Hypoxia and reoxygenation in newborn piglets and human infants
- Prosjektnummer
- 1-502
- Ansvarlig person
- Ola Didrik Saugstad professor dr.med,
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Forskningsprosjekt
- Helsekategori
- Reproductive Health and Childbirth
- Forskningsaktivitet
- 7. Disease Management
Accumulation of 8-oxoguanine in liver DNA during hyperoxic resuscitation of newborn mice.
Pediatr Res 2009 Nov;66(5):533-8.
PMID: 19668103
Resuscitation of Hypoxic Newborn Piglets with Supplementary Oxygen induces Dose-dependent Increase in Matrix Metalloproteinase-activity and Down-regulates Vital Genes.
Pediatr Res 2009 Dec.
PMID: 20010314
Post-hypoxic hypothermia is protective in human NT2-N neurons regardless of oxygen concentration during reoxygenation.
Brain Res 2009 Mar;1259():80-9. Epub 2008 des 31
PMID: 19146835
Oxygen in health and disease: Regulation of oxygen homeostasis - Clinical implications.
Pediatr Res 2008 Oct. Epub 2008 okt 10
PMID: 18852690
Nicotine in a small-to-moderate dose does not cause a significant increase in plasma catecholamine levels in newborn piglets.
Neonatology 2008;94(4):279-83. Epub 2008 sep 11
PMID: 18784424
Resuscitation with 21 or 100% oxygen in hypoxic nicotine-pretreated newborn piglets: possible neuroprotective effects of nicotine.
Neonatology 2008;93(1):36-44. Epub 2007 jul 12
PMID: 17630496
To oxygenate or not to oxygenate--that is the question.
Am J Physiol Heart Circ Physiol 2008 Oct;295(4):H1371-2. Epub 2008 aug 15
PMID: 18708440
Effects of nicotine infusion on striatal glutamate and cortical non-protein-bound iron in hypoxic newborn piglets.
Neonatology 2008;94(4):284-92. Epub 2008 sep 11
PMID: 18784425
Resuscitation of newborn infants with 21% or 100% oxygen: an updated systematic review and meta-analysis.
Neonatology 2008;94(3):176-82. Epub 2008 jul 9
PMID: 18612215
Resuscitation of hypoxic newborn piglets with oxygen induces a dose-dependent increase in markers of oxidation.
Pediatr Res 2007 Nov;62(5):559-63.
PMID: 18049371
Resuscitation with Oxygen decreases BDNF and increases Caspase-3
Pediatric Academic Societies, Baltimore, May 2009
Resuscitation with pure oxygen vs room-air down regulates VEGFR2 and HIF-1a in newborn piglets retina and may indicate less neur
Pediatric Academic Societies, Baltimore, May 2009
Metabolomic characterization of hypoxia-reoxygenation injury in piglets
ESPNIC, Verona 2009
resuscitation with pure oxygen vs room- down regulates HIF-1a and VEGFa in newborn pigs choroid.
European Society for Paediatric Research, Hamburg, October 2009
New insights into asphyxia and biomarker discovery:
European Society for Paediatric Research, Hamburg, October 2009
Resuscitation of the Newborn
Conn's Current Therapy, Saunders, Philadelphia 2009
DOSE DEPENDANT INCREASE OF HYDROXYL RADICAL FORMATION AND DNA OXIDATION BY NEWBORN RESUSCITATION WITH 40%, 60% OR 100%.
International Workshop of Surfactant Replacement, 7-10 June 2007, Ancona, Italy.
Resuscitation with 100% Oxygen Alters Metalloproteinase (MMP) Gelatinase Activity in Newborn Piglets Liver.
European Society of Paediatric Research Annual Meeting, Prague Oct 6-8 2007:
High Oxygen Concentration by Resuscitation Alters Gene Expression
Poster: Pediatric Academic Societies Annual meeting, Toronto May 3-8, 2007
High Oxygen Concentration by Resuscitation Alters Gene Expression
Poster: Pediatric Academic Societies Annual meeting, Toronto May 3-8, 2007
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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