
Regional variations in the extent and pattern of grey matter demyelination in multiple sclerosis: a comparison between the cerebral cortex, cerebellar cortex, deep grey matter nuclei and the spinal cord.
J Neurol Neurosurg Psychiatry 2009 Feb;80(2):182-7. Epub 2008 okt 1
PMID: 18829630
The cuprizone model for demyelination.
Acta Neurol Scand Suppl 2008;188():72-6.
PMID: 18439226
Mast cell transcripts are increased within and outside multiple sclerosis lesions.
J Neuroimmunol 2008 Mar;195(1-2):176-85. Epub 2008 mar 28
PMID: 18374990
Homogeneity of active demyelinating lesions in established multiple sclerosis.
Ann Neurol 2008;63(1):16-25.
PMID: 18232012
Does high-field MR imaging improve cortical lesion detection in multiple sclerosis?
J Neurol 2008 Feb;255(2):183-91. Epub 2008 feb 4
PMID: 18231704
CCL5 and CCR5 genotypes modify clinical, radiological and pathological features of multiple sclerosis.
J Neuroimmunol 2007 Oct;190(1-2):157-64. Epub 2007 sep 19
PMID: 17884183
Downregulation of macrophage inhibitory molecules in multiple sclerosis lesions.
Ann Neurol 2007 Nov;62(5):504-14.
PMID: 17879969
Extensive hippocampal demyelination in multiple sclerosis.
J Neuropathol Exp Neurol 2007 Sep;66(9):819-27.
PMID: 17805012
The blood-brain barrier in cortical multiple sclerosis lesions.
J Neuropathol Exp Neurol 2007 Apr;66(4):321-8.
PMID: 17413323
Lack of correlation between cortical demyelination and white matter pathologic changes in multiple sclerosis.
Arch Neurol 2007 Jan;64(1):76-80.
PMID: 17210812
Grey matter pathology in multiple sclerosis.
Acta Neurol Scand Suppl 2006;183():48-50.
PMID: 16637929
Growth-associated protein 43 in lesions and cerebrospinal fluid in multiple sclerosis.
Neuropathol Appl Neurobiol 2006 Jun;32(3):318-31.
PMID: 16640650
NAD(P)H:quinone oxidoreductase 1 expression in multiple sclerosis lesions.
Free Radic Biol Med 2006 Jul;41(2):311-7. Epub 2006 apr 26
PMID: 16814112
Spinal cord gray matter demyelination in multiple sclerosis-a novel pattern of residual plaque morphology.
Brain Pathol 2006 Jul;16(3):202-8.
PMID: 16911477
Extensive extracellular matrix depositions in active multiple sclerosis lesions.
Neurobiol Dis 2006 Dec;24(3):484-91. Epub 2006 sep 26
PMID: 17005408
Expression patterns of Group III metabotropic glutamate receptors mGluR4 and mGluR8 in multiple sclerosis lesions.
J Neuroimmunol 2005 Jan;158(1-2):182-90.
PMID: 15589052
The pathology of multiple sclerosis is location-dependent: no significant complement activation is detected in purely cortical lesions.
J Neuropathol Exp Neurol 2005 Feb;64(2):147-55.
PMID: 15751229
Cortical lesions in multiple sclerosis: combined postmortem MR imaging and histopathology.
AJNR Am J Neuroradiol 2005 Mar;26(3):572-7.
PMID: 15760868
Blood-brain barrier alterations in both focal and diffuse abnormalities on postmortem MRI in multiple sclerosis.
Neurobiol Dis 2005 Dec;20(3):953-60. Epub 2005 jul 21
PMID: 16039866
Basement membrane proteins in multiple sclerosis-associated inflammatory cuffs: potential role in influx and transport of leukocytes.
J Neuropathol Exp Neurol 2005 Aug;64(8):722-9.
PMID: 16106221
Imaging the optic nerve in multiple sclerosis.
Mult Scler 2005 Oct;11(5):537-41.
PMID: 16193891
Imaging spinal cord damage in multiple sclerosis.
J Neuroimaging 2005 Oct;15(4):297-304.
PMID: 16254392
Spinal cord atrophy in multiple sclerosis caused by white matter volume loss.
Arch Neurol 2005 Dec;62(12):1859-62.
PMID: 16344343
Magnetic resonance imaging as a tool to examine the neuropathology of multiple sclerosis.
Neuropathol Appl Neurobiol 2004 Apr;30(2):106-17.
PMID: 15043708
Extensive myelin protein deposition in the meninges of patients with multiple sclerosis
Multiple Sclerosis 14:S273, 2008
Meningeal inflammation in multiple sclerosis
Multiple Sclerosis 14: S273, 2008
Homogeneity of active demyelinating lesions in patients with eastablished multiple sclerosis
Multiple Sclerosis 14:S9, 2008
Secondary progressive multiple sclerosis has more axonal loss in the spinal cord than primary progressive
Journal of Neurology Neurosurgery and Psychiatry 78 (9):1033, 2007
Addressing the enigma of invisible pathology in multiple sclerosis. A multimodal approach to characterise diffusely abnormal WM
Multiple Sclerosis 13:S77, 2007
Extensive hippocampal demyelination in multiple sclerosis
Multiple Sclerosis 13:S141, 2007
Primary progressive MS shows different axonal and demyelinating pathology compared to secondary progressive disease
Multiple Sclerosis 13:S106, 2007
Spinal cord gray matter is a predilection site for demyelination in multiple sclerosis
Neurology 2006 66 (5): A374-A374 Suppl. 2
Spinal cord grey matter is a predilection site for demyelination in multiple sclerosis
Journal of Neurology, Neurosurgery and Psychiatry 77(12): 1389-1389, 2006
Real time RF-PCR reveals increased mast cell transcripts in MS lesions
Clinical Immunology 119: S115, Suppl S, 2006
Sensitivity of high resolution MRI for detecting grey matter demyelination in the spinal cord in multiple sclerosis: A postmorte
Journal of Neurology, Neurosurgery and Psychiatry 77 (1): 130. 2006.
Evidence of substantial spinal cord neuronal pathology in multiple sclerosis
Multiple Sclerosis, 9 2006; vol. 12: pp. S2
Regional variation in the extent and pattern of grey matter demyelination in multiple sclerosis: a pathological comparison betwe
Multiple Sclerosis, 9 2006; vol. 12: pp. S20.
Cross-linking pathological, radiological and clinical subgroups in multiple sclerosis: building a genetic bridge
Multiple Sclerosis, 9 2006; vol. 12: pp. S226.
Imaging cortical lesions and NAGM at high and standard field-strength (4.7T and 1.5T): combined post-mortem MRI and histopatholo
ECTRIMS, Multiple Sclerosis 2005 11: S8-S9 Suppl. 1.
Homogenous MS lesion pathology in unselected autopsy material.
ECTRIMS, Multiple Sclerosis 2005 11: S42-S42 Suppl. 1
General subpial cortical demyelination in multiple sclerosis
ECTRIMS, Multiple Sclerosis 2005 11: S42-S42 Suppl. 1
CCR5 and CCL5 genes, perivascular leukocyte infiltration, and disease course in MS patients
ECTRIMS, Multiple Sclerosis 2005 11: S115-S115 Suppl. 1
Sensitivity of high-resolution MRI for detecting grey matter demyelination in the spinal cord in multiple sclerosis: a post-mort
ECTRIMS, Multiple Sclerosis 2005 11: S149-S149 Suppl. 1
Extensive grey matter demyelination occurs in the spinal cord in multiple sclerosis.
ECTRIMS, Multiple Sclerosis 2005 11: S179-S179 Suppl. 1
Gray Matter Pathology in Multiple Sclerosis
Filippi M, Comi G, Rovaris M (eds) Normal-appearing White and Grey Matter Damage in Multiple Sclerosis. Springer Verlag 2004
Complement, immunoglobulins and Fc gamma receptors associated with macrophages in active demyelinating multiple sclerosis lesion
Molecular Immunology (2-3): 214-215 29 JUN 2004
Deposition of complement, immunoglobulins and Fcγ receptors within macrophages in active demyelinating Multiple Sclerosis l
XXth International complement workshop 2004
Increased expression of axonal growth associated protein 43 (GAP-43) expression at the border of Multiple Sclerosis lesions
International Congress of Neuroimmunology, International Society of Neuroimmunology 2004
Increased expression of axonal growth associated protein 43 (GAP-43) expression at the border of Multiple Sclerosis lesions
FENS 2004
Spinal cord atrophy: It’s all in the white matter
European Committee of Treatment and Research in MS, ECTRIMS 2004
Absence of Fibrinogen and IgG Leakage in Cortical Multiple Sclerosis Lesions
ECTRIMS 2004
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Faglig rapportering, Helse Vest