Iron and calcium homeostasis in the brain and its impact on Parkinson's Disease
- Prosjektnummer
- 911630
- Ansvarlig person
- Simon Geir Møller
- Institusjon
- Helse Stavanger HF
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Neurological
- Forskningsaktivitet
- 1. Underpinning, 4. Detection and Diagnosis
Association of a BACE1 Gene Polymorphism with Parkinson's Disease in a Norwegian Population.
Parkinsons Dis 2015;2015():973298. Epub 2015 des 14
PMID: 26788404
A Proteomics Approach to Investigate miR-153-3p and miR-205-5p Targets in Neuroblastoma Cells.
PLoS One 2015;10(12):e0143969. Epub 2015 des 3
PMID: 26633009
microRNAs as neuroregulators, biomarkers and therapeutic agents in neurodegenerative diseases.
Cell Mol Life Sci 2015 Nov 25. Epub 2015 nov 25
PMID: 26608596
The Potential of Proteomics in Understanding Neurodegeneration.
Int Rev Neurobiol 2015;121():25-58. Epub 2015 jun 19
PMID: 26315761
Edaravone leads to proteome changes indicative of neuronal cell protection in response to oxidative stress.
Neurochem Int 2015 Nov;90():134-41. Epub 2015 jul 29
PMID: 26232623
Parkinson's disease and age: The obvious but largely unexplored link.
Exp Gerontol 2015 Aug;68():33-8. Epub 2014 sep 26
PMID: 25261764
New insight into neurodegeneration: the role of proteomics.
Mol Neurobiol 2014 Jun;49(3):1181-99. Epub 2013 des 10
PMID: 24323427
Structure of Cu(I)-Bound DJ-1 Reveals a Biscysteinate Metal Binding Site at the Homodimer Interface: Insights into Mutational Inactivation of DJ-1 in Parkinsonism.
J Am Chem Soc 2013 Oct 21. Epub 2013 okt 21
PMID: 24144264
Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity.
J Biol Chem 2013 Aug 2;288(31):22809-20. Epub 2013 jun 21
PMID: 23792957
Iron binding to alpha-synuclein affects sub-neuronal species formation
2015, in preparation
A multivariate approach to understand the molecular mechanisms of Parkinson's disease
- Disputert:
- desember 2015
- Hovedveileder:
- Simon Moller
- Mohammed Jami Postdoktor
- Ramavati Pal Postdoktor
- Fatima Bensebaur Ph.d.-kandidat
- Ketan Patil Ph.d.-kandidat
- Indranil Basak Ph.d.-kandidat
- Rashed Abdullah Ph.d.-kandidat
- Guido Alves Prosjektdeltaker
- Jan Petter Larsen Prosjektdeltaker
- Xiang Ming Xu Postdoktor
- Simon Geir Møller Prosjektleder
- Benny Bjørkblom Postdoktor
- Jodi Grødem Postdoktor
- Camilla Hoel Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Faglig rapportering, Helse Vest