Genetic polymorphism in genes coding for estradiol regulation and metabolism with impact on mammographic density and breast cancer
- Prosjektnummer
- 2010022
- Ansvarlig person
- Vessela N. Kristensen
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Doktorgradsstipend
- Helsekategori
- Cancer
- Forskningsaktivitet
- 3. Prevention
Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling.
Proc Natl Acad Sci U S A 2012 Feb;109(8):2802-7. Epub 2011 sep 9
PMID: 21908711
Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features.
BMC Med Genomics 2011;4():77. Epub 2011 nov 1
PMID: 22044755
Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas.
BMC Cancer 2011;11():332. Epub 2011 aug 3
PMID: 21812955
Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression.
Mol Oncol 2010 Apr;4(2):98-118. Epub 2009 des 11
PMID: 20060370
NOTCH2 in breast cancer: association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations.
Mol Cancer 2010;9():113. Epub 2010 mai 19
PMID: 20482849
Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer.
Breast Cancer Res 2010;12(1):R3. Epub 2010 jan 7
PMID: 20056007
Expression levels of uridine 5'-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density.
Breast Cancer Res 2010;12(4):R65. Epub 2010 aug 27
PMID: 20799965 - Inngår i doktorgradsavhandlingen
Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma metabolic levels and mammographic density.
BMC Med Genomics 2010;3():9. Epub 2010 mar 19
PMID: 20302654 - Inngår i doktorgradsavhandlingen
Candidate SNP analysis integrated with mRNA expression and hormone levels reveal influence on mammographic density and breast ca
under review in BMC Med Genomics
Mutations for the people
EMBO J MM
Common genetic variation and mammographic density: risk factors for breast cancer.
- Disputert:
- juni 2012
- Hovedveileder:
- Vessela Kristensen
MSc, PhD
- Disputert:
- juni 2010
- Hovedveileder:
- Vessela Kristensen
MD
- Disputert:
- desember 2010
- Hovedveileder:
- Åslaug Helland
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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