Transplantat av amnionhinne dekket med hornhinneepitel ved korneaskade - en studie av dyrkningsbetingelser
- Prosjektnummer
- 2006260
- Ansvarlig person
- Torstein Lyberg
- Institusjon
- Oslo universitetssykehus HF - Ullevål sykehus
- Prosjektkategori
- Fagspes. kjernekomp.miljø
- Helsekategori
- Eye
- Forskningsaktivitet
- 5. Treatment Developement
The impact of de-epithelialization of the amniotic membrane matrix on morphology of cultured human limbal epithelial cells subject to eye bank storage.
Cornea 2010 Apr;29(4):439-45.
PMID: 20164752
Comparison of the histology, gene expression profile, and phenotype of cultured human limbal epithelial cells from different limbal regions.
Invest Ophthalmol Vis Sci 2009 Nov;50(11):5165-72. Epub 2009 jul 2
PMID: 19578011
Sterility control and long-term eye-bank storage of cultured human limbal epithelial cells for transplantation.
Br J Ophthalmol 2009 Jul;93(7):980-3. Epub 2009 feb 11
PMID: 19211610
A novel method for preserving cultured limbal epithelial cells.
Br J Ophthalmol 2007 Jun;91(6):797-800. Epub 2006 nov 23
PMID: 17124242
Effect of limbal explant orientation on the histology, phenotype, ultrastructure and barrier function of cultured limbal epithelial cells.
Acta Ophthalmol Scand 2007 Jun;85(4):377-86. Epub 2007 jan 31
PMID: 17263847
Effects of organ culture and Optisol-GS storage on structural integrity, phenotypes, and apoptosis in cultured corneal epithelium.
Invest Ophthalmol Vis Sci 2007 Dec;48(12):5484-93.
PMID: 18055796
Storage of cultured limbal epithelial cells in various media and temperatures
The 2nd Asia Cornea Society Biennial Scientific Meeting, Kyoto, Japan
Novel technology in regenerative medicine - storage and transportation of cultured epithelial cells
The Norwegian Stem Cell Meeting, Losby, Lørenskog, Norway
The amniotic membrane - preparation, storage and transportation.
The Norwegian Society of Ophthalmologists, Soria Moria, Norway
Norske leger står foran et stort medisinsk gjennombrudd
NRK - Schrödingers katt
Effect of Biopsy Location and Size on Phenotype and Proliferative Ability of Cultured Rat Conjunctival Tissue.
Ophthalmol. Vis. Sci. 2010 E-abstract 1912
Treating limbal stem cell deficiency using different sources of cultured cells
DUO-publication (6 months medical student project).
Corneal storage
DUO-publication (3 months medical student project).
Effects of the size of explants on epithelial thickness, number of cell layers, ultrastructure, and phenotype of cultured cells
European Eye Bank Association, Annual Meeting, Amsterdam, The Netherlands, 2009
Storage of Cultured Human Limbal Epithelial Cells in Optisol-GS at 23°C versus 5°C
Invest. Ophthalmol. Vis. Sci. 2009 E-abstract 1778
Genome-Wide Transcriptional Analysis of Cultured Human Limbal Epithelial Cells Following Hypothermic Storage in Optisol-GS
Invest. Ophthalmol. Vis. Sci. 2009 E-abstract 1773
Transplant Storage
Patent application filed on October 30, 2008 by Schepens Eye Research Institute, Harvard Medical School, Boston, MA and Oslo universtity hospital, Norway
Eye bank storage of cultured human limbal epithelial cells: sterility control and long-term preservation
British Journal of Ophthalology, in press
Comparison of histology, gene expression, and phenotype of cultured limbal epithelial
Investigative Ophthalmology and visual science, accepted for revision
Sterility Testing of Storage Media, Long-Term Preservation, and Deepithelialization of the Amniotic Membrane Substrate Invest.
Invest. Ophthalmol. Vis. Sci. 2008 47: E-Abstract 5717.
Identification of Predilection Target Sites for Tissue Harvesting in Corneal Epithelial Tissue Engineering Ophthalmol.
Vis. Sci. 2008 47: E-Abstract 5746.
Effects of the size of explants on adhesion and outgrowth of ex vivo expanded limbal epithelial cells,
XXXVIII Nordic Congress of Ophtalmology, Tromsoe, Norway, 2008.
The rationale of transplantation of preserved cultured limbal epithelial cells: Possibilities and limitations
XXXVIII Nordic Congress of Ophtalmology, Tromsoe, Norway, 2008.
Effects of the size of explants on epithelial thickness, number of cell layers, ultrastructure, and phenotype of cultured limbal
European Eye Bank Association, Annual Meeting, Amsterdam, The Netherlands, 2009
Gene profiling of OptisolGS storage of Cultured Limbal Epithelial Cells at 5 ºC.
Invest. Ophthalmol. Vis. Sci. (submitted).
Novel Technology in Regenerative Medicine - Eye Bank Storage of Cultured Limbal Explant Cultures for Transplantation
- Disputert:
- mai 2010
- Hovedveileder:
- Torstein Lyberg
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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