Interleukin-6 familien og allogen stamcelletransplantasjon
- Prosjektnummer
- 911946
- Ansvarlig person
- Tor Henrik Anderson Tvedt
- Institusjon
- Helse Bergen HF
- Prosjektkategori
- Doktorgradsstipend
- Helsekategori
- Blood, Cancer, Inflammatory and Immune System
- Forskningsaktivitet
- 2. Aetiology, 4. Detection and Diagnosis
Prosjektet er ingen intervensjonsstudie. Pasientene som inkluderes i studien er enten friske eller pasienter som skal til planlagt autolog eller allogen stamcelletransplantasjon ved OUS eller Haukeland Universitetssykehus. Samtykkeskjema, kontaktinformasjon og informasjon om biobanken er offentlig tilgjengelig på avdelingens hjemmeside. https://helse-bergen.no/avdelinger/medisinsk-avdeling/hematologisk-seksjon/forskningsbank-for-blodsjukdommar
Dasatinib as an investigational drug for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia in adults.
Expert Opin Investig Drugs 2019 May;28(5):411-420. Epub 2019 apr 5
PMID: 30916583 - Inngår i doktorgradsavhandlingen
A pilot study of single nucleotide polymorphisms in the interleukin-6 receptor and their effects on pre- and post-transplant serum mediator level and outcome after allogeneic stem cell transplantation.
Clin Exp Immunol 2018 Jul;193(1):130-141. Epub 2018 apr 1
PMID: 29513361 - Inngår i doktorgradsavhandlingen
Immunological Heterogeneity of Healthy Peripheral Blood Stem Cell Donors-Effects of Granulocyte Colony-Stimulating Factor on Inflammatory Responses.
Int J Mol Sci 2018 Sep 22;19(10). Epub 2018 sep 22
PMID: 30249022 - Inngår i doktorgradsavhandlingen
Clonal Heterogeneity Reflected by PI3K-AKT-mTOR Signaling in Human Acute Myeloid Leukemia Cells and Its Association with Adverse Prognosis.
Cancers (Basel) 2018 Sep 14;10(9). Epub 2018 sep 14
PMID: 30223538
Immunological heterogeneity of healthy peripheral blood stem cell donors - preharvesting donor characteristics, additional heterogeneity induced by granulocyte colony-stimulating factor and possible importance for outcome after allotransplantation.
Expert Rev Hematol 2018 Oct;11(10):757-759. Epub 2018 aug 20
PMID: 30126308
Splenic tyrosine kinase (SYK) inhibitors and their possible use in acute myeloid leukemia.
Expert Opin Investig Drugs 2018 Apr;27(4):377-387. Epub 2018 apr 4
PMID: 29611449
Interleukin-6 in Allogeneic Stem Cell Transplantation: Its Possible Importance for Immunoregulation and As a Therapeutic Target.
Front Immunol 2017;8():667. Epub 2017 jun 8
PMID: 28642760
Bendamustine plus rituximab for chronic cold agglutinin disease: results of a Nordic prospective multicenter trial.
Blood 2017 07 27;130(4):537-541. Epub 2017 mai 22
PMID: 28533306
Patients with acute myeloid leukemia can be subclassified based on the constitutive cytokine release of the leukemic cells; the possible clinical relevance and the importance of cellular iron metabolism.
Expert Opin Ther Targets 2017 Apr;21(4):357-369. Epub 2017 mar 3
PMID: 28281897
Antileukemic effects of midostaurin in acute myeloid leukemia - the possible importance of multikinase inhibition in leukemic as well as nonleukemic stromal cells.
Expert Opin Investig Drugs 2017 Mar;26(3):343-355. Epub 2016 des 28
PMID: 28001095
Pretransplant Levels of CRP and Interleukin-6 Family Cytokines; Effects on Outcome after Allogeneic Stem Cell Transplantation.
Int J Mol Sci 2016 Nov 01;17(11). Epub 2016 nov 1
PMID: 27809289 - Inngår i doktorgradsavhandlingen
Nutrition in Allogeneic Stem Cell Transplantion--Clinical Guidelines and Immunobiological Aspects.
Curr Pharm Biotechnol 2016;17(1):92-104.
PMID: 26420050
How should quality of life assessment be integrated in the evaluation of patients with acute myeloid leukemia?
2016
- Elisabeth Ersvær Medveileder
- Annette Brenner Medveileder
- Øystein Bruserud Hovedveileder
- Tor Henrik Anderson Tvedt Ph.d.-kandidat
- Randi Hovland Prosjektdeltaker
- Roald Lindås Prosjektdeltaker
- Aymen B Ahmed Prosjektdeltaker
- Håkon Reikvam Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til Faglig rapportering, Helse Vest