Translational research to identify the induction mechanism of T cell lymphomas in mice and man
- Prosjektnummer
- 2010033
- Ansvarlig person
- Ludvig A Munthe
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Postdoktorstipend
- Helsekategori
- Blood, Cancer, Inflammatory and Immune System
- Forskningsaktivitet
- 2. Aetiology
Chronic lymphocytic leukemia cells express CD38 in response to Th1 cell-derived IFN-? by a T-bet-dependent mechanism.
J Immunol 2015 Jan 15;194(2):827-35. Epub 2014 des 10
PMID: 25505279
Targeted DNA vaccines eliciting crossreactive anti-idiotypic antibody responses against human B cell malignancies in mice.
J Transl Med 2014;12():207. Epub 2014 jul 25
PMID: 25059102
How Do CD4(+) T Cells Detect and Eliminate Tumor Cells That Either Lack or Express MHC Class II Molecules?
Front Immunol 2014;5():174. Epub 2014 apr 15
PMID: 24782871
Association of variable number of tandem repeats in the coding region of the FAM46A gene, FAM46A rs11040 SNP and BAG6 rs3117582 SNP with susceptibility to tuberculosis.
PLoS One 2014;9(3):e91385. Epub 2014 mar 13
PMID: 24625963
Idiotype-specific Th cells support oligoclonal expansion of anti-dsDNA B cells in mice with lupus.
J Immunol 2014 Sep 15;193(6):2691-8. Epub 2014 aug 15
PMID: 25127856
Naive idiotope-specific B and T cells collaborate efficiently in the absence of dendritic cells.
J Immunol 2014 May 1;192(9):4174-83. Epub 2014 apr 4
PMID: 24706724
Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells.
Cell Rep 2013 Aug 15;4(3):566-77. Epub 2013 aug 8
PMID: 23933259
Immune-regulatory mechanisms in systemic autoimmune and rheumatic diseases.
Clin Dev Immunol 2012;2012():957151. Epub 2012 mar 7
PMID: 22474487
NF-?B activity in perinatal brain during infectious and hypoxic-ischemic insults revealed by a reporter mouse.
Brain Pathol 2012 Jul;22(4):499-510. Epub 2011 des 12
PMID: 22059637
B-cells and their targeting in rheumatoid arthritis--current concepts and future perspectives.
Autoimmun Rev 2011 Nov;11(1):28-34. Epub 2011 jul 14
PMID: 21777703
Syk kinase inhibitors reduce CD40L-induced proliferation of chronic lymphocytic leukemia cells but not normal B cells.
Haematologica. 2016 Feb;101(2):e59-62. doi: 10.3324/haematol.2015.135590. Epub 2015 Nov 20
Chronic Lymphocytic Leukemia Cells Express CD38 in Response to Th1 Cell-Derived IFN-? by a T-bet-Dependent Mechanism
Epub 2014 Dec 10: J Immunol. 2015 Jan 15;194(2):827-35. doi: 10.4049/jimmunol.1401350.
What makes the B cell lymphomas grow?
Global Academic Programs - (GAP). MD Anderson Cancer Center. Oslo, May 2012. Lecture.
Leukemic B Cells Can Collaborate with Antigen-specific T Helper Cells and Receive Help to Proliferate
12th Annual Meeting of the Federation of Clinical Immunology Societies (FOCIS 2012), in Vancouver, Canada, June 2012, poster presentation
Leukemic B Cells Can Collaborate with Antigen-specific T Helper Cells and Receive Help to Proliferate
FOCIS 2012 Trainee Satellite Symposium, in Vancouver, Canada, June 2012, oral presentation
T cells in CLL
UK-CLL forum, London March 2012. Invited lecture.
Leukemic B cells receive help from autologous T helper cells through a mechanism involving recognition of endogenous antigen
World Immune Regulation Meeting V, Davos, Switzerland, March 2012, poster presentation
- Dong Wang Postdoktorstipendiat
- Ludvig Andre Munthe Prosjektleder
- Geir Erland Tjønnfjord Prosjektdeltaker
- Yngvar Fløisand Prosjektdeltaker
- Peter Szodoray Forsker (annen finansiering)
- Anna Maria Parente Ribes Doktorgradsstipendiat
- Wang Dong Forsker (annen finansiering)
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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