Gut microbiota in intestinal and systemic inflammatory conditions
- Prosjektnummer
- 911802
- Ansvarlig person
- Tom Hemming Karlsen
- Institusjon
- Helse Bergen HF
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Oral and Gastrointestinal
- Forskningsaktivitet
- 2. Aetiology
Intestinal microbiota in primary sclerosing cholangitis.
Curr Opin Gastroenterol 2017 Mar;33(2):85-92.
PMID: 28030369
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.
Nat Genet 2017 Feb;49(2):269-273. Epub 2016 des 19
PMID: 27992413
Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota.
Nat Genet 2016 Nov;48(11):1396-1406. Epub 2016 okt 10
PMID: 27723756
The gut microbiota contributes to a mouse model of spontaneous bile duct inflammation.
J Hepatol 2017 Feb;66(2):382-389. Epub 2016 okt 5
PMID: 27720803
Microbiota-Dependent Marker TMAO is Not Associated With Decreased Myocardial Perfusion in Well-Treated HIV-Infected Patients as Assessed by 82Rubidium PET/CT.
J Acquir Immune Defic Syndr 2016 Aug 01;72(4):e83-5.
PMID: 27152465
Primary sclerosing cholangitis: 50 years of a gut-liver relationship and still no love?
Gut 2016 Oct;65(10):1579-81. Epub 2016 jul 11
PMID: 27402486
Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation.
Mucosal Immunol 2016 Nov;9(6):1455-1465. Epub 2016 mar 16
PMID: 26982597
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
Nat Genet 2016 May;48(5):510-8. Epub 2016 mar 14
PMID: 26974007
The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls.
Gut 2017 Apr;66(4):611-619. Epub 2016 feb 17
PMID: 26887816
The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis.
Atherosclerosis 2016 Apr;247():64-9. Epub 2016 feb 5
PMID: 26868510
Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery.
Metab Syndr Relat Disord 2016 May;14(4):197-201. Epub 2016 jan 26
PMID: 27081744
Reduced Levels of D-dimer and Changes in Gut Microbiota Composition After Probiotic Intervention in HIV-Infected Individuals on Stable ART.
J Acquir Immune Defic Syndr 2015 Dec 1;70(4):329-37.
PMID: 26258571
Gut microbiota diversity predicts immune status in HIV-1 infection.
AIDS 2015 Nov 28;29(18):2409-18.
PMID: 26355675
Characterization of Intestinal Microbiota in Ulcerative Colitis Patients with and without Primary Sclerosing Cholangitis.
J Crohns Colitis 2015 Nov 2. Epub 2015 nov 2
PMID: 26526357
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study.
Lancet 2015 Oct 18. Epub 2015 okt 18
PMID: 26490195
The Influence of the Autoimmunity-Associated Ancestral HLA Haplotype AH8.1 on the Human Gut Microbiota: A Cross-Sectional Study.
PLoS One 2015;10(7):e0133804. Epub 2015 jul 24
PMID: 26207384
Personalised medicine targeting the gut microbiota?
Tidsskr Nor Laegeforen 2015 Apr 21;135(7):624. Epub 2015 apr 21
PMID: 25899345
Association Between HLA Haplotypes and Increased Serum Levels of IgG4 in Patients With Primary Sclerosing Cholangitis.
Gastroenterology 2015 May;148(5):924-927.e2. Epub 2015 feb 2
PMID: 25655558
High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis.
Nat Genet 2015 Feb;47(2):172-9. Epub 2015 jan 5
PMID: 25559196
Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure.
J Intern Med 2015 Jun;277(6):717-26. Epub 2014 des 1
PMID: 25382824
Genetics in PSC: what do the "risk genes" teach us?
Clin Rev Allergy Immunol 2015 Jun;48(2-3):154-64.
PMID: 24736995
The genetics of complex cholestatic disorders.
Gastroenterology 2013 Jun;144(7):1357-74. Epub 2013 apr 10
PMID: 23583734
Update on primary sclerosing cholangitis.
J Hepatol 2013 Sep;59(3):571-82. Epub 2013 apr 18
PMID: 23603668
Primary sclerosing cholangitis.
Lancet 2013 Nov 9;382(9904):1587-99. Epub 2013 jun 28
PMID: 23810223
Novel insights into autoimmune liver diseases provided by genome-wide association studies.
J Autoimmun 2013 Oct;46():41-54. Epub 2013 aug 7
PMID: 23931959
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.
Nat Genet 2013 Jun;45(6):670-5. Epub 2013 apr 21
PMID: 23603763
Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies.
Gastroenterology 2013 Aug;145(2):339-47. Epub 2013 apr 25
PMID: 23624108
Elevated trimethylamine-N-Oxide (TMAO) is associated with poor prognosis in primary sclerosing cholangitis patients
United Europeean Gastroeneterology J, 2016
Primary sclerosing cholangitis and the gut microbiota - a study on mice, man and microbes
- Disputert:
- oktober 2016
- Hovedveileder:
- Johannes Espolin Roksund Hov
- Rune Rose Tronstad Prosjektdeltaker
- Torunn Fiskerstrand Prosjektdeltaker
- Pål Aukrust Prosjektdeltaker
- Oddrun Anita Gudbrandsen Prosjektdeltaker
- Jan Gunnar Hatlebakk Prosjektdeltaker
- Trygve Hausken Prosjektdeltaker
- Rolf Kristian Berge Prosjektdeltaker
- Marius Trøseid Prosjektdeltaker
- Martin Kummen Ph.d.-kandidat
- Johannes Espolin Roksund Hov Postdoktor
- Tom Hemming Karlsen Prosjektleder
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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