National Core Facility for Human Pluripotent Stem Cells
- Prosjektnummer
- 2011014
- Ansvarlig person
- Joel C. Glover
- Institusjon
- Oslo universitetssykehus HF
- Prosjektkategori
- Regional teknologisk kjernefasilitet
- Helsekategori
- Generic Health Relevance
- Forskningsaktivitet
- 1. Underpinning
Investigation of Rett syndrome using pluripotent stem cells.
J Cell Biochem 2013 Nov;114(11):2446-53.
PMID: 23744605
Comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells".
Sci Transl Med 2013 Jun 5;5(188):188le2.
PMID: 23740897
Modelling human disease with pluripotent stem cells.
Curr Gene Ther 2013 Apr;13(2):99-110.
PMID: 23444871
A neonatal mouse spinal cord injury model for assessing post-injury adaptive plasticity and human stem cell integration.
PLoS One 2013;8(8):e71701. Epub 2013 aug 19
PMID: 23990976
Inhibition of tumor formation and redirected differentiation of glioblastoma cells in a xenotypic embryonic environment.
Dev Dyn 2013 Sep;242(9):1078-93. Epub 2013 jul 29
PMID: 23780720
EGF signalling and rapamycin-mediated mTOR inhibition in glioblastoma multiforme evaluated by phospho-specific flow cytometry.
J Neurooncol 2013 Mar;112(1):49-57. Epub 2013 jan 9
PMID: 23299461
Epigenetic regulation of nestin expression during neurogenic differentiation of adipose tissue stem cells.
Stem Cells Dev 2013 Apr 1;22(7):1042-52. Epub 2012 des 21
PMID: 23140086
Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells.
BMC Genomics 2013;14():105. Epub 2013 feb 15
PMID: 23414147
The role of paracrine and autocrine signaling in the early phase of adipogenic differentiation of adipose-derived stem cells.
PLoS One 2013;8(5):e63638. Epub 2013 mai 28
PMID: 23723991
Comparison of glioma stem cells to neural stem cells from the adult human brain identifies dysregulated Wnt- signaling and a fingerprint associated with clinical outcome.
Exp Cell Res 2013 Aug 15;319(14):2230-43. Epub 2013 jun 18
PMID: 23791939
Expansion of multipotent stem cells from the adult human brain.
PLoS One 2013;8(8):e71334. Epub 2013 aug 14
PMID: 23967194
Recruited brain tumor-derived mesenchymal stem cells contribute to brain tumor progression.
Stem Cells 2014 May;32(5):1110-23.
PMID: 24302539
Evaluation of intracellular labeling with micron-sized particles of iron oxide (MPIOs) as a general tool for in vitro and in vivo tracking of human stem and progenitor cells.
Cell Transplant 2012;21(8):1743-59. Epub 2012 mar 27
PMID: 22490338
[In Process Citation].
Tidsskr Nor Laegeforen 2012 Dec;132(23):2584.
PMID: 23338066
Ectopic expression of CDX4 in human mesenchymal stem cells does not affect HOX gene expression or induce hematopoietic reprogramming.
Stem Cell Res 2012 Sep;9(2):135-42. Epub 2012 mai 29
PMID: 22721648
Humanized murine model for HBV and HCV using human induced pluripotent stem cells.
Arch Pharm Res 2012 Feb;35(2):261-9. Epub 2012 feb 28
PMID: 22370780
Cellular reprogramming: a novel tool for investigating autism spectrum disorders.
Trends Mol Med 2012 Aug;18(8):463-71. Epub 2012 jul 6
PMID: 22771169
FUS-SMN protein interactions link the motor neuron diseases ALS and SMA.
Cell Rep 2012 Oct;2(4):799-806. Epub 2012 sep 27
PMID: 23022481
Organization of functional synaptic connections between medullary reticulospinal neurons and lumbar descending commissural interneurons in the neonatal mouse.
J Neurosci 2011 Mar;31(12):4731-42.
PMID: 21430172
Novel synthetic antagonists of canonical Wnt signaling inhibit colorectal cancer cell growth.
Cancer Res 2011 Jan;71(1):197-205.
PMID: 21199802
A novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse model.
PLoS One 2011;6(6):e19904. Epub 2011 jun 15
PMID: 21698280
Protein phosphatase 1 regulators in DNA damage signaling.
Cell Cycle 2011 May;10(9):1356-62. Epub 2011 mai 1
PMID: 21451260
Zebrafish mRNA sequencing deciphers novelties in transcriptome dynamics during maternal to zygotic transition.
Genome Res 2011 Aug;21(8):1328-38. Epub 2011 mai 9
PMID: 21555364
cAMP induces autophagy via a novel pathway involving ERK, cyclin E and Beclin 1.
Autophagy 2011 Oct;7(10):1199-211. Epub 2011 okt 1
PMID: 21750416
Remodeling of ribosomal genes in somatic cells by Xenopus egg extract.
Biochem Biophys Res Commun 2011 Sep;412(3):487-93. Epub 2011 aug 6
PMID: 21843509
A chromatin immunoprecipitation protocol for small cell numbers.
Methods Mol Biol 2011;791():179-93.
PMID: 21913080
Prepatterning of developmental gene expression by modified histones before zygotic genome activation.
Dev Cell 2011 Dec;21(6):993-1004. Epub 2011 des 1
PMID: 22137762
Effect of three-dimensional culture and incubator gas concentration on phenotype and differentiation capability of human mesenchymal stem cells.
J Cell Biochem 2011 Feb;112(2):684-93.
PMID: 21268090
Importance of serum source for the in vitro replicative senescence of human bone marrow derived mesenchymal stem cells.
J Cell Physiol 2011 Nov;226(11):2908-15.
PMID: 21302288
Human adipose tissue as a source of cells with angiogenic potential.
Cell Transplant 2012;21(1):235-50. Epub 2011 jun 7
PMID: 21669039
Stem cells for cardiac repair in acute myocardial infarction.
Expert Rev Cardiovasc Ther 2011 Aug;9(8):1015-25.
PMID: 21878046
Spectroscopic study of explanted opacified hydrophilic acrylic intraocular lenses.
Acta Ophthalmol 2011 Mar;89(2):e161-6.
PMID: 20491688
Predifferentiated brain-derived adult human progenitor cells migrate toward ischemia after transplantation to the adult rat brain.
Neurosurgery 2011 Jan;68(1):213-22; discussion 222.
PMID: 21099718
A comparative study of the structural organization of spheres derived from the adult human subventricular zone and glioblastoma biopsies.
Exp Cell Res 2011 Apr;317(7):1049-59. Epub 2011 jan 1
PMID: 21199649
Surgical mortality at 30 days and complications leading to recraniotomy in 2630 consecutive craniotomies for intracranial tumors.
Neurosurgery 2011 May;68(5):1259-68; discussion 1268-9.
PMID: 21273920
The Brain-Computer Interface.
World Neurosurg 2011 Nov. Epub 2011 nov 1
PMID: 22120219
Tumor-infiltrating macrophages are associated with metastasis suppression in high-grade osteosarcoma: a rationale for treatment with macrophage activating agents.
Clin Cancer Res 2011 Apr;17(8):2110-9. Epub 2011 mar 3
PMID: 21372215
MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines.
BMC Cancer 2011;11():211:1-11. Epub 2011 mai 30
PMID: 21624110
Adipocyte differentiation of human bone marrow-derived stromal cells is modulated by microRNA-155, microRNA-221, and microRNA-222.
Stem Cells Dev 2012 Apr;21(6):873-83. Epub 2011 aug 24
PMID: 21756067
mRNA expression profiles of primary high-grade central osteosarcoma are preserved in cell lines and xenografts.
BMC Med Genomics 2011;4():66. Epub 2011 sep 20
PMID: 21933437
Genome wide single cell analysis of chemotherapy resistant metastatic cells in a case of gastroesophageal adenocarcinoma.
BMC Cancer 2011;11():455. Epub 2011 okt 20
PMID: 22014070
A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA.
Nucleic Acids Res 2011 Apr;39(8):e55. Epub 2011 feb 7
PMID: 21300643
Modeling the impact of mitochondrial DNA damage in forebrain neurons and beyond.
Mech Ageing Dev 2011 Aug;132(8-9):424-8. Epub 2011 feb 25
PMID: 21354441
Uracil-DNA glycosylase of Thermoplasma acidophilum directs long-patch base excision repair, which is promoted by deoxynucleoside triphosphates and ATP/ADP, into short-patch repair.
J Bacteriol 2011 Sep;193(17):4495-508. Epub 2011 jun 10
PMID: 21665970
The presence of 5-hydroxymethylcytosine at the gene promoter and not in the gene body negatively regulates gene expression.
Biochem Biophys Res Commun 2011 Jul;411(1):40-3. Epub 2011 jun 15
PMID: 21703242
X-linked Angelman-like syndrome caused by Slc9a6 knockout in mice exhibits evidence of endosomal-lysosomal dysfunction.
Brain 2011 Nov;134(Pt 11):3369-83. Epub 2011 sep 29
PMID: 21964919
The ada operon of Mycobacterium tuberculosis encodes two DNA methyltransferases for inducible repair of DNA alkylation damage.
DNA Repair (Amst) 2011 Jun;10(6):595-602. Epub 2011 mai 12
PMID: 21570366
Mitochondrial DNA damage level determines neural stem cell differentiation fate.
J Neurosci 2011 Jun;31(26):9746-51.
PMID: 21715639
Schizosaccharomyces pombe Ofd2 is a nuclear 2-oxoglutarate and iron dependent dioxygenase interacting with histones.
PLoS One 2011;6(9):e25188. Epub 2011 sep 16
PMID: 21949882
A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression.
Proc Natl Acad Sci U S A 2011 Nov;108(46):18748-53. Epub 2011 okt 31
PMID: 22042866
AP endonuclease independent repair of abasic sites in Schizosaccharomyces pombe.
Nucleic Acids Res 2011 Nov. Epub 2011 nov 13
PMID: 22084197
The role of plerixafor in optimizing peripheral blood stem cell mobilization for autologous stem cell transplantation.
Leukemia 2011 Jan;25(1):1-6.
PMID: 21224858
High dose chemotherapy with autologous stem cell support for patients with histologically transformed B-cell non-Hodgkin lymphomas. A Norwegian multi centre phase II study.
Br J Haematol 2011 Mar;152(5):600-10. Epub 2011 jan 17
PMID: 21241276
Mycoplasma contamination revisited: mesenchymal stromal cells harboring Mycoplasma hyorhinis potently inhibit lymphocyte proliferation in vitro.
PLoS One 2011;6(1):e16005. Epub 2011 jan 11
PMID: 21264307
hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes.
Cancer Immunol Immunother 2011 Jun;60(6):809-18. Epub 2011 mar 2
PMID: 21365467
Side population cells in highly enriched CD34-positive cells from peripheral blood progenitor cells identify an immature subtype of hematopoietic progenitor cells but do not predict time to engraftment in patients treated with high-dose therapy.
Eur J Haematol 2011 Dec;87(6):494-502. Epub 2011 sep 15
PMID: 21752097
The mild inflammatory response in febrile neutropenic lymphoma patients with low risk of complications is more pronounced in patients receiving tobramycin once daily compared with three times daily.
Scand J Immunol 2011 Dec;74(6):632-9.
PMID: 21883353
The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation.
Adv Pharmacol Sci 2011;2011():157015. Epub 2011 sep 6
PMID: 21912538
Prostate Cancer Cell Lines under Hypoxia Exhibit Greater Stem-Like Properties.
PLoS One 2011;6(12):e29170. Epub 2011 des 28
PMID: 22216200
Fra science fiction til nobelpris
Aftenposten 17. oktober 2012.
Norwegian Expertise in Stem Cell Research
Public Service Review, Science and Technology
Characterization of stem cell-enriched glioblastoma cells in vitro and in xenotypic tissue environments
- Disputert:
- desember 2013
- Hovedveileder:
- Joel Glover
In vitro chondrogenesis. The role of microRNAs during differentiation and dedifferentiation
- Disputert:
- juni 2013
- Hovedveileder:
- Jan E. Brinchmann
Physiological Roles of Mouse Alkbh7: Implications in Obesity and Running Endurance
- Disputert:
- august 2013
- Hovedveileder:
- Arne Klungland
Tissue engineering of hyaline cartilage. Genome-wide investigation of molecular mechanisms during in vitro chondrogenesis
- Disputert:
- september 2013
- Hovedveileder:
- Jan E. Brinchmann
Novel approaches to the treatment of high grade sarcomas
- Disputert:
- mai 2011
- Hovedveileder:
- Ola Myklebost
Propagation and characterization of stem like cells from brain tumors - establishment of a clinical protocol for immunotherapeut
- Disputert:
- mai 2011
- Hovedveileder:
- Iver Langmoen
Epigenetic landscape of pluripotency-associated genes in human cells
- Disputert:
- mai 2011
- Hovedveileder:
- Philippe Collas
Alkbh8-mediated formation of wobble uridine modifications
- Disputert:
- oktober 2011
- Hovedveileder:
- Arne Klungland
Excision repair deficiencies in man and mice; lessons from CSA and Fen1 mutants
- Disputert:
- desember 2011
- Hovedveileder:
- Arne Klungland
- Leif Roger Hjeldnes Prosjektdeltaker
- Tabea Sinkovic Prosjektdeltaker
- Monika Gelazauskaite Prosjektdeltaker
- Hege Brincker Fjerdingstad Prosjektdeltaker
- Gareth Sullivan Forskningsgruppeleder
- Joel Glover Prosjektleder
eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT
Alle henvendelser rettes til eRapport