Gene-level consequences of new cancer-specific chromosomal rearrangements
- Prosjektnummer
- 2009077
- Ansvarlig person
- Sverre Heim
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Doktorgradsstipend
- Helsekategori
- Cancer
- Forskningsaktivitet
- 4. Detection and Diagnosis
MEAF6/PHF1 is a recurrent gene fusion in endometrial stromal sarcoma.
Cancer Lett 2014 May 28;347(1):75-8. Epub 2014 feb 11
PMID: 24530230
Low frequency of ESRRA-C11orf20 fusion gene in ovarian carcinomas.
PLoS Biol 2014 Feb;12(2):e1001784. Epub 2014 feb 4
PMID: 24504521
Sequential combination of karyotyping and RNA-sequencing in the search for cancer-specific fusion genes.
Int J Biochem Cell Biol 2014 Aug;53():462-5. Epub 2014 mai 23
PMID: 24863361
Fusion of ZMYND8 and RELA genes in acute erythroid leukemia.
PLoS One 2013;8(5):e63663. Epub 2013 mai 7
PMID: 23667654
RNA sequencing identifies fusion of the EWSR1 and YY1 genes in mesothelioma with t(14;22)(q32;q12).
Genes Chromosomes Cancer 2013 Aug;52(8):733-40. Epub 2013 apr 30
PMID: 23630070
Fusion of the ZC3H7B and BCOR genes in endometrial stromal sarcomas carrying an X;22-translocation.
Genes Chromosomes Cancer 2013 Jul;52(7):610-8. Epub 2013 apr 12
PMID: 23580382
High-throughput sequencing identifies an NFIA/CBFA2T3 fusion gene in acute erythroid leukemia with t(1;16)(p31;q24).
Leukemia 2013 Apr;27(4):980-2. Epub 2012 sep 11
PMID: 23032695 - Inngår i doktorgradsavhandlingen
Cryptic FUS-ERG fusion identified by RNA-sequencing in childhood acute myeloid leukemia.
Oncol Rep 2013 Dec;30(6):2587-92. Epub 2013 sep 25
PMID: 24068373
Myeloid leukemia with t(7;21)(p22;q22) and 5q deletion.
Oncol Rep 2013 Oct;30(4):1549-52. Epub 2013 jul 18
PMID: 23877199
Whole-transcriptome sequencing identifies novel IRF2BP2-CDX1 fusion gene brought about by translocation t(1;5)(q42;q32) in mesenchymal chondrosarcoma.
PLoS One 2012;7(11):e49705. Epub 2012 nov 21
PMID: 23185413 - Inngår i doktorgradsavhandlingen
A novel TCF3-HLF fusion transcript in acute lymphoblastic leukemia with a t(17;19)(q22;p13).
Cancer Genet 2012 Dec;205(12):669-72. Epub 2012 nov 20
PMID: 23181981
Myelodysplastic syndrome with a t(2;11)(p21;q23-24) and translocation breakpoint close to miR-125b-1.
Cancer Genet 2012 Oct;205(10):528-32. Epub 2012 sep 1
PMID: 22944560
Novel fusion of MYST/Esa1-associated factor 6 and PHF1 in endometrial stromal sarcoma.
PLoS One 2012;7(6):e39354. Epub 2012 jun 22
PMID: 22761769
t(12;13)(q14;q31) leading to HMGA2 upregulation in acute myeloid leukaemia.
Br J Haematol 2012 Jun;157(6):769-71. Epub 2012 mar 7
PMID: 22404713 - Inngår i doktorgradsavhandlingen
Similar cytogenetic findings in two synchronous secondary peripheral chondrosarcomas in a patient with multiple osteochondromas.
Cancer Genet 2011 Dec;204(12):677-81.
PMID: 22285020
Identification of chromosomal breakpoints of cancer-specific translocations by rolling circle amplification and long-distance inverse PCR.
Cancer Genet 2011 Aug;204(8):458-61.
PMID: 21962896
Paratesticular leiomyoma with a der(14)t(12;14)(q15;q24).
Cancer Genet 2011 Aug;204(8):465-8.
PMID: 21962898
Translocation t(1;16)(p31;q24) rearranging CBFA2T3 is specific for acute erythroid leukemia.
Leukemia 2011 Sep;25(9):1510-2. Epub 2011 mai 24
PMID: 21606959
Identification of the TAF15-ZNF384 fusion gene in two new cases of acute lymphoblastic leukemia with a t(12;17)(p13;q12).
Cancer Genet 2011 Mar;204(3):147-52.
PMID: 21504714 - Inngår i doktorgradsavhandlingen
Expression pattern of the septin gene family in acute myeloid leukemias with and without MLL-SEPT fusion genes.
Leuk Res 2010 May;34(5):615-21. Epub 2009 sep 12
PMID: 19748670
Array-CGH analysis of microdissected chromosome 19 markers in ovarian carcinoma identifies candidate target genes.
Genes Chromosomes Cancer 2010 Nov;49(11):1046-53.
PMID: 20725991
Genotypic and phenotypic classification of cancer: How should the impact of the two diagnostic approaches best be balanced?
Genes Chromosomes Cancer 2010 Sep;49(9):763-74.
PMID: 20607708
Genomic aberrations in borderline ovarian tumors.
J Transl Med 2010;8():21. Epub 2010 feb 26
PMID: 20184781
Tumor spreading to the contralateral ovary in bilateral ovarian carcinoma is a late event in clonal evolution.
J Oncol 2010;2010():646340. Epub 2009 sep 15
PMID: 19759843
t(19;22)(q13;q12) Translocation leading to the novel fusion gene EWSR1-ZNF444 in soft tissue myoepithelial carcinoma.
Genes Chromosomes Cancer 2009 Dec;48(12):1051-6.
PMID: 19760602
Genomic aberrations in 80 cases of primary glioblastoma multiforme: Pathogenetic heterogeneity and putative cytogenetic pathways.
Genes Chromosomes Cancer 2009 Oct;48(10):908-24.
PMID: 19603525
Clinical and cytogenetic features of a population-based consecutive series of 285 pediatric T-cell acute lymphoblastic leukemias: rare T-cell receptor gene rearrangements are associated with poor outcome.
Genes Chromosomes Cancer 2009 Sep;48(9):795-805.
PMID: 19530250
Cytogenetic analysis of 101 giant cell tumors of bone: nonrandom patterns of telomeric associations and other structural aberrations.
Genes Chromosomes Cancer 2009 Jul;48(7):583-602.
PMID: 19396867
t(3;21)(q22;q22) leading to truncation of the RYK gene in atypical chronic myeloid leukemia.
Cancer Lett 2009 May;277(2):205-11. Epub 2009 jan 24
PMID: 19168282
A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis.
Mol Cancer 2009;8():5. Epub 2009 jan 19
PMID: 19152679
Reverse painting of microdissected chromosome 19 markers in ovarian carcinoma identifies a complex rearrangement map.
Genes Chromosomes Cancer 2009 Feb;48(2):184-93.
PMID: 18973136
Identification of the TAF15/ZNF384 fusion gene in two
Cancer Genetics. In press.
Translocation t(1;16)(p31;q24) rearranging CBFA2T3 is specific f
Leukemia. In press.
Cancer Cytogenetics, 3rd Edition.
Cancer Cytogenetics, 3rd Edition, 2009, Wiley-Blackwell, New Jersey. 736 pp.
A new approach to an old problem.
In: Heim S, Mitelman F (Eds). Cancer Cytogenetics, 3rd Edition, 2009, Wiley-Blackwell, New Jersey, pp 1-7.
Cytogenetic nomenclature.
In: Heim S, Mitelman F (Eds). Cancer Cytogenetics, 3rd Edition, 2009, Wiley-Blackwell, New Jersey, pp17-23.
Nonrandom chromosome abnormalities in cancer – an overview.
In: Heim S, Mitelman F (Eds). Cancer Cytogenetics, 3rd Edition,2009, Wiley-Blackwell, New Jersey, pp 25-43.
Tumors of the digestive tract.
In: Heim S, Mitelman F (Eds). Cancer Cytogenetics, 3rd Edition,2009, Wiley-Blackwell, New Jersey, pp 429-461.
Tumors of the breast.
In: Heim S, Mitelman F (Eds). Cancer Cytogenetics, 3rd Edition, 2009, Wiley-Blackwell, New Jersey, pp 403-518.
Tumors of the female genital organs.
In: Heim S, Mitelman F (Eds). Cancer Cytogenetics, 3rd Edition,2009, Wiley-Blackwell, New Jersey, pp 519-556.
Tumors of the male genital organs.
In: Heim S, Mitelman F (Eds). Cancer Cytogenetics, 3rd Edition, 2009, Wiley-Blackwell, New Jersey, pp 557-575.
Tumors of the skin.
In: Heim S, Mitelman F (Eds). Cancer Cytogenetics, 3rd Edition. 2009, Wiley-Blackwell, New Jersey, pp 641-653.
Gene-level consequences of new cancer-specific chromosomal rearrangements
- Disputert:
- mai 2014
- Hovedveileder:
- Francesca Micci
- Kaja Beate Nyquist Doktorgradsstipendiat
- Sverre Heim Biveileder
- Ioannis Panagopoulos Forsker (annen finansiering)
- Francesca Micci Biveileder
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til eRapport