Ablation of persistent atrial fibrillation by using cryoballoon technique.
Norwegian Study of Persistent Atrial Fibrillation Treatment: Cryoballoon Versus Radiofrequency Catheter Ablation (NO PERS-AF)
This project has been approved by REK on 25th Feb. 2016. , The study protocol has been registrated on www.ClinicalTrials.gov. So far two Norwegian centres (Haukeland University Hospital and St. Olavs Hospital) have participated in this study. 18 patients have been enrolled and followed up.
This project has been registered on the ClinicalTrial.gov website as a two-center, prospective, randomized controlled clinical trial entitled “Norwegian study of persistent atrial fibrillation treatment: cryoballoon versus radiofrequency catheter (NO PERS-AF)”. The aim of this study is to compare the clinical outcome of ablation treatment for atrial fibrillation between cryoballoon and radiofrequency catheter ablation. So far 18 patients (16 from Haukeland University Hospital and 2 from St. Olavs Hospital) have been enrolled in this study. Nine patients underwent cryoablation and the other 9 patients underwent radiofrequency ablation. Pulmonary vein isolation was achieved in all patients. No serious adverse events or complications are reported. All patients are followed up according to study schedule without missing visit. Quality of life and the symptom burden of atrial fibrillation are evaluated. The heart rhythm of patient is recorded by 7-days Holter. We have presented the design of the study at regional and Nordic meetings. No paper has been published by now. We have two abstracts accepted and presented on HRS 2016, and we submit one abstract to EHRA/Cardiostom conference 2017. Names of abstracts are listed below. 1. Collective impacts of power, contact force and ablation time on ablation effect of atrial 2. Ablation index correlates with impedance drop during catheter ablation of atrial fibrillation. 3. Comparison of serum levels of troponin T and C-reactive protein following atrial fibrillation ablation with radiofrequency and cryo-energy.