Growth factor signalling and nuclear receptor coactivators in breast cancer
- Prosjektnummer
- 911568
- Ansvarlig person
- Gunnar Mellgren
- Institusjon
- Helse Bergen HF
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Cancer
- Forskningsaktivitet
- 2. Aetiology
Serum concentrations of tamoxifen and its metabolites increase with age during steady-state treatment.
Breast Cancer Res Treat 2013 Sep;141(2):243-8. Epub 2013 sep 1
PMID: 23996142
cAMP response element-binding protein interacts with and stimulates the proteasomal degradation of the nuclear receptor coactivator GRIP1.
Endocrinology 2013 Apr;154(4):1513-27. Epub 2013 mar 5
PMID: 23462962
Downregulation of steroid receptor coactivator-2 modulates estrogen-responsive genes and stimulates proliferation of mcf-7 breast cancer cells.
PLoS One 2013;8(7):e70096. Epub 2013 jul 30
PMID: 23936147
Inverse regulation of EGFR/HER1 and HER2-4 in normal and malignant human breast tissue.
PLoS One 2013;8(8):e74618. Epub 2013 aug 22
PMID: 23991224
Tissue distribution of 4-hydroxy-N-desmethyltamoxifen and tamoxifen-N-oxide.
Breast Cancer Res Treat 2012 Jul;134(2):693-700. Epub 2012 mai 5
PMID: 22562123
Steroid receptor coactivators, HER-2 and HER-3 expression is stimulated by tamoxifen treatment in DMBA-induced breast cancer.
BMC Cancer 2012;12():247. Epub 2012 jun 15
PMID: 22703232
Efficacy of tamoxifen based on cytochrome P450 2D6, CYP2C19 and SULT1A1 genotype in the Italian Tamoxifen Prevention Trial.
Pharmacogenomics J 2011 Apr;11(2):100-7. Epub 2010 mar 23
PMID: 20309015
Associations between tamoxifen, estrogens, and FSH serum levels during steady state tamoxifen treatment of postmenopausal women with breast cancer.
BMC Cancer 2010;10():313. Epub 2010 jun 21
PMID: 20565970
Effect of low-dose tamoxifen on steroid receptor coactivator 3/amplified in breast cancer 1 in normal and malignant human breast tissue.
Clin Cancer Res 2010 Apr;16(7):2176-86. Epub 2010 mar 23
PMID: 20332317
Inverse regulation of Neuregulin1 and HER-3 during treatment with aromatase inhibitors of estrogen receptor-pos. breast cancer
San Antonio Breast Cancer symposium, 2012, P6-04-06
Characterization of Global Gene Expression in Breast Cancer Cells after cAMP/PKA-mediated downregulation of Steroid Receptor Coa
Nuclear receptors: From Molecular Mechanism to Health and Disease; 2011-09-16
The nuclear receptor coactivator PELP1/MNAR is positively correlated with estrogen levels in breast cancer patients
Nuclear receptors - from molecular mechanisms to health and disease; 2011-09-16
Steroid Receptor Coactivators and Endocrine Treatment in Breast Cancer
Nuclear Receptors. Nova Science Publishers, Inc. 2011 ISBN 978-1-61209-980-4. s. 35-66
Steroid Receptor Coactivators and Their Expression, Regulation and Functional Role in Endocrine Responsive and Resistant Breast
Breast Cancer - Carcinogenesis, Cell Growth and Signalling Pathways. INTECH 2011 ISBN 978-953-307-714-7. s. 715-732
Epidermal growth factor receptors (ErbB/HER) and the ligand Neuregulin 1 (NRG1) increase in breast tumors during..
33rd annual San Antonio breast cancer symposium; 2010-12
Expression of Steroid Receptor Coactivators and HER-2/neu in normal and malignant breast tissue in controls and tamoxifen..
AACR Annual Meeting; 2010-04-17
Endocrine treatment of breast cancer Tamoxifen metabolism, steroid receptor coactivators and growth factor receptors
- Disputert:
- januar 2012
- Hovedveileder:
- Gunnar Mellgren
Steroid receptor coactivators and epidermal growth factor receptors in breast cancer
- Disputert:
- april 2011
- Hovedveileder:
- Gunnar Mellgren og Ernst A. Lien
- Per Eystein Lønning Prosjektdeltaker
- Gunnar Mellgren Prosjektleder
- Ernst Asbjørn Lien Prosjektdeltaker
- Ingvild Sveinsgjerd Fenne Postdoktor
- Marianne Flågeng Postdoktor
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Faglig rapportering, Helse Vest