Human and murine lupus nephritis – molecular biology, genetics and epigenetics
- Prosjektnummer
- SFP1133-13
- Ansvarlig person
- Ole Petter Rekvig
- Institusjon
- UiT Norges arktiske universitet
- Prosjektkategori
- Flerårig forskningsprosjekt
- Helsekategori
- Renal and urogenital
- Forskningsaktivitet
- 2. Aetiology
Future Perspectives on Pathogenesis of Lupus Nephritis: Facts, Problems, and Potential Causal Therapy Modalities.
Am J Pathol 2016 Nov;186(11):2772-2782. Epub 2016 sep 21
PMID: 27664472
Galectin-3 binding protein links circulating microparticles with electron dense glomerular deposits in lupus nephritis.
Lupus 2015 Oct;24(11):1150-60. Epub 2015 apr 2
PMID: 25837289
The anti-DNA antibody: origin and impact, dogmas and controversies.
Nat Rev Rheumatol 2015 Sep;11(9):530-40. Epub 2015 jun 2
PMID: 26034836
TNFa Amplifies DNaseI Expression in Renal Tubular Cells while IL-1ß Promotes Nuclear DNaseI Translocation in an Endonuclease-Inactive Form.
PLoS One 2015;10(6):e0129485. Epub 2015 jun 11
PMID: 26065428
Murine and Human Lupus Nephritis: Pathogenic Mechanisms and Theoretical Strategies for Therapy.
Semin Nephrol 2015 Sep;35(5):427-38.
PMID: 26573545
Anti-dsDNA antibodies as a classification criterion and a diagnostic marker for systemic lupus erythematosus: critical remarks.
Clin Exp Immunol 2015 Jan;179(1):5-10.
PMID: 24533624
Clinical phenotype associations with various types of anti-dsDNA antibodies in patients with recent onset of rheumatic symptoms. Results from a multicentre observational study.
Lupus Sci Med 2014;1(1):e000007. Epub 2014 apr 1
PMID: 25396058
The pathogenesis and diagnosis of systemic lupus erythematosus: still not resolved.
Semin Immunopathol 2014 May;36(3):301-11. Epub 2014 apr 25
PMID: 24763531
Review: antinucleosome antibodies: a critical reflection on their specificities and diagnostic impact.
Arthritis Rheumatol 2014 May;66(5):1061-9.
PMID: 24470458
LMW heparin prevents increased kidney expression of proinflammatory mediators in (NZBxNZW)F1 mice.
Clin Dev Immunol 2013;2013():791262. Epub 2013 sep 17
PMID: 24151519
Lupus nephritis: enigmas, conflicting models and an emerging concept.
Mol Med 2013;19():161-9. Epub 2013 jul 24
PMID: 23752208
Low diagnostic and predictive value of anti-dsDNA antibodies in unselected patients with recent onset of rheumatic symptoms: results from a long-term follow-up Scandinavian multicentre study.
Scand J Rheumatol 2013;42(4):311-6. Epub 2013 mar 16
PMID: 23496224
Impact of the tumor necrosis factor receptor-associated protein 1 (Trap1) on renal DNaseI shutdown and on progression of murine and human lupus nephritis.
Am J Pathol 2013 Mar;182(3):688-700. Epub 2012 des 27
PMID: 23273922
Lupus nephritis: Biological consequences of renal DNaseI gene silencing
- Disputert:
- oktober 2013
- Hovedveileder:
- Ole Petter Rekvig
- Lorena Arranz Prosjektdeltaker
- Kjersti Daae Horvei Prosjektdeltaker
- Hege Lynum Pedersen Prosjektdeltaker
- Dhivya Thiyagarajan Postdoktorstipendiat
- Natalya Seredkina Prosjektdeltaker
- Ole Petter Rekvig Prosjektleder
- Johan van der Vlag Prosjektdeltaker
- Ian Geoffrey Mills Prosjektdeltaker
- Thomas Winkler Prosjektdeltaker
- Henrik Nielsen Prosjektdeltaker
- Gudrun Norby Prosjektdeltaker
- Steinar Johansen Prosjektdeltaker
- Elin Synnøve Mortensen Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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