Linking atherosclerotic plaque calcification and thrombosis: from basic research to clinical study
Increased expression of TF in BMP-7-treated human mononuclear cells depends on activation of select MAPK signaling pathways.
Thromb Res 2011 Dec;128(6):e154-9. Epub 2011 aug 6
Low thrombogenicity of calcified atherosclerotic plaques is associated with bone morphogenetic protein-2-dependent inhibition of tissue factor expression.
Blood Coagul Fibrinolysis 2011 Dec;22(8):642-50.
BMP-2 inhibits TF expression in human monocytes by shutting down MAPK signaling and AP-1 transcriptional activity.
Thromb Res 2012 Apr;129(4):e106-11. Epub 2011 nov 25
Circulating monocytes mirror the imbalance in TF and TFPI expression in carotid atherosclerotic plaques with lipid-rich and calcified morphology.
Thromb Res 2012 Apr;129(4):e134-41. Epub 2011 des 15
Bone morphogenetic protein -7 increases thrombogenicity of lipid-rich atherosclerotic plaques via activation of tissue factor.
Thromb Res 2010 Oct;126(4):306-10. Epub 2010 jul 24
The role of TFPI in regulation of TF-induced thrombogenicity on the surface of human monocytes.
Thromb Res 2010 Nov;126(5):418-25. Epub 2010 aug 17
BMP-7-induced TF expression in human monocytes is associated with increased NF-kB, but not AP-1 transcriptional activity
Thrombosis Research 2011 (Revision pending)