Meningococcal infection – disease mechanisms of lethal shock
- Prosjektnummer
- 2009062
- Ansvarlig person
- Petter Brandtzæg
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Doktorgradsstipend
- Helsekategori
- Infection
- Forskningsaktivitet
- 2. Aetiology
Neisseria meningitidis and Escherichia coli are protected from leukocyte phagocytosis by binding to erythrocyte complement receptor 1 in human blood.
Mol Immunol 2011 Sep;48(15-16):2159-69. Epub 2011 aug 11
PMID: 21839519 - Inngår i doktorgradsavhandlingen
The role of bradykinin and the effect of the bradykinin receptor antagonist icatibant in porcine sepsis.
Shock 2011 Nov;36(5):517-23.
PMID: 21921836
CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli sepsis in pigs.
FASEB J 2010 Mar;24(3):712-22. Epub 2009 okt 19
PMID: 19841036
Critical roles of complement and antibodies in host defense mechanisms against Neisseria meningitidis as revealed by human complement genetic deficiencies.
Infect Immun 2010 Feb;78(2):802-9. Epub 2009 nov 23
PMID: 19933829
Dissecting the effects of lipopolysaccharides from nonlipopolysaccharide molecules in experimental porcine meningococcal sepsis.
Crit Care Med 2010 Jun;38(6):1467-74.
PMID: 20400898
A new dynamic porcine model of meningococcal shock.
Shock 2009 Sep;32(3):302-9.
PMID: 19174740
Human genetic deficiencies reveal the roles of complement in the inflammatory network: lessons from nature.
Proc Natl Acad Sci U S A 2009 Sep;106(37):15861-6. Epub 2009 aug 26
PMID: 19717455
Meningococcal infections
Warrell DA, Cox TM, Firth JD (eds) Oxford Textbook of Medicine, 5th Ed. Oxford Press, Oxford 2010: p209-722
Cand med
- Disputert:
- juni 2011
- Hovedveileder:
- Petter Brandtzæg
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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