Endocrine treatment of breast cancer. Predictors of treatment outcome and tailored therapy
Prognostic significance of Ki-67 labeling index after short-term presurgical tamoxifen in women with ER-positive breast cancer.
Ann Oncol 2011 Mar;22(3):582-7. Epub 2010 aug 17
Functional polymorphisms in UDP-glucuronosyl transferases and recurrence in tamoxifen-treated breast cancer survivors.
Cancer Epidemiol Biomarkers Prev 2011 Sep;20(9):1937-43. Epub 2011 jul 12
Efficacy of tamoxifen based on cytochrome P450 2D6, CYP2C19 and SULT1A1 genotype in the Italian Tamoxifen Prevention Trial.
Pharmacogenomics J 2011 Apr;11(2):100-7. Epub 2010 mar 23
Associations between tamoxifen, estrogens, and FSH serum levels during steady state tamoxifen treatment of postmenopausal women with breast cancer.
BMC Cancer 2010;10():313. Epub 2010 jun 21
Effect of low-dose tamoxifen on steroid receptor coactivator 3/amplified in breast cancer 1 in normal and malignant human breast tissue.
Clin Cancer Res 2010 Apr;16(7):2176-86. Epub 2010 mar 23
Randomized biomarker trial of anastrozole or low-dose tamoxifen or their combination in subjects with breast intraepithelial neoplasia.
Clin Cancer Res 2009 Nov;15(22):7053-60. Epub 2009 nov 3
Randomized double-blind 2 x 2 trial of low-dose tamoxifen and fenretinide for breast cancer prevention in high-risk premenopausal women.
J Clin Oncol 2009 Aug;27(23):3749-56. Epub 2009 jul 13
Genotype-guided tamoxifen therapy: time to pause for reflection?
Lancet Oncol 2009 Aug;10(8):825-33.
Nuclear receptor co-activators and HER-2/neu are upregulated in breast cancer patients during neo-adjuvant treatment with aromatase inhibitors.
Br J Cancer 2009 Oct;101(8):1253-60. Epub 2009 sep 15
Tamoxifen impairs both longitudinal and cortical bone growth in young male rats.
J Bone Miner Res 2008 Aug;23(8):1267-77.
Effects of CYP2D6 and SULT1A1 genotypes including SULT1A1 gene copy number on tamoxifen metabolism.
Ann Oncol 2008 Jan;19(1):56-61. Epub 2007 okt 18
Recruitment of coactivator glucocorticoid receptor interacting protein 1 to an estrogen receptor transcription complex is regulated by the 3',5'-cyclic adenosine 5'-monophosphate-dependent protein kinase.
Endocrinology 2008 Sep;149(9):4336-45. Epub 2008 mai 22
Randomized dose-ranging trial of tamoxifen at low doses in hormone replacement therapy users.
J Clin Oncol 2007 Sep;25(27):4201-9. Epub 2007 aug 20
Steroid receptor coactivators and their expression, regulation and functional role in endocrine responsive and resistant breast
Breast cancer cells, editor Gunduz M. InTech Open Access Publisher, ISBN 978-953-307-351-4, Rijeka, Croatia.
Steroid receptor coactivators and endocrine treatment in breast cancer.
In: Nuclear Receptors: Structure, mechanisms of action and disease, editors Bates MK and Kerr RM, pp. 35-66. Nova Publishers Inc, ISBN 978-61209-980-4, New York, USA.
Mastergrad: Farmasi, "Tamoxifen treatment of breast cancer cells. Pharmacodynamic study by gene expresssion analysis"
Universitetet i Bergen
Pharmacogenetics and personalized tamoxifen treatment.
The EORTC PAMM group 31th Winter Meeting”, Toulouse, Frankrike, 2010
CYP2C19 single nucleotide polymorphisms And their effects on the metabolism of Tamoxifen in breast cancer patients.
Universitetet i Bergen 2010
Expression of Steroid Receptor Coactivators and HER-2/neu in normal and malignant breast tissue in controls and tamoxifen treate
AACR Annual Meeting; 2010-04-17 - 2010-04-21
Effects of CYP2C19 genotype on tamoxifen and estrogen metabolism.
21st European Association for Cancer Research conference; 2010
The influence of tamoxifen treatment on the expression levels of liver receptor homolog (LHR-1).
2010-06-26 - 2010-06-29
Distribution of tamoxifen and five metabolites into normal and malignant human breast cancer tissue during conventional and low
33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium; 2010-12-08 - 2010-12-12
Hormoner og hormonantagonister
Effect of CYP2D6 and SULT1A1 Genotypes on the serum concentration of 4-OHtamoxifen and 4-OH-N-Demethyltamoxifen during steady st
The Breast. 16; S15, 2007.
Effects of CYP2D6 and SULT1A1 genotypes including SULT1A1 gene copy number on tamoxifen metabolism
A study of associations between estrogen and tamoxifen metabolism, cytochrome 2D6 and sulfotransferase 1A1 polymorphisms, and su
Breast Cancer Res. Treat. 106; S144, 2007
Steroid receptor coactivators and epidermal growth factor receptors in breast cancer
- mars 2011
- Gunnar Mellgren
Pharmacogenetics and therapeutic drug monitoring
- juni 2008
- Ernst Lien
Regulation of Nuclear Receptor Coactivator GRIP1 by cAMP-Dependent Signaling
- oktober 2008
- Gunnar Mellgren
Nuclear receptor coregulators – Role of protein-protein interactions and cAMK/PKA signaling.
- februar 2007
- Gunnar Mellgren