Role of integrins in fibrosis: establishment of a new transgenic mouse model
- Prosjektnummer
- 911899
- Ansvarlig person
- Donald Gullberg
- Institusjon
- Helse Bergen HF
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Skin
- Forskningsaktivitet
- 1. Underpinning
The integrin-collagen connection--a glue for tissue repair?
J Cell Sci 2016 Feb 15;129(4):653-64. Epub 2016 feb 8
PMID: 26857815
The a11 integrin mediates fibroblast-extracellular matrix-cardiomyocyte interactions in health and disease.
Am J Physiol Heart Circ Physiol 2016 Jul 01;311(1):H96-H106. Epub 2016 mai 13
PMID: 27199132
Integrin a11 is overexpressed by tumour stroma of head and neck squamous cell carcinoma and correlates positively with alpha smooth muscle actin expression.
J Oral Pathol Med 2016 Oct 04. Epub 2016 okt 4
PMID: 27699902
Reduced granulation tissue and wound strength in the absence of a11ß1 integrin.
J Invest Dermatol 2015 May;135(5):1435-44. Epub 2015 jan 29
PMID: 25634355
Molecular composition and function of integrin-based collagen glues-introducing COLINBRIs.
Biochim Biophys Acta 2014 Aug;1840(8):2533-48. Epub 2013 des 20
PMID: 24361615
Collagen XXII binds to collagen-binding integrins via the novel motifs GLQGER and GFKGER.
Biochem J 2014 Apr 1;459(1):217-27.
PMID: 24428702
Release of tensile strain on engineered human tendon tissue disturbs cell adhesions, changes matrix architecture, and induces an inflammatory phenotype.
PLoS One 2014;9(1):e86078. Epub 2014 jan 21
PMID: 24465881
Glycated collagen induces a11 integrin expression through TGF-ß2 and Smad3.
J Cell Physiol 2014 Jun 24. Epub 2014 jun 24
PMID: 24962729
Integrin a11ß1: a major collagen receptor on fibroblastic cells.
Adv Exp Med Biol 2014;819():73-83.
PMID: 25023168
Fibroblast a11ß1 integrin regulates tensional homeostasis in fibroblast/A549 carcinoma heterospheroids.
PLoS One 2014;9(7):e103173. Epub 2014 jul 30
PMID: 25076207
Post-translational modifications of integrin ligands as pathogenic mechanisms in disease.
Matrix Biol 2014 Nov;40C():5-9. Epub 2014 aug 10
PMID: 25116951
- Mona Grønning Prosjektdeltaker
- Ning Lu Prosjektdeltaker
- Elon Donald Gullberg Leder av forskningsgruppe
- Cedric Zeltz Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Faglig rapportering, Helse Vest