Functional studies of gene products involved in cancer progression and metastasis – possibilities for therapeutic intervention
- Prosjektnummer
- 2010061
- Ansvarlig person
- Gunhild Mari Mælandsmo
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Doktorgradsstipend
- Helsekategori
- Cancer
- Forskningsaktivitet
- 1. Underpinning
Metastasis-associated protein S100A4 induces a network of inflammatory cytokines that activate stromal cells to acquire pro-tumorigenic properties.
Cancer Lett 2014 Mar 1;344(1):28-39. Epub 2013 nov 8
PMID: 24215866 - Inngår i doktorgradsavhandlingen
EMMPRIN is associated with S100A4 and predicts patient outcome in colorectal cancer.
Br J Cancer 2012 Aug;107(4):667-74. Epub 2012 jul 10
PMID: 22782346
Expression of S100A4, ephrin-A1 and osteopontin in non-small cell lung cancer.
BMC Cancer 2012;12():333. Epub 2012 aug 1
PMID: 22853000
The metastasis-promoting protein S100A4 regulates mammary branching morphogenesis.
Dev Biol 2011 Apr;352(2):181-90. Epub 2010 des 31
PMID: 21195708
Osteopontin--an important downstream effector of S100A4-mediated invasion and metastasis.
Int J Cancer 2011 Aug;129(4):780-90. Epub 2011 mar 11
PMID: 20957651
Nuclear S100A4 is a novel prognostic marker in colorectal cancer.
Eur J Cancer 2010 Nov;46(16):2919-25. Epub 2010 aug 16
PMID: 20719498
Comment on the Importance of S100A4 in regulation of MMP-13.
J Biol Chem 2010 Dec;285(53):le23; author reply le24.
PMID: 21186294
S100A4 and metastasis: a small actor playing many roles.
Am J Pathol 2010 Feb;176(2):528-35. Epub 2009 des 17
PMID: 20019188
Evaluation of potential interactions between the metastasis-associated protein S100A4 and the tumor suppressor protein p53.
Amino Acids 2011 Oct;41(4):863-73. Epub 2010 feb 24
PMID: 20177948
Signal transduction mechanisms involved in S100A4-induced activation of the transcription factor NF-kappaB.
BMC Cancer 2010;10():241. Epub 2010 mai 28
PMID: 20507646 - Inngår i doktorgradsavhandlingen
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Signal transduction induced by the metastasis associated protein S100A4; Activation of NF-kB and EGFR
- Disputert:
- oktober 2013
- Hovedveileder:
- Gunhild Mari Mælandsmo
- Lina Prasmickaite Hovedveileder
- Ingrid Johanne Bettum Doktorgradsstipendiat
- Gunhild Mælandsmo Hovedveileder
- Kjetil Boye Biveileder
- Ida Grotterød Doktorgradsstipendiat
- Solveig Pettersen Prosjektdeltaker
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
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