Subklassifikasjon og molekylær monitorering av behandling av pasienter med AML
- Prosjektnummer
- 911227
- Ansvarlig person
- Karl-Henning Kalland
- Institusjon
- Universitetet i Bergen
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Hematology
- Forskningsaktivitet
- Translasjonsforskning
Functional characteristics and gene expression profiles of primary acute myeloid leukaemia cells identify patient subgroups that differ in susceptibility to histone deacetylase inhibitors.
Int J Oncol 2007 Dec;31(6):1529-38.
PMID: 17982680
Release of angiopoietin-1 by primary human acute myelogenous leukemia cells is associated with mutations of nucleophosmin, increased by bone marrow stromal cells and possibly antagonized by high systemic angiopoietin-2 levels.
Leukemia 2008 Feb;22(2):287-93. Epub 2007 okt 18
PMID: 17943167
Hyperoxia retards growth and induces apoptosis, changes in vascular density and gene expression in transplanted gliomas in nude rats.
J Neurooncol 2007 Nov;85(2):191-202. Epub 2007 jun 8
PMID: 17557137
Early gene expression of acute myeloid leukemia in response to chemotherapy.
Expert Rev Anticancer Ther 2007 May;7(5):741-51.
PMID: 17492937
Comparison of nucleic acid targets prepared from total RNA or poly(A) RNA for DNA oligonucleotide microarray hybridization.
Anal Biochem 2007 Jul;366(1):46-58. Epub 2007 mar 18
PMID: 17449007
Subclassification of patients with acute myelogenous leukemia based on chemokine responsiveness and constitutive chemokine release by their leukemic cells.
Haematologica 2007 Mar;92(3):332-41.
PMID: 17339182
Increased expression of SIM2-s protein is a novel marker of aggressive prostate cancer.
Clin Cancer Res 2007 Feb;13(3):892-7.
PMID: 17289882
ERG upregulation and related ETS transcription factors in prostate cancer.
Int J Oncol 2007 Jan;30(1):19-32.
PMID: 17143509
cDNA microarray analysis of non-selected cases of acute myeloid leukemia demonstrates distinct clustering independent of cytogenetic aberrations and consistent with morphological signs of differentiation.
Int J Oncol 2006 May;28(5):1065-80.
PMID: 16596222
Stress-induced in vitro apoptosis of native human acute myelogenous leukemia (AML) cells shows a wide variation between patients and is associated with low BCL-2:Bax ratio and low levels of heat shock protein 70 and 90.
Leuk Res 2006 Dec;30(12):1531-40. Epub 2006 apr 5
PMID: 16600371
A distinct p53 protein isoform signature reflects the onset of induction chemotherapy for acute myeloid leukemia.
Clin Cancer Res 2006 Jul;12(13):3985-92.
PMID: 16818696
Angiogenesis-independent tumor growth mediated by stem-like cancer cells.
Proc Natl Acad Sci U S A 2006 Oct;103(44):16466-71. Epub 2006 okt 20
PMID: 17056721
CD34 expression in native human acute myelogenous leukemia blasts: differences in CD34 membrane molecule expression are associated with different gene expression profiles.
Cytometry B Clin Cytom 2005 Mar;64(1):18-27.
PMID: 15668952
[Nucleic-acid based diagnostics in clinical microbiology]
Tidsskr Nor Laegeforen 2005 Nov;125(22):3110-4.
PMID: 16299567
Release of angiopoietin-1 by acute myelogenous leukemia (AML) cells is increased by stromal cells and associated with mutations
Experimental Hematology 2007;35(9) Suppl 2:72-72
Functional characteristics and gene expression profiles of primary acute myeloid leukaemia cells identify patient subgroups that
Haematologica 2007;92 Suppl 1:112-112
Linking susceptibility to histone deactylase inhibitors and basal gene expression profiles in acute myeloid leukaemia.
Experimental Hematology 2007;35(9):77-77
Early gene expression signature of chemotherapy treated acute myeloid leukemia in vivo
AACR Annual Meeting 2007; 14.04.2007 - 18.04.2007
Global gene expression in classification, pathogenetic understanding and identification of therapeutic targets in acute myeloid
Current Pharm. Biotechnol. 8: 344-354, 2007
Virus og Kreft
Naturen 3: 133 - 145, 2006
cDNA microarray analysis of non-selected cases of acute myeloid leukemia demonstrates distinct clustering independent of cytogen
NBS-nytt 2006;1 Suppl 1:106
ERG upregulation in relation to other transcription factors in prostate cancer
NBS-nytt 2006;1 Suppl 1:72
The early gene expression signature of AML blasts during in vivo chemotherapy
Int. J. Oncol. 18, suppl. 1: S65, 2006
Global gene expression analysis of transcription factors in prostate cancer and cell lines
Int. J. Oncol.18, suppl. 1: S27, 2006
Discovering candidate genes that distinguish between CML and AML using microarrays
Norwegian Biochemical Society Contact Meeting Jan 13-16 2005 - Tromsø
Analysis of treatment response in AML patients using DNA microarrays.
Norwegian Biochemical Society Contact Meeting Jan 13-16 2005 - Tromsø
cDNA microarray analysis of non-selected cases of acute myeloid leukemia demonstrates distinct clustering independent of cytogen
The Norwegian Biochemical Society 42. Contact Meeting - Storefjell, Norway Jan. 19. - 22. 2005
cDNA microarray analysis of non-selected cases of acute myeloid leukemia demonstrates distinct clustering independent of cytogen
Int. J. Oncol. 2006, in press.
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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