Establishment of a dendritic cell vaccine targeting tumor stem cells in patients with glioblastoma
- Prosjektnummer
- 2009024
- Ansvarlig person
- Iver Arne Langmoen
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Nytt flerårig forskningsprosjekt
- Helsekategori
- Neurological
- Forskningsaktivitet
- 5. Treatment Developement
Comparison of glioma stem cells to neural stem cells from the adult human brain identifies dysregulated Wnt- signaling and a fingerprint associated with clinical outcome.
Exp Cell Res 2013 Aug 15;319(14):2230-43. Epub 2013 jun 18
PMID: 23791939
Inhibition of tumor formation and redirected differentiation of glioblastoma cells in a xenotypic embryonic environment.
Dev Dyn 2013 Sep;242(9):1078-93. Epub 2013 jul 29
PMID: 23780720
Expansion of multipotent stem cells from the adult human brain.
PLoS One 2013;8(8):e71334. Epub 2013 aug 14
PMID: 23967194
Recruited brain tumor-derived mesenchymal stem cells contribute to brain tumor progression.
Stem Cells 2014 May;32(5):1110-23.
PMID: 24302539
Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma.
Cancer Immunol Immunother 2013 Sep;62(9):1499-509. Epub 2013 jul 2
PMID: 23817721
EGF signalling and rapamycin-mediated mTOR inhibition in glioblastoma multiforme evaluated by phospho-specific flow cytometry.
J Neurooncol 2013 Mar;112(1):49-57. Epub 2013 jan 9
PMID: 23299461
A comparative study of the structural organization of spheres derived from the adult human subventricular zone and glioblastoma biopsies.
Exp Cell Res 2011 Apr;317(7):1049-59. Epub 2011 jan 1
PMID: 21199649
Brain tumor stem cells maintain overall phenotype and tumorigenicity after in vitro culturing in serum-free conditions.
Neuro Oncol 2010 Dec;12(12):1220-30. Epub 2010 sep 14
PMID: 20843775
Characterization of stem cell-enriched glioblastoma cells in vitro and in xenotypic tissue environment
- Disputert:
- desember 2013
- Hovedveileder:
- Joel Glover
Propagation and characterization of stem like cells from brain tumors...
- Disputert:
- juni 2011
- Hovedveileder:
- Iver A Langmoen
- Gustav Gaudernack Prosjektdeltaker
- Mrinal Joel Doktorgradsstipendiat
- Cecilie Sandberg Doktorgradsstipendiat
- Steinar Aamdal Prosjektdeltaker
- Gunnar Kvalheim Prosjektdeltaker
- Einar O. Vik-Mo Doktorgradsstipendiat
- Iver Arne Langmoen Prosjektleder
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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