Kuldeindusert mikrovaskulær lekkasje med organaffeksjon:Tiltak for minimalisering av organskade / dysfunksjon (hjerne/hjerte)
- Prosjektnummer
- 911226
- Ansvarlig person
- Paul Husby
- Institusjon
- Universitetet i Bergen
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Cardiac & Cardiovascular Systems
- Forskningsaktivitet
- Translasjonsforskning
A hyperosmolar-colloidal additive to the CPB-priming solution reduces fluid load and fluid extravasation during tepid CPB.
Perfusion 2008 Jan;23(1):57-63.
PMID: 18788219
Surface cooling versus core cooling: comparative studies of microvascular fluid- and protein-shifts in a porcine model.
Resuscitation 2008 Nov;79(2):292-300. Epub 2008 jul 24
PMID: 18656301
Fluid overload during cardiopulmonary bypass is effectively reduced by a continuous infusion of hypertonic saline/dextran (HSD).
Scand Cardiovasc J 2008 Feb;42(1):63-70.
PMID: 17896202
Low perfusion pressure during CPB may induce cerebral metabolic and ultrastructural changes.
Scand Cardiovasc J 2007 Oct;41(5):331-8.
PMID: 17852788
Elevated flow rate during cardiopulmonary bypass is associated with fluid accumulation.
J Thorac Cardiovasc Surg 2007 Sep;134(3):587-93.
PMID: 17723803
Mean arterial pressure about 40 mmHg during CPB is associated with cerebral ischemia in piglets.
Scand Cardiovasc J 2006 Feb;40(1):54-61.
PMID: 16448999
Reduced fluid gain during cardiopulmonary bypass in piglets using a continuous infusion of a hyperosmolar/hyperoncotic solution.
Acta Anaesthesiol Scand 2006 Aug;50(7):855-62.
PMID: 16879469
Time course variations of haemodynamics, plasma volume and microvascular fluid exchange following surface cooling: an experimental approach to accidental hypothermia.
Resuscitation 2005 May;65(2):211-9. Epub 2005 jan 25
PMID: 15866403
Fluid shift is moderate and short-lived during acute crystalloid hemodilution and normothermic cardiopulmonary bypass in piglets.
Acta Anaesthesiol Scand 2005 Aug;49(7):949-55.
PMID: 16045655
Cold-induced fluid extravasation during cardiopulmonary bypass in piglets can be counteracted by use of iso-oncotic prime.
J Thorac Cardiovasc Surg 2005 Aug;130(2):287-94.
PMID: 16077389
Low arterial pressure during cardiopulmonary bypass in piglets does not decrease fluid leakage.
Acta Anaesthesiol Scand 2005 Oct;49(9):1255-62.
PMID: 16146461
Cold-induced changes in plasma volume (PV) and microvascular permeability: The effect of insulin administration.
Intensive Care Med 2008: 34(suppl.1)p.188: 0732
Surface cooling versus core cooling: comparative studies on microvascular fluid and protein shifts in a porcine model
Intensiv Care med 2008; p188: 0734
Intraoperative fluid balance suring cardiopulmonary bypass: effects of different mean arterial pressures
Perfusion 2007; 22: 273-278
Reduction of fluid needs during CPB in piglets by a continuous infusion of hypertonic saline / HES
Eur J Anaesth 2006; A174.
Effect of different perfusion pressures on cerebral energy metabolism and ultrastructure during CPB in pigs.
Intensive Care Med 2006; 32: pS7
Reduced fluid gain during CPB in piglets by use of an infusion of a hypertonic-hyperoncotic solution.
Intensive Care Med 2006; 32: pS115
Fluid Management during the treatment of immersion hypothermia
Handbook on Drowning - Prevention, Rescue and Treatment. (Bierens J. et aL., eds.) Springer Verlag, August 2005, Heidelberg, Germany
Mean arterial pressure about 40 mm Hg during CPB is associated with cerebral ischemia in piglets
Scandinavian Cardiovasc J 2005: http://www.journalsonline.tandf.co.uk/(0czixgikjlsc4f45ruo00555)/app/home/contribution.asp?referrer=parent&backto=issue,8,10;journal,1,53;linkingpublicationresults,1:101947,1
Cerebral ischemia during low-pressure cardiopulmonary bypass in piglets
Proceedings of SATS-meeting, 2005 (Scandinavian Association of Thoracic Surgeons)
Cerebral ischemia during low-pressure cardiopulmonary bypass in piglets
J Intensive Care 2005; 31(suppl. 1): O57
Effects of different mean arterial pressures and machine flow rates on fluid extravasation during normothermic CPB
Proceedings of the SATS-and SCANSECT-meeting 2005; p 98: O23
Interventions on arterial pressure and perfusion flow rate during cardiopulmonary bypass: Effects on global fluid shifts, .....
- Disputert:
- januar 2008
- Hovedveileder:
- Paul Husby
Fluid extravasation and edema preventing interventions during normothermic and hypothermic cardiopulmonary bypass (CPB)
- Disputert:
- mai 2006
- Hovedveileder:
- Paul Husby
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Faglig rapportering, Helse Vest