Stroma-induced drug resistance in brain tumors
A co-culture model with brain tumor-specific bioluminescence demonstrates astrocytes-induced drug resistance in glioblastoma.
J Transl Med 2014 Oct 4;12(1):278. Epub 2014 okt 4
PMID: 25280402 - Inngår i doktorgradsavhandlingen
Tumor-associated glial cells promote the growth of GBM-xenografts
The transcription factor POU3f2 is expressed in gliomas at levels increasing with malignancy grade, and promotes tumor growth