Chronic Inflammation and Fibrosis of the Kidney in Hypertension
- Prosjektnummer
- 911322
- Ansvarlig person
- Michael Hultstrøm
- Institusjon
- Universitetet i Bergen
- Prosjektkategori
- Forskerutdanning - dr.grad
- Helsekategori
- Renal and Urogenital
- Forskningsaktivitet
- 1. Underpinning
Adenosine sensitization after angiotensin II stimulation in afferent arterioles from normal rats does not occur during two-kidney, one-clip hypertension.
Acta Physiol (Oxf) 2011 Feb;201(2):289-94.
PMID: 20698832
AT(1) receptor activation regulates the mRNA expression of CAT1, CAT2, arginase-1, and DDAH2 in preglomerular vessels from angiotensin II hypertensive rats.
Am J Physiol Renal Physiol 2009 Jul;297(1):F163-8. Epub 2009 apr 22
PMID: 19386725
Angiotensin II-induced contraction is attenuated by nitric oxide in afferent arterioles from the nonclipped kidney in 2K1C.
Am J Physiol Renal Physiol 2009 Jan;296(1):F78-86. Epub 2008 okt 22
PMID: 18945823
Sympathectomy suppresses tumor growth and alters gene-expression profiles in rat tongue cancer.
Eur J Oral Sci 2009 Aug;117(4):351-61.
PMID: 19627344
Tetradecylthioacetic acid downregulates cyclooxygenase 2 in the renal cortex of two-kidney, one-clip hypertensive rats.
Am J Physiol Regul Integr Comp Physiol 2008 Dec;295(6):R1866-73. Epub 2008 okt 8
PMID: 18843091
Upregulation of tissue inhibitor of metalloproteases-1 (TIMP-1) and procollagen-N-peptidase in hypertension-induced renal damage.
Nephrol Dial Transplant 2008 Mar;23(3):896-903. Epub 2007 okt 31
PMID: 17977875
Trefoil factor-3 is down regulated while CYP24a1 is increased in the ageing rat kidney.
Experimental Biology in Anaheim 2010.
Osteopontin is upregulated in damaged non-clipped kidney cortex from rats with renal hypertension
Experimental Biology in Anaheim 2010.
Increased decorin mRNA expression leads to larger collagen fibril diameter in SHR kidney cortex.
Experimental Biology in Anaheim 2010.
Juxtamedullary cortex is subjected to a higher degree of renal damage than the outer cortex in the non-clipped kidney in two kid
20th meeting of the European Society of Hypertension, Oslo 2010.
Hypertensive renal damage is not ageing: Evidence from global gene expression in rat renal cortex.
20th meeting of the European Society of Hypertension, Oslo 2010.
Renal vascular L-arginine metabolism in Angiotensin II induced nitric oxide synthesis after uninephrectomy.
FASEB summer research conference: “Renal Hemodynamics: Mechanisms to understand disease”, Saxtons River, Vermont, 2010.
The increased nitric oxide synthesis in afferent arterioles from the remaining kidney early after uninephrectomy depends on cell
Manuskript som ingår i avhandlingen
Compensatory hyperfiltration and NO in 2k1c and uninephrectomised rats,
Biology in San Diego 2008. Poster presentation by Michael Hultström.
Collagen metabolism and renal damage in 2k1c hypertensive rats.
Experimental Biology in San Diego 2008. Poster presentation by Trude Skogstrand
Angiotensin II regulates the mRNA expression of enzymes involved in arginine metabolism in isolated renal resistance vessels thr
SPS annual meeting, Oulu, 2008. Oral Presentation by Michael Hultström.
Protein expression of factors involved in the development of renal interstitial fibrosis in old SHR
Abstract at Experimenytal Biology 2007, The FASEB Journal. 2007;21:755.12
The mRNA expression of eNOS, iNOS and L-arginine transporters in the afferent arterioles (AA) of 2K1C hypertensive rats
Abstract at Experimental Biology 2007, The FASEB Journal. 2007;21:755.13
Angiotensin II in hypertension, renal damage and renal vascular function
- Disputert:
- august 2010
- Hovedveileder:
- Bjarne Iversen
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Faglig rapportering, Helse Vest