Helse Sør-Øst Research Group in Rheumatology with a focus on inflammatory joint diseases

Prosjektnummer: 2011100
Ansvarlig person: Tore K Kvien
Institusjon: Diakonhjemmet Sykehus AS
Prosjektkategori: Helse Sør-Øst forskningsgruppe
Helsekategori: Musculoskeletal
Forskningsaktivitet: 7. Disease Management

2013 - sluttrapport

Leddgikt og beslektede sykdommer rammer 1-2 prosent av befolkningen og fører blant annet til smerter og progredierende funksjonstap. Heldigvis er det de siste årene kommet bedre evidensbaserte behandlingsstrategier. Forskningsgruppen i revmatologi har fremskaffet nye forskningsresultater som kommer pasientbehandlingen til gode. Forskningsgruppe i revmatologi har brukt forskningsmidlene i 2012 til å lønne stipendiater, styrke infrastruktur (statistiker, forskningssykepleiere, forskningskoordinator) og til drift (reagenser knyttet til translasjonsforskning, utstyr til å måle surrogatmarkører for kardiovaskulære endepunkter). Forskningsproduksjonen er omfattende og samtidig medvirker en rekke av forskningsgruppens deltakere i store internasjonale prosjekter. Fokus for forskningsgruppen er klinisk forskning på leddgikt og beslektede sykdommer som kan bidra til ny kunnskap av betydning for pasientbehandlingen. Følgende områder har hatt sterkest fokus: Tidlig artritt: Mer enn 1500 pasienter er inkludert og følges longitudinelt. Dette forskningsområdet er nå også integrert i regionalt forskningsnettverk (NOR-VEAC). Revmatoid artritt: Kliniske data fra ulike kohorter har gitt ny kunnskap om prediktorer for sykdomsforløp og remisjon som behandlingsmål. NOR-DMARD: Longitudinell multisenter observasjonsstudie av mer enn 12000 pasienter som starter sykdomsmodifiserende legemidler og som har resultert i flere viktige publikasjoner om behandlingseffekt, men også med relevans for helseøkonomi. En PhD stipendiat lønnes fra forskningsgruppemidlene leverer sitt PhD arbeid tidlig 2014. Fokus har vært bruk av biologiske legemidler ved psoriasisartritt og ankyloserende spondylitt. BEKHAM og SPACE: Pasienter med ankyloserende spondylitt følges longitudinelt i BEKHAM prosjektet med et økende fokus på kardiovaskulære endepunkter. En PhD stipendiat lønnet fra forskningsgruppemidlene leverer sitt PhD arbeid høsten 2014. Fokus har vært bruk av kardiovaskulær morbiditet hos pasienter med ankyloserende spondylitt. SPACE har fokus på tidlig diagnose inkludert ikke-radiografisk aksial spondyloartritt. Kardiovaskulære utfall: Pasienter er undersøkt med tanke på surrogatmarkører for kardiovaskulære endepunkter og flere nye prosjekter er startet, inkludert en intervensjonsstudie med statiner og en klinikk med fokus på forebygging kardiovaskulær sykdom. Genetiske markører og løselige biomarkører: Er undersøkt med tanke på sykdomsassosiasjon og prediktorer for sykdomsprogresjon og sykdomsutfall. Billedmodaliteter: Ultralyd og MR brukes som utfallsvariabler og prediktorer for sykdomsforløp, både ved artritt sykdommer og håndartrose. Rehabilitering og kliniske utfallsmål: Flere studier er gjennomført med fokus på kartlegging av pasienters funksjonsnivå innenfor ulike dimensjoner av helse, og kontrollerte intervensjonsstudier er gjennomført for bl.a. å undersøke effekt av livsstyrketrening. En stor multisenter RCT – ARCTIC – er startet og sammenlikner et klinisk og et ultralyd styrt behandlingsmål (to strategier) med tanke på senere progresjon av beindestruksjon (inklusjon fullført med 11 deltakende sentra i Norge). En nedtrappingsstudie for biologiske legemidler hos pasienter i remisjon er også startet (ARCTIC-REWIND). Prosjektene som gjennomføres har generelt gitt ny kunnskap om prediktorer for ulike typer sykdomsforløp og styrket muligheter for individualisert behandling. I tidlig artritt prosjektet og i rehabiliteringsprosjekter har man etablert et samarbeid med primærhelsetjenesten og med brukere som kan ha overføringsverdi til andre deler av helsevesenet. Ny kunnskap fra NOR-DMARD når det gjelder betydning av tidlig behandling og på lavere sykdomsaktivitetsnivå har betydning fordi man oppnår bedre resultater (høyere remisjonsrate). Disse funnene har overføringsverdi til andre miljøer både nasjonalt og internasjonalt. Innenfor billeddiagnostikk er det utviklet nye validerte skåringssystemer som er av betydning for ulike intervensjonsstudier. Den opprettede forebyggende hjerte-revma klinikken har vist at det er mulig å fokusere på inflammasjon og dessuten konvensjonelle risikofaktorer for kardiovaskulær sykdom hos pasienter med leddgikt og beslektede sykdommer, og etablere forebyggingstiltak knyttet til lipider, blodtrykk og livsstil. Vi mener at flere av prosjektene har ført til bedre behandlings rutiner som derfor kommer inn under innovasjonsbegrepet. Det gjelder for eksempel prosjekter innenfor tidlig artritt, rehabilitering, billedmodaliteter, kardiovaskulære komplikasjoner, ARCTIC, ARCTIC-REWIND og NOR-DMARD. Imidlertid har ikke prosjektene ført til innovasjonsrealisering som er nevnt nedenfor.

2012

Helse Sør-Øst forskningsgruppe i revmatologiLeddgikt og beslektede sykdommer rammer 1-2 prosent av befolkningen og fører blant annet til smerter og progredierende funksjonstap. Heldigvis er det de siste årene kommet bedre evidensbaserte behandlingsstrategier. Forskningsgruppen i revmatologi har fremskaffet nye forskningsresultater som kommer pasientbehandlingen til gode.Forskningsgruppe i revmatologi har brukt forskningsmidlene i 2012 til å lønne stipendiater, styrke infrastruktur (statistiker, forskningssykepleiere, forskningskoordinator) og til drift (reagenser knyttet til translasjonsforskning, utstyr til å måle surrogatmarkører for kardiovaskulære endepunkter). Forskningsproduksjonen er omfattende og samtidig medvirker en rekke av forskningsgruppens deltakere i store internasjonale prosjekter. Fokus for forskningsgruppen er pasientnær klinisk forskning på leddgikt og beslektede sykdommer med et hovedfokus på følgende områder: Tidlig artritt: Mer enn 1100 pasienter er inkludert og følges longitudinelt. Dette forskningsområdet er videreført i regionalt forskningsnettverk (NOR-VEAC). Revmatoid artritt: Kliniske data fra ulike kohorter har gitt ny kunnskap om prediktorer for sykdomsforløp og remisjon som behandlingsmål. NOR-DMARD: Longitudinell multisenter observasjonsstudie av 11000 pasienter som starter sykdomsmodifiserende legemidler og som har resultert i flere viktige publikasjoner om behandlingseffekt, men også med relevans for helseøkonomi. BEKHAM og SPACE: Pasienter med Bekhterev sykdom longitudinelt med et økende fokus på kardiovaskulære endepunkter. SPACE har fokus på tidlig diagnose. Kardiovaskulære utfall: Pasienter er undersøkt med tanke på surrogatmarkører for kardiovaskulære endepunkter og flere nye prosjekter er startet, inkludert en intervensjonsstudie med statiner og en klinikk med fokus på forebygging kardiovaskulær sykdom. Genetiske markører og løselige biomarkører: Er undersøkt med tanke på sykdomsassosiasjon og prediktorer for sykdomsprogresjon og sykdomsutfall. Billedmodaliteter: Ultralyd og MR brukes som utfallsvariabler og prediktorer for sykdomsforløp, både ved artritt sykdommer og håndartrose. Rehabilitering og kliniske utfallsmål: Flere studier er gjennomført med fokus på kartlegging av pasienters funksjonsnivå innenfor ulike dimensjoner av helse, og kontrollerte intervensjonsstudier er gjennomført for bl.a. å undersøke effekt av livsstyrketrening. En stor multisenter RCT – ARCTIC – er startet og sammenlikner et klinisk og et ultralyd styrt behandlingsmål (to strategier) med tanke på senere progresjon av beindestruksjon. Prosjektene som gjennomføres har generelt gitt ny kunnskap om prediktorer for ulike typer sykdomsforløp. I tidlig artritt prosjektet har man etablert et samarbeid med primærhelsetjenesten og med brukere som kan ha overføringsverdi til andre deler av helsevesenet. Ny kunnskap fra NOR-DMARD har også slik overføringsverdi til andre miljøer både nasjonalt og internasjonalt. Innenfor billeddiagnostikk er det utviklet nye validerte skåringssystemer.

2011

Helse Sør-Øst Forskningsgruppe Revmatologi for bedre helseLeddgikt og beslektede sykdommer rammer 1-2 prosent av befolkningen og fører blant annet til smerter og progredierende funksjonstap. Heldigvis er det de siste årene kommet bedre evidensbaserte behandlingsstrategier. Forskningsgruppen i revmatologi har muliggjort nye forskningsresultater som kommer pasientbehandlingen til gode.Forskningsmidlene i relasjon til forskningsgruppe i revmatologi har vært brukt til å lønne stipendiater, styrke infrastruktur (statistiker, forskningssykepleiere, forskningskoordinator) og til drift (reagenser knyttet til translasjonsforskning, utstyr til å måle surrogatmarkører for kardiovaskulære endepunkter). Forskningsproduksjonen øker og samtidig medvirker en rekke av forskningsgruppens deltakere i store internasjonale prosjekter. Fokus for forskningsgruppen er pasientnær klinisk forskning på leddgikt og beslektede sykdommer med et hovedfokus på følgende områder: Tidlig artritt: Mer enn 1100 pasienter er inkludert og følges longitudinelt. Revmatoid artritt: Biobankmateriale og kliniske data fra ORAR, EURIDISS og data fra BRASS kohorten i Boston har gitt ny kunnskap om prediktorer for sykdomsforløp og remisjon som behandlingsmål. NOR-DMARD: Longitudinell multisenter observasjonsstudie av 11000 pasienter som starter sykdomsmodifiserende legemidler og som har resultert i flere viktige publikasjoner om behandlingseffekt, men også med relevans for helseøkonomi. BEKHAM og SPACE: Pasienter med Bekhterev sykdom som følges longitudinelt med et økende fokus på kardiovaskulære endepunkter. Kardiovaskulære utfall: Pasienter er undersøkt med tanke på surrogatmarkører for kardiovaskulære endepunkter og flere nye prosjekter er startet, inkludedert en intervensjonsstudie med statiner. Dessuten er det gjennomført eksplorative analyser av pasienter med leddgikt og beslektede sykdommer i store intervensjonsstudier (AMORIS, TNT, CARDS, IDEAL) Genetiske markører og løselige biomarkører: Er undersøkt som prediktorer for sykdomsprogresjon og sykdomsutfall. Billedmodaliteter: Ultralyd og MR brukes som utfallsvariabler og prediktorer for sykdomsforløp. Håndartrose. Viktig forskning er gjennomført for å standardisere utfallsmål ved bruk av MRI. En stor multisenter RCT – ARCTIC – er startet og sammenlikner et klinisk og et ultralyd styrt behandlingsmål (to strategier) med tanke på senere progresjon av beindestruksjon. Prosjektene som gjennomføres har generelt gitt ny kunnskap om prediktorer for ulike typer sykdomsforløp og bidratt til utvikling av algoritmer som kan brukes for å individualisere pasientbehandlingen (basert på kliniske variabler, billeddiagnostikk, genetiske markører og løselige biomarkører). I tidlig artritt prosjektet har man etablert et tettere samarbeid med primærhelsetjenesten som kan ha overføringsverdi. Ny kunnskap fra NOR-DMARD har også slik overføringsverdi til andre miljøer både nasjonalt og internasjonalt. Innenfor billeddiagnostikk er det utviklet nye validerte skåringssystemer.

Vitenskapelige artikler

Maehlen MT, Olsen IC, Andreassen BK, Viken MK, Jiang X, Alfredsson L, Källberg H, Brynedal B, Kurreeman F, Daha N, Toes R, Zhernakova A, Gutierrez-Achury J, de Bakker PI, Martin J, Teruel M, Gonzalez-Gay MA, Rodríguez-Rodríguez L, Balsa A, Uhlig T, Kvien TK, Lie BA

Genetic risk scores and number of autoantibodies in patients with rheumatoid arthritis.

Ann Rheum Dis 2015 Apr;74(4):762-8. Epub 2013 des 13

PMID: 24336335

Aga AB, Lie E, Uhlig T, Olsen IC, Wierød A, Kalstad S, Rødevand E, Mikkelsen K, Kvien TK, Haavardsholm EA

Time trends in disease activity, response and remission rates in rheumatoid arthritis during the past decade: results from the NOR-DMARD study 2000-2010.

Ann Rheum Dis 2015 Feb;74(2):381-8. Epub 2013 nov 27

PMID: 24285493

Conaghan Philip G, Bijlsma Johannes W, Kneer Werner, Wise Elspeth, Kvien Tore K, Rother Matthias

Drug-free gel containing ultra-deformable phospholipid vesicles (TDT 064) as topical therapy for the treatment of pain associated with osteoarthritis: a review of clinical efficacy and safety.

Curr Med Res Opin 2013 Nov 26. Epub 2013 nov 26

PMID: 24164189

Austad C, Kvien TK, Olsen IC, Uhlig T

Health status has improved more in women than in men with rheumatoid arthritis from 1994 to 2009: results from the Oslo rheumatoid arthritis register.

Ann Rheum Dis 2015 Jan;74(1):148-55. Epub 2013 okt 15

PMID: 24130265

Putrik Polina, Ramiro Sofia, Kvien Tore K, Sokka Tuulikki, Uhlig Till, Boonen Annelies, Equity in Clinical Eligibility Criteria for RA treatment Working Group

Variations in criteria regulating treatment with reimbursed biologic DMARDs across European countries. Are differences related to country's wealth?

Ann Rheum Dis 2014 Nov;73(11):2010-21. Epub 2013 aug 12

PMID: 23940213

Lie Elisabeth, Woodworth Thasia G, Christensen Robin, Kvien Tore K, Bykerk Vivien, Furst Daniel E, Bingham Clifton O, Choy Ernest H, the OMERACT RA Flare Working Group

Validation of OMERACT preliminary rheumatoid arthritis flare domains in the NOR-DMARD study.

Ann Rheum Dis 2013 Jul 12. Epub 2013 jul 12

PMID: 23852690

Garratt Andrew M, Løchting Ida, Smedslund Geir, Hagen Kåre B

Measurement properties of instruments assessing self-efficacy in patients with rheumatic diseases.

Rheumatology (Oxford) 2014 Jul;53(7):1161-71. Epub 2013 nov 18

PMID: 24249031

Hermann Merete, Nilsen Tove, Eriksen Camilla S, Slatkowsky-Christensen Barbara, Haugen Ida Kristin, Kjeken Ingvild

Effects of a soft prefabricated thumb orthosis in carpometacarpal osteoarthritis.

Scand J Occup Ther 2014 Jan;21(1):31-9. Epub 2013 nov 11

PMID: 24215554

Niedermann Karin, Sidelnikov Eduard, Muggli Claudia, Dagfinrud Hanne, Hermann Matthias, Tamborrini Giorgio, Ciurea Adrian, Bischoff-Ferrari Heike

Cardiovascular training improves fitness in patients with ankylosing spondylitis.

Arthritis Care Res (Hoboken) 2013 Jul 8. Epub 2013 jul 8

PMID: 23836515

Ndosi Mwidimi, Bremander Ann, Hamnes Bente, Horton Mike, Kukkurainen Marja Leena, Machado Pedro, Marques Andrea, Meesters Jorit, Stamm Tanja A, Tennant Alan, de la Torre-Aboki Jenny, Vliet Vlieland Theodora P M, Zangi Heidi A, Hill Jackie

Validation of the educational needs assessment tool as a generic instrument for rheumatic diseases in seven European countries.

Ann Rheum Dis 2014 Dec;73(12):2122-9. Epub 2013 aug 6

PMID: 23921996

Smedslund Geir, Eide Hilde, Kristjansdottir Ólöf Birna, Nes Andrea Aparecida Gonçalves, Sexton Harold, Fors Egil A

Do weather changes influence pain levels in women with fibromyalgia, and can psychosocial variables moderate these influences?

Int J Biometeorol 2014 Sep;58(7):1451-7. Epub 2013 okt 17

PMID: 24132549

Stoffer Michaela A, Smolen Josef S, Woolf Anthony, Ambrozic Ales, Bosworth Ailsa, Carmona Loreto, Fialka-Moser Veronika, Loza Estibaliz, Olejnik Pawel, Petersson Ingemar F, Uhlig Till, Stamm Tanja A, the eumusc.net-working group

Development of patient-centred standards of care for rheumatoid arthritis in Europe: the eumusc.net project.

Ann Rheum Dis 2013 Aug 6. Epub 2013 aug 6

PMID: 23921994

Petersson Ingemar F, Strömbeck Britta, Andersen Lene, Cimmino Marco, Greiff Rolf, Loza Estibaliz, Sciré Carlo, Stamm Tanja, Stoffer Michaela, Uhlig Till, Woolf Anthony D, Vliet Vlieland Theodora P M, the eumusc.net-working group

Development of healthcare quality indicators for rheumatoid arthritis in Europe: the eumusc.net project.

Ann Rheum Dis 2013 Aug 19. Epub 2013 aug 19

PMID: 23960093

Fernandes Linda, Hagen Kåre B, Bijlsma Johannes W J, Andreassen Oyvor, Christensen Pia, Conaghan Philip G, Doherty Michael, Geenen Rinie, Hammond Alison, Kjeken Ingvild, Lohmander L Stefan, Lund Hans, Mallen Christian D, Nava Tiziana, Oliver Susan, Pavelka Karel, Pitsillidou Irene, da Silva José Antonio, de la Torre Jenny, Zanoli Gustavo, Vliet Vlieland Theodora P M, European League Against Rheumatism (EULAR)

EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis.

Ann Rheum Dis 2013 Jul;72(7):1125-35. Epub 2013 apr 17

PMID: 23595142

Strömbeck Britta, Petersson Ingemar F, Vliet Vlieland Theodora P M, EUMUSC.net WP6 group

Health care quality indicators on the management of rheumatoid arthritis and osteoarthritis: a literature review.

Rheumatology (Oxford) 2013 Feb;52(2):382-90. Epub 2012 okt 19

PMID: 23086518

Dagfinrud H, Storheim K, Magnussen L H, Ødegaard T, Hoftaniska I, Larsen L G, Ringstad P O, Hatlebrekke F, Grotle M

The predictive validity of the Örebro Musculoskeletal Pain Questionnaire and the clinicians' prognostic assessment following manual therapy treatment of patients with LBP and neck pain.

Man Ther 2013 Apr;18(2):124-9. Epub 2012 sep 25

PMID: 23018081

Kjeken Ingvild, Darre Siri, Slatkowsky-Cristensen Barabara, Hermann Merete, Nilsen Tove, Eriksen Camilla S, Nossum Randi

Self-management strategies to support performance of daily activities in hand osteoarthritis.

Scand J Occup Ther 2013 Jan;20(1):29-36. Epub 2012 mar 1

PMID: 22376127

Løchting Ida, Fjerstad Elin, Garratt Andrew M

Illness perceptions in patients receiving rheumatology rehabilitation: association with health and outcomes at 12 months.

BMC Musculoskelet Disord 2013;14():28. Epub 2013 jan 16

PMID: 23324450

Kjeldsberg Mona, Tschudi-Madsen Hedda, Dalen Ingvild, Straand Jørund, Bruusgaard Dag, Natvig Bård

Symptom reporting in a general population in Norway: results from the Ullensaker study.

Scand J Prim Health Care 2013 Mar;31(1):36-42. Epub 2013 jan 7

PMID: 23293843

Uhlig Till, Sokka Tuulikki

'Rheumatologist go home!' Coming up next?

Ann Rheum Dis 2013 Jul;72(7):1111-2. Epub 2013 feb 20

PMID: 23426042

Smedslund Geir, Zangi Heidi Andersen, Mowinckel Petter, Hagen Kåre Birger

Two to five repeated measurements per patient reduced the required sample size considerably in a randomized clinical trial for patients with inflammatory rheumatic diseases.

BMC Res Notes 2013;6():37. Epub 2013 feb 1

PMID: 23374902

Østerås Nina, Risberg May Arna, Kvien Tore K, Engebretsen Lars, Nordsletten Lars, Bruusgaard Dag, Schjervheim Unni-Berit, Haugen Ida K, Hammer Hilde Berner, Provan Sella, Øiestad Britt Elin, Semb Anne Grete, Rollefstad Silvia, Hagen Kåre Birger, Uhlig Till, Slatkowsky-Christensen Barbara, Kjeken Ingvild, Flugsrud Gunnar, Grotle Margreth, Sesseng Sølve, Edvardsen Hanne, Natvig Bård

Hand, hip and knee osteoarthritis in a Norwegian population-based study--the MUST protocol.

BMC Musculoskelet Disord 2013;14():201. Epub 2013 jul 5

PMID: 23826721

Øiestad Britt Elin, Østerås Nina, Frobell Richard, Grotle Margreth, Brøgger Helga, Risberg May Arna

Efficacy of strength and aerobic exercise on patient-reported outcomes and structural changes in patients with knee osteoarthritis: study protocol for a randomized controlled trial.

BMC Musculoskelet Disord 2013;14():266. Epub 2013 sep 12

PMID: 24028201

Meesters Jorit, Hagel Sofia, Klokkerud Mari, Stovgaard Inger, Bremander Ann, Grotle Margreth, Hørslev-Petersen Kim, Petersson Ingemar F, Hagen Kåre Birger, Pont Winke, Vlieland Thea Vliet

Goal-setting in multidisciplinary team care for patients with rheumatoid arthritis: an international multi-center evaluation of the contents using the International Classification of Functioning, Disability and Health as a reference.

J Rehabil Med 2013 Sep;45(9):888-99.

PMID: 23974511

Klokkerud Mari, Grotle Margreth, Løchting Ida, Kjeken Ingvild, Hagen Kåre Birger, Garratt Andrew M

Psychometric properties of the Norwegian version of the patient generated index in patients with rheumatic diseases participating in rehabilitation or self-management programmes.

Rheumatology (Oxford) 2013 May;52(5):924-32. Epub 2013 jan 18

PMID: 23335634

Kjeken Ingvild, Bø Ingvild, Rønningen Aud, Spada Cristina, Mowinckel Petter, Hagen Kåre Birger, Dagfinrud Hanne

A three-week multidisciplinary in-patient rehabilitation programme had positive long-term effects in patients with ankylosing spondylitis: randomized controlled trial.

J Rehabil Med 2013 Mar 6;45(3):260-7.

PMID: 23138412

Halvorsen Silje, Vøllestad Nina Køpke, Provan Sella Arrestad, Semb Anne Grete, van der Heijde Désirée, Hagen Kåre Birger, Dagfinrud Hanne

Cardiorespiratory fitness and cardiovascular risk in patients with ankylosing spondylitis: a cross-sectional comparative study.

Arthritis Care Res (Hoboken) 2013 Jun;65(6):969-76.

PMID: 23281265

Grotle Margreth, Klokkerud Mari, Kjeken Ingvild, Bremander Ann, Hagel Sofia, Strömbeck Britta, Hørslev-Petersen Kim, Meesters Jorit, Vlieland Thea P M Vliet, Hagen Kåre B

What's in the black box of arthritis rehabilitation? A comparison of rehabilitation practice for patients with inflammatory arthritis in northern Europe.

J Rehabil Med 2013 May;45(5):458-66.

PMID: 23450275

Fongen Camilla, Halvorsen Silje, Dagfinrud Hanne

High disease activity is related to low levels of physical activity in patients with ankylosing spondylitis.

Clin Rheumatol 2013 Dec;32(12):1719-25. Epub 2013 jul 31

PMID: 23900575

Hiligsmann Mickaël, Cooper Cyrus, Arden Nigel, Boers Maarten, Branco Jaime C, Luisa Brandi Maria, Bruyère Olivier, Guillemin Francis, Hochberg Marc C, Hunter David J, Kanis John A, Kvien Tore K, Laslop Andrea, Pelletier Jean-Pierre, Pinto Daniel, Reiter-Niesert Susanne, Rizzoli René, Rovati Lucio C, Severens Johan L Hans, Silverman Stuart, Tsouderos Yannis, Tugwell Peter, Reginster Jean-Yves

Health economics in the field of osteoarthritis: an expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO).

Semin Arthritis Rheum 2013 Dec;43(3):303-13. Epub 2013 aug 29

PMID: 23992801

Haugen I K, Slatkowsky-Christensen B, Bøyesen P, van der Heijde D, Kvien T K

Cross-sectional and longitudinal associations between radiographic features and measures of pain and physical function in hand osteoarthritis.

Osteoarthritis Cartilage 2013 Sep;21(9):1191-8.

PMID: 23973130

Nordang Gry B N, Flåm Siri T, Maehlen Marthe T, Kvien Tore K, Viken Marthe K, Lie Benedicte A

HLA-C alleles confer risk for anti-citrullinated peptide antibody-positive rheumatoid arthritis independent of HLA-DRB1 alleles.

Rheumatology (Oxford) 2013 Nov;52(11):1973-82. Epub 2013 jul 30

PMID: 23901134

Maehlen Marthe T, Provan Sella A, de Rooy Diederik P C, van der Helm-van Mil Annette H M, Krabben Annemarie, Saxne Tore, Lindqvist Elisabet, Semb Anne Grete, Uhlig Till, van der Heijde Désirée, Mero Inger Lise, Olsen Inge C, Kvien Tore K, Lie Benedicte A

Associations between APOE genotypes and disease susceptibility, joint damage and lipid levels in patients with rheumatoid arthritis.

PLoS One 2013;8(4):e60970. Epub 2013 apr 17

PMID: 23613766

Austad C, Kvien T K, Uhlig T

Abdominal discomfort in patients with rheumatoid arthritis is associated with physical and mental function, self-reported disease activity, and use of anti-inflammatory medication.

Scand J Rheumatol 2013;42(4):333-5. Epub 2013 apr 14

PMID: 23581292

Fagerli Karen Minde, Lie Elisabeth, van der Heijde Désirée, Heiberg Marte Schrumpf, Kalstad Synøve, Rødevand Erik, Mikkelsen Knut, Lexberg Ase Stavland, Kvien Tore K

Switching between TNF inhibitors in psoriatic arthritis: data from the NOR-DMARD study.

Ann Rheum Dis 2013 Nov 1;72(11):1840-4. Epub 2013 apr 5

PMID: 23562987

Østerås Nina, Garratt Andrew, Grotle Margreth, Natvig Bård, Kjeken Ingvild, Kvien Tore K, Hagen Kåre B

Patient-reported quality of care for osteoarthritis: development and testing of the osteoarthritis quality indicator questionnaire.

Arthritis Care Res (Hoboken) 2013 Jul;65(7):1043-51.

PMID: 23401461

Koksvik Hege Svean, Hagen Kåre Birger, Rødevand Erik, Mowinckel Petter, Kvien Tore K, Zangi Heidi A

Patient satisfaction with nursing consultations in a rheumatology outpatient clinic: a 21-month randomised controlled trial in patients with inflammatory arthritides.

Ann Rheum Dis 2013 Jun;72(6):836-43. Epub 2013 feb 7

PMID: 23393144

van der Heijde Désirée, van der Helm-van Mil Annette H M, Aletaha Daniel, Bingham Clifton O, Burmester Gerd R, Dougados Maxime, Emery Paul, Felson David, Knevel Rachel, Kvien Tore K, Landewé Robert B M, Lukas Cédric, McInnes Iain, Silman Alan J, Smolen Josef S, Stanislawska-Biernat Ewa, Zink Angela, Combe Bernard

EULAR definition of erosive disease in light of the 2010 ACR/EULAR rheumatoid arthritis classification criteria.

Ann Rheum Dis 2013 Apr;72(4):479-81. Epub 2013 feb 2

PMID: 23378540

Semb Anne G, Rollefstad Silvia, Provan Sella A, Kvien Tore K, Stranden Einar, Olsen Inge C, Hisdal Jonny

Carotid plaque characteristics and disease activity in rheumatoid arthritis.

J Rheumatol 2013 Apr;40(4):359-68. Epub 2013 jan 15

PMID: 23322468

Rollefstad Silvia, Kvien Tore K, Holme Ingar, Eirheim Anne S, Pedersen Terje R, Semb Anne Grete P

Treatment to lipid targets in patients with inflammatory joint diseases in a preventive cardio-rheuma clinic.

Ann Rheum Dis 2013 Dec;72(12):1968-74. Epub 2012 des 22

PMID: 23264359

Dörner Thomas, Strand Vibeke, Castañeda-Hernández Gilberto, Ferraccioli Gianfranco, Isaacs John D, Kvien Tore K, Martin-Mola Emilio, Mittendorf Thomas, Smolen Josef S, Burmester Gerd R

The role of biosimilars in the treatment of rheumatic diseases.

Ann Rheum Dis 2013 Mar;72(3):322-8. Epub 2012 des 19

PMID: 23253920

Smolen Josef S, Schoels Monika M, Nishimoto Norihiro, Breedveld Ferdinand C, Burmester Gerd R, Dougados Maxime, Emery Paul, Ferraccioli Gianfranco, Gabay Cem, Gibofsky Allan, Gomez-Reino Juan Jesus, Jones Graeme, Kvien Tore K, Murakami Miho, Betteridge Neil, Bingham Clifton O, Bykerk Vivian, Choy Ernest H, Combe Bernard, Cutolo Maurizio, Graninger Winfried, Lanas Angel, Martin-Mola Emilio, Montecucco Carlomaurizio, Ostergaard Mikkel, Pavelka Karel, Rubbert-Roth Andrea, Sattar Naveed, Scholte-Voshaar Marieke, Tanaka Yoshiya, Trauner Michael, Valentini Gabriele, Winthrop Kevin L, De Wit Maarten, van der Heijde Désirée

Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions.

Ann Rheum Dis 2013 Apr;72(4):482-92. Epub 2012 nov 21

PMID: 23172750

Schoels Monika M, van der Heijde Désirée, Breedveld Ferdinand C, Burmester Gerd R, Dougados Maxime, Emery Paul, Ferraccioli Gianfranco, Gabay Cem, Gibofsky Allan, Gomez-Reino Juan Jesus, Jones Graeme, Kvien Tore K, Murakami Miho, Murikama Miho M, Nishimoto Norihiro, Smolen Josef S

Blocking the effects of interleukin-6 in rheumatoid arthritis and other inflammatory rheumatic diseases: systematic literature review and meta-analysis informing a consensus statement.

Ann Rheum Dis 2013 Apr;72(4):583-9. Epub 2012 nov 10

PMID: 23144446

Lillegraven Siri, Paynter Nina, Prince Femke H M, Shadick Nancy A, Haavardsholm Espen A, Frits Michelle L, Iannaccone Christine K, Kvien Tore K, Weinblatt Michael E, Solomon Daniel H

Performance of matrix-based risk models for rapid radiographic progression in a cohort of patients with established rheumatoid arthritis.

Arthritis Care Res (Hoboken) 2013 Apr;65(4):526-33.

PMID: 23044765

Helland Y, Garratt A, Kjeken I, Kvien T K, Dagfinrud H

Current practice and barriers to the management of sexual issues in rheumatology: results of a survey of health professionals.

Scand J Rheumatol 2013;42(1):20-6. Epub 2012 sep 21

PMID: 22994142

Moe Rikke H, Grotle Margreth, Kjeken Ingvild, Hagen Kåre B, Kvien Tore K, Uhlig Till

Disease impact of hand OA compared with hip, knee and generalized disease in specialist rheumatology health care.

Rheumatology (Oxford) 2013 Jan;52(1):189-96. Epub 2012 aug 25

PMID: 22923755

Mathiessen Alexander, Haugen Ida Kristin, Slatkowsky-Christensen Barbara, Bøyesen Pernille, Kvien Tore K, Hammer Hilde Berner

Ultrasonographic assessment of osteophytes in 127 patients with hand osteoarthritis: exploring reliability and associations with MRI, radiographs and clinical joint findings.

Ann Rheum Dis 2013 Jan;72(1):51-6. Epub 2012 apr 20

PMID: 22523427

Halvorsen Silje, Vøllestad Nina K, Fongen Camilla, Provan Sella A, Semb Anne G, Hagen Kåre B, Dagfinrud Hanne

Physical fitness in patients with ankylosing spondylitis: comparison with population controls.

Phys Ther 2012 Feb;92(2):298-309. Epub 2011 nov 17

PMID: 22095208

Nordang Gry B N, Viken Marte K, Amundsen Silja S, Sanchez Elena S, Flatø Berit, Førre Oystein T, Martin Javier, Kvien Tore K, Lie Benedicte A

Interferon regulatory factor 5 gene polymorphism confers risk to several rheumatic diseases and correlates with expression of alternative thymic transcripts.

Rheumatology (Oxford) 2012 Apr;51(4):619-26. Epub 2011 des 16

PMID: 22179739

Haugen Ida K, Cotofana Sebastian, Englund Martin, Kvien Tore K, Dreher Donatus, Nevitt Michael, Lane Nancy E, Eckstein Felix, eUtils.ItemsChoiceType2[]

Hand joint space narrowing and osteophytes are associated with magnetic resonance imaging-defined knee cartilage thickness and radiographic knee osteoarthritis: data from the Osteoarthritis Initiative.

J Rheumatol 2012 Jan;39(1):161-6. Epub 2011 nov 1

PMID: 22045837

Wallenius M, Skomsvoll J F, Irgens L M, Salvesen K Å, Nordvåg B-Y, Koldingsnes W, Mikkelsen K, Kaufmann C, Kvien T K

Parity in patients with chronic inflammatory arthritides childless at time of diagnosis.

Scand J Rheumatol 2012 May;41(3):202-7. Epub 2012 feb 24

PMID: 22360422

Pollmann Sylvie, Stensland Maria, Halvorsen Eirik Hornes, Sollid Ludvig M, Kvien Tore K, Fleckenstein Burkhard, Molberg Oyvind

Anti-PAD4 autoantibodies in rheumatoid arthritis: levels in serum over time and impact on PAD4 activity as measured with a small synthetic substrate.

Rheumatol Int 2012 May;32(5):1271-6. Epub 2011 jan 26

PMID: 21267570

Gossec L, Smolen J S, Gaujoux-Viala C, Ash Z, Marzo-Ortega H, van der Heijde D, FitzGerald O, Aletaha D, Balint P, Boumpas D, Braun J, Breedveld F C, Burmester G, Cañete J D, de Wit M, Dagfinrud H, de Vlam K, Dougados M, Helliwell P, Kavanaugh A, Kvien T K, Landewé R, Luger T, Maccarone M, McGonagle D, McHugh N, McInnes I B, Ritchlin C, Sieper J, Tak P P, Valesini G, Vencovsky J, Winthrop K L, Zink A, Emery P, eUtils.ItemsChoiceType2[]

European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies.

Ann Rheum Dis 2012 Jan;71(1):4-12. Epub 2011 sep 27

PMID: 21953336

Mandl Peter, Naredo Esperanza, Conaghan Philip G, D'Agostino Maria-Antonietta, Wakefield Richard J, Bachta Artur, Backhaus Marina, Hammer Hilde B, Bruyn George A W, Damjanov Nemanja, Filippucci Emilio, Grassi Walter, Iagnocco Annamaria, Jousse-Joulin Sandrine, Kane David, Koski Juhani M, Möller Ingrid, De Miguel Eugenio, Schmidt Wolfgang A, Swen Wijnand A A, Szkudlarek Marcin, Terslev Lene, Ziswiler Hans-Rudolf, Ostergaard Mikkel, Balint Peter V

Practice of ultrasound-guided arthrocentesis and joint injection, including training and implementation, in Europe: results of a survey of experts and scientific societies.

Rheumatology (Oxford) 2012 Jan;51(1):184-90. Epub 2011 nov 24

PMID: 22120466

Daha Nina A, Lie Benedicte A, Trouw L A, Stoeken Gerrie, Schonkeren Joris J M, Ding Bo, Kvien Tore K, Schilham Marco W, Padyukov Leonid, Huizinga T W J, Toes Rene

Novel genetic association of the VTCN1 region with rheumatoid arthritis.

Ann Rheum Dis 2012 Apr;71(4):567-71. Epub 2012 feb 9

PMID: 22323440

Lillegraven Siri, van der Heijde Désirée, Uhlig Till, Kvien Tore K, Haavardsholm Espen A

What is the clinical relevance of erosions and joint space narrowing in RA?

Nat Rev Rheumatol 2012 Feb;8(2):117-20. Epub 2012 jan 17

PMID: 22249163

Englbrecht Matthias, Gossec Laure, DeLongis Anita, Scholte-Voshaar Marieke, Sokka Tuulikki, Kvien Tore K, Schett Georg

The impact of coping strategies on mental and physical well-being in patients with rheumatoid arthritis.

Semin Arthritis Rheum 2012 Feb;41(4):545-55.

PMID: 22340997

Fagerhol Magne K, Larsen Annette, Brun Johan G, Hammer Hilde B, Angel Kristin, Kvien Tore K, Kinne Ingebjørg, Madland Tor M

Large molecular size EDTA-resistant complexes containing S100A12, ERAC, in serum during inflammatory conditions.

Scand J Clin Lab Invest 2012 Apr;72(2):129-36. Epub 2012 jan 17

PMID: 22248048

Hammer Hilde Berner, Haavardsholm Espen A

Advances in imaging.

Curr Opin Rheumatol 2012 May;24(3):299-305.

PMID: 22388645

Lie Elisabeth, Uhlig Till, van der Heijde Désirée, Rødevand Erik, Kalstad Synøve, Kaufmann Cecilie, Mikkelsen Knut, Kvien Tore K

Effectiveness of sulfasalazine and methotrexate in 1102 DMARD-naive patients with early RA.

Rheumatology (Oxford) 2012 Apr;51(4):670-8. Epub 2011 des 9

PMID: 22157597

Ronninger Marcus, Seddighzadeh Maria, Eike Morten Christoph, Plant Darren, Daha Nina A, Skinningsrud Beate, Worthington Jane, Kvien Tore K, Toes Rene E M, Lie Benedicte A, Alfredsson Lars, Padyukov Leonid

Interaction analysis between HLA-DRB1 shared epitope alleles and MHC class II transactivator CIITA gene with regard to risk of rheumatoid arthritis.

PLoS One 2012;7(3):e32861. Epub 2012 mar 26

PMID: 22461888

Eike M C, Skinningsrud B, Ronninger M, Stormyr A, Kvien T K, Joner G, Njølstad P R, Førre O, Flatø B, Alfredsson L, Padyukov L, Undlien D E, Lie B A

CIITA gene variants are associated with rheumatoid arthritis in Scandinavian populations.

Genes Immun 2012 Jul;13(5):431-6. Epub 2012 apr 19

PMID: 22513452

Fagerli Karen M, Lie Elisabeth, van der Heijde Désirée, Heiberg Marte S, Kaufmann Cecilie, Rødevand Erik, Mikkelsen Knut, Kalstad Synøve, Kvien Tore K

Selecting patients with ankylosing spondylitis for TNF inhibitor therapy: comparison of ASDAS and BASDAI eligibility criteria.

Rheumatology (Oxford) 2012 Aug;51(8):1479-83. Epub 2012 apr 11

PMID: 22499062

Angel Kristin, Provan Sella A, Fagerhol Magne K, Mowinckel Petter, Kvien Tore K, Atar Dan

Effect of 1-year anti-TNF-a therapy on aortic stiffness, carotid atherosclerosis, and calprotectin in inflammatory arthropathies: a controlled study.

Am J Hypertens 2012 Jun;25(6):644-50. Epub 2012 mar 1

PMID: 22378036

Olsen I C, Kvien T K, Uhlig T

Consequences of handling missing data for treatment response in osteoarthritis: a simulation study.

Osteoarthritis Cartilage 2012 Aug;20(8):822-8. Epub 2012 mar 19

PMID: 22441031

Aletaha Daniel, Martinez-Avila Jose, Kvien Tore K, Smolen Josef S

Definition of treatment response in rheumatoid arthritis based on the simplified and the clinical disease activity index.

Ann Rheum Dis 2012 Jul;71(7):1190-6. Epub 2012 mar 27

PMID: 22454398

Emery Paul, Kvien Tore K, Combe Bernard, Freundlich Bruce, Robertson Deborah, Ferdousi Tahmina, Bananis Eustratios, Pedersen Ronald, Koenig Andrew S

Combination etanercept and methotrexate provides better disease control in very early (<=4 months) versus early rheumatoid arthritis (>4 months and <2 years): post hoc analyses from the COMET study.

Ann Rheum Dis 2012 Jun;71(6):989-92. Epub 2012 mar 8

PMID: 22402142

Semb Anne Grete, Kvien Tore K, DeMicco David A, Fayyad Rana, Wun Chuan-Chuan, LaRosa John, Betteridge John, Pedersen Terje R, Holme Ingar

Prediction of cardiovascular events in patients with ankylosing spondylitis and psoriatic arthritis: role of lipoproteins in a high-risk population.

J Rheumatol 2012 Jul;39(7):1433-40. Epub 2012 jun 1

PMID: 22660802

van der Heijde Désirée, Keystone Edward C, Curtis Jeffrey R, Landewé Robert B, Schiff Michael H, Khanna Dinesh, Kvien Tore K, Ionescu Lucian, Gervitz Leon M, Davies Owen R, Luijtens Kristel, Furst Daniel E

Timing and magnitude of initial change in disease activity score 28 predicts the likelihood of achieving low disease activity at 1 year in rheumatoid arthritis patients treated with certolizumab pegol: a post-hoc analysis of the RAPID 1 trial.

J Rheumatol 2012 Jul;39(7):1326-33. Epub 2012 mai 15

PMID: 22589265

Gerlag Danielle M, Raza Karim, van Baarsen Lisa G M, Brouwer Elisabeth, Buckley Christopher D, Burmester Gerd R, Gabay Cem, Catrina Anca I, Cope Andrew P, Cornelis François, Dahlqvist Solbritt Rantapää, Emery Paul, Eyre Stephen, Finckh Axel, Gay Steffen, Hazes Johanna M, van der Helm-van Mil Annette, Huizinga Tom W J, Klareskog Lars, Kvien Tore K, Lewis Cathryn, Machold Klaus P, Rönnelid Johan, van Schaardenburg Dirkjan, Schett Georg, Smolen Josef S, Thomas Sue, Worthington Jane, Tak Paul P

EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis.

Ann Rheum Dis 2012 May;71(5):638-41. Epub 2012 mar 2

PMID: 22387728

Whittle Samuel L, Colebatch Alexandra N, Buchbinder Rachelle, Edwards Christopher J, Adams Karen, Englbrecht Matthias, Hazlewood Glen, Marks Jonathan L, Radner Helga, Ramiro Sofia, Richards Bethan L, Tarner Ingo H, Aletaha Daniel, Bombardier Claire, Landewé Robert B, Müller-Ladner Ulf, Bijlsma Johannes W J, Branco Jaime C, Bykerk Vivian P, da Rocha Castelar Pinheiro Geraldo, Catrina Anca I, Hannonen Pekka, Kiely Patrick, Leeb Burkhard, Lie Elisabeth, Martinez-Osuna Píndaro, Montecucco Carlomaurizio, Ostergaard Mikkel, Westhovens Rene, Zochling Jane, van der Heijde Désirée

Multinational evidence-based recommendations for pain management by pharmacotherapy in inflammatory arthritis: integrating systematic literature research and expert opinion of a broad panel of rheumatologists in the 3e Initiative.

Rheumatology (Oxford) 2012 Aug;51(8):1416-25. Epub 2012 mar 24

PMID: 22447886

Haugen Ida Kristin, Felson David T, Englund Martin, Wang Ke, Aliabadi Piran, Guermazi Ali, Roemer Frank W, Neogi Tuhina

The association between erosive hand osteoarthritis and subchondral bone attrition of the knee: the Framingham Osteoarthritis Study.

Ann Rheum Dis 2012 Oct;71(10):1698-701. Epub 2012 jun 23

PMID: 22730369

Nordang G B N, Carpenter D, Viken M K, Kvien T K, Armour J A L, Lie B A

Association analysis of the CCL3L1 copy number locus by paralogue ratio test in Norwegian rheumatoid arthritis patients and healthy controls.

Genes Immun 2012 Oct;13(7):579-82. Epub 2012 jul 12

PMID: 22785612

Angel Kristin, Provan Sella Aarrestad, Mowinckel Petter, Seljeflot Ingebjørg, Kvien Tore Kristian, Atar Dan

The l-arginine/asymmetric dimethylarginine ratio is improved by anti-tumor necrosis factor-a therapy in inflammatory arthropathies. Associations with aortic stiffness.

Atherosclerosis 2012 Nov;225(1):160-5. Epub 2012 sep 10

PMID: 23014354

Raza Karim, Saber Tajvur P, Kvien Tore K, Tak Paul P, Gerlag Danielle M

Timing the therapeutic window of opportunity in early rheumatoid arthritis: proposal for definitions of disease duration in clinical trials.

Ann Rheum Dis 2012 Dec;71(12):1921-3. Epub 2012 aug 31

PMID: 22941769

Hammer Hilde Berner, Terslev Lene

Role of ultrasound in managing rheumatoid arthritis.

Curr Rheumatol Rep 2012 Oct;14(5):438-44.

PMID: 22763856

Koski Juhani M, Hammer Hilde Berner

Ultrasound-guided procedures: techniques and usefulness in controlling inflammation and disease progression.

Rheumatology (Oxford) 2012 Dec;51 Suppl 7():vii31-5.

PMID: 23230092

Alcalde María, D'Agostino Maria Antonietta, Bruyn George A W, Möller Ingrid, Iagnocco Annamaria, Wakefield Richard J, Naredo Esperanza, eUtils.ItemsChoiceType2[]

A systematic literature review of US definitions, scoring systems and validity according to the OMERACT filter for tendon lesion in RA and other inflammatory joint diseases.

Rheumatology (Oxford) 2012 Jul;51(7):1246-60. Epub 2012 feb 29

PMID: 22378717

Dager Turid Nygaard, Kjeken Ingvild, Fjerstad Elin, Hauge Mona-Iren

"It is about taking grips and not let myself be ravaged by my body": a qualitative study of outcomes from in-patient multidisciplinary rehabilitation for patients with chronic rheumatic diseases.

Disabil Rehabil 2012;34(11):910-6. Epub 2011 nov 8

PMID: 22066740

Fernandes Linda, Storheim Kjersti, Lochting Ida, Grotle Margreth

Cross-cultural adaptation and validation of the Norwegian pain catastrophizing scale in patients with low back pain.

BMC Musculoskelet Disord 2012;13():111. Epub 2012 jun 22

PMID: 22726668

Eggen Marit Horst, Stuge Britt, Mowinckel Petter, Jensen Kjersti Smee, Hagen Kåre Birger

Can supervised group exercises including ergonomic advice reduce the prevalence and severity of low back pain and pelvic girdle pain in pregnancy? A randomized controlled trial.

Phys Ther 2012 Jun;92(6):781-90. Epub 2012 jan 26

PMID: 22282770

Fernandes Linda, Grotle Margreth, Darre Siri, Nossum Randi, Kjeken Ingvild

Validity and responsiveness of the Measure of Activity Performance of the Hand (MAP-Hand) in patients with hand osteoarthritis.

J Rehabil Med 2012 Oct;44(10):869-76.

PMID: 22948123

Grotle Margreth, Garratt Andrew M, Krogstad Jenssen Hanne, Stuge Britt

Reliability and construct validity of self-report questionnaires for patients with pelvic girdle pain.

Phys Ther 2012 Jan;92(1):111-23. Epub 2011 okt 20

PMID: 22016375

Hagen Kåre Birger, Dagfinrud Hanne, Moe Rikke Helene, Østerås Nina, Kjeken Ingvild, Grotle Margreth, Smedslund Geir

Exercise therapy for bone and muscle health: an overview of systematic reviews.

BMC Med 2012;10():167. Epub 2012 des 19

PMID: 23253613

Kjeken Ingvild

Measurement in occupational therapy.

Scand J Occup Ther 2012 Nov;19(6):466-7. Epub 2012 okt 1

PMID: 23025268

Klokkerud M, Hagen K B, Løchting I, Uhlig T, Kjeken I, Grotle M

Does the content really matter? A study comparing structure, process, and outcome of team rehabilitation for patients with inflammatory arthritis in two different clinical settings.

Scand J Rheumatol 2012 Feb;41(1):20-8. Epub 2011 nov 23

PMID: 22106920

Klokkerud Mari, Hagen Kåre Birger, Kjeken Ingvild, Bremander Ann, Hørslev-Petersen Kim, Vlieland Thea Vliet, Grotle Margreth, eUtils.ItemsChoiceType2[]

Development of a framework identifying domains and elements of importance for arthritis rehabilitation.

J Rehabil Med 2012 May;44(5):406-13.

PMID: 22549648

Løchting Ida, Garratt Andrew Malcolm, Klokkerud Mari, Fjerstad Elin

Development of the Rheumatic Disease Illness Perception Questionnaire (RD-IPQ) reliability, validity and responsiveness.

Clin Exp Rheumatol 2012 Mar-Apr;30(2):308. Epub 2012 apr 13

PMID: 22325016

Lund Anne, Michelet Mona, Kjeken Ingvild, Wyller Torgeir Bruun, Sveen Unni

Development of a person-centred lifestyle intervention for older adults following a stroke or transient ischaemic attack.

Scand J Occup Ther 2012 Mar;19(2):140-9. Epub 2011 aug 19

PMID: 21854103

Nilsen Tove, Hermann Merete, Eriksen Camilla S, Dagfinrud Hanne, Mowinckel Petter, Kjeken Ingvild

Grip force and pinch grip in an adult population: reference values and factors associated with grip force.

Scand J Occup Ther 2012 May;19(3):288-96. Epub 2011 feb 28

PMID: 21355705

Oesch Peter, Meyer Kathrin, Bachmann Stefan, Hagen Kåre Birger, Vøllestad Nina K

Comparison of two methods for interpreting lifting performance during functional capacity evaluation.

Phys Ther 2012 Sep;92(9):1130-40. Epub 2012 mai 31

PMID: 22652986

Oesch Peter, Meyer Kathrin, Jansen Beatrice, Mowinckel Petter, Bachmann Stefan, Hagen Kare Birger

What is the role of "nonorganic somatic components" in functional capacity evaluations in patients with chronic nonspecific low back pain undergoing fitness for work evaluation?

Spine (Phila Pa 1976) 2012 Feb;37(4):E243-50.

PMID: 21857400

Storheim Kjersti, Brox Jens Ivar, Løchting Ida, Werner Erik L, Grotle Margreth

Cross-cultural adaptation and validation of the Norwegian version of the Core Outcome Measures Index for low back pain.

Eur Spine J 2012 Dec;21(12):2539-49. Epub 2012 jun 14

PMID: 22695701

Skonnord Trygve, Skjeie Holgeir, Brekke Mette, Grotle Margreth, Lund Iréne, Fetveit Arne

Acupuncture for acute non-specific low back pain: a protocol for a randomised, controlled multicentre intervention study in general practice--the Acuback Study.

BMJ Open 2012;2(3). Epub 2012 jun 25

PMID: 22734119

Uhlig Till

Tai Chi and yoga as complementary therapies in rheumatologic conditions.

Best Pract Res Clin Rheumatol 2012 Jun;26(3):387-98.

PMID: 22867933

van Eijk-Hustings Yvonne, van Tubergen Astrid, Boström Carina, Braychenko Elena, Buss Beate, Felix José, Firth Jill, Hammond Alison, Harston Benny, Hernandez Cristina, Huzjak Masa, Korandová Jana, Kukkurainen Marja Leena, Landewé Robert, Mezieres Maryse, Milincovic Marijana, Moretti Antonella, Oliver Susan, Primdahl Jette, Scholte-Voshaar Marieke, de la Torre-Aboki Jenny, Waite-Jones Jennifer, Westhovens Rene, Zangi Heidi Andersen, Heiberg Turid, Hill Jackie, eUtils.ItemsChoiceType2[]

EULAR recommendations for the role of the nurse in the management of chronic inflammatory arthritis.

Ann Rheum Dis 2012 Jan;71(1):13-9. Epub 2011 okt 28

PMID: 22039168

Zangi Heidi A, Mowinckel Petter, Finset Arnstein, Eriksson Liv R, Høystad Turid Ø, Lunde Anne Kristine, Hagen Kåre B

A mindfulness-based group intervention to reduce psychological distress and fatigue in patients with inflammatory rheumatic joint diseases: a randomised controlled trial.

Ann Rheum Dis 2012 Jun;71(6):911-7. Epub 2011 des 20

PMID: 22186709

Berdal Gunnhild, Halvorsen Silje, van der Heijde Désirée, Mowe Morten, Dagfinrud Hanne

Restrictive pulmonary function is more prevalent in patients with ankylosing spondylitis than in matched population controls and is associated with impaired spinal mobility: a comparative study.

Arthritis Res Ther 2012;14(1):R19. Epub 2012 jan 25

PMID: 22277377

Dougados Maxime, Brault Yves, Logeart Isabelle, van der Heijde Désirée, Gossec Laure, Kvien Tore

Defining cut-off values for disease activity states and improvement scores for patient-reported outcomes: the example of the Rheumatoid Arthritis Impact of Disease (RAID).

Arthritis Res Ther 2012;14(3):R129. Epub 2012 mai 30

PMID: 22647431

Semb Anne Grete, Kvien Tore K, DeMicco David A, Fayyad Rana, Wun Chuan-Chuan, LaRosa John C, Betteridge John, Pedersen Terje R, Holme Ingar

Effect of intensive lipid-lowering therapy on cardiovascular outcome in patients with and those without inflammatory joint disease.

Arthritis Rheum 2012 Sep;64(9):2836-46.

PMID: 22576673

Haugen Ida Kristin, Bøyesen Pernille, Slatkowsky-Christensen Barbara, Sesseng Sølve, van der Heijde Désirée, Kvien Tore K

Associations between MRI-defined synovitis, bone marrow lesions and structural features and measures of pain and physical function in hand osteoarthritis.

Ann Rheum Dis 2012 Jun;71(6):899-904. Epub 2011 nov 25

PMID: 22121126

Lillegraven Siri, Prince Femke H M, Shadick Nancy A, Bykerk Vivian P, Lu Bing, Frits Michelle L, Iannaccone Christine K, Kvien Tore K, Haavardsholm Espen A, Weinblatt Michael E, Solomon Daniel H

Remission and radiographic outcome in rheumatoid arthritis: application of the 2011 ACR/EULAR remission criteria in an observational cohort.

Ann Rheum Dis 2012 May;71(5):681-6. Epub 2011 okt 12

PMID: 21994234

Haugen Ida K, Bøyesen Pernille, Slatkowsky-Christensen Barbara, Sesseng Sølve, Bijsterbosch Jessica, van der Heijde Désirée, Kvien Tore K

Comparison of features by MRI and radiographs of the interphalangeal finger joints in patients with hand osteoarthritis.

Ann Rheum Dis 2012 Mar;71(3):345-50. Epub 2011 okt 11

PMID: 21989543

Chatzidionysiou Katerina, Lie Elisabeth, Nasonov Evgeny, Lukina Galina, Hetland Merete Lund, Tarp Ulrik, van Riel Piet L C M, Nordström Dan C, Gomez-Reino Juan, Pavelka Karel, Tomsic Matija, Kvien Tore K, van Vollenhoven Ronald F, Gabay Cem

Effectiveness of disease-modifying antirheumatic drug co-therapy with methotrexate and leflunomide in rituximab-treated rheumatoid arthritis patients: results of a 1-year follow-up study from the CERERRA collaboration.

Ann Rheum Dis 2012 Mar;71(3):374-7. Epub 2011 okt 4

PMID: 21972242

Haavardsholm Espen A, Lie Elisabeth, Lillegraven Siri

Should modern imaging be part of remission criteria in rheumatoid arthritis?

Best Pract Res Clin Rheumatol 2012 Dec;26(6):767-85.

PMID: 23273791

Hammer Hilde Berner, Fagerhol Magne K, Wien Tale Norbye, Kvien Tore K

The soluble biomarker calprotectin (a S100 protein) is associated to ultrasonographic synovitis scores and is sensitive to change in patients with rheumatoid arthritis treated with adalimumab.

Arthritis Res Ther 2011 Oct;13(5):R178. Epub 2011 okt 26

PMID: 22029973

Martín Jose-Ezequiel, Alizadeh Behrooz Z, González-Gay Miguel A, Balsa Alejandro, Pascual-Salcedo Dora, González-Escribano María F, Rodriguez-Rodriguez Luis, Fernández-Gutiérrez Benjamín, Raya Enrique, Coenen Marieke J H, van Riel Piet, Radstake Timothy R D J, Kvien Tore K, Viken Marte K, Lie Benedicte A, Koeleman Bobby P C, Martín Javier

Evidence for PTPN22 R620W polymorphism as the sole common risk variant for rheumatoid arthritis in the 1p13.2 region.

J Rheumatol 2011 Nov;38(11):2290-6. Epub 2011 okt 1

PMID: 21965649

Mjaavatten Maria D, van der Heijde Désirée M, Uhlig Till, Haugen Anne J, Nygaard Halvor, Bjørneboe Olav, Kvien Tore K

Should anti-citrullinated protein antibody and rheumatoid factor status be reassessed during the first year of followup in recent-onset arthritis? A longitudinal study.

J Rheumatol 2011 Nov;38(11):2336-41. Epub 2011 okt 1

PMID: 21965645

Gandjbakhch Frédérique, Conaghan Philip G, Ejbjerg Bo, Haavardsholm Espen A, Foltz Violaine, Brown Andrew K, Møller Døhn Uffe, Lassere Marissa, Freeston Jane, Bøyesen Pernille, Bird Paul, Fautrel Bruno, Hetland Merete Lund, Emery Paul, Bourgeois Pierre, Hørslev-Petersen Kim, Kvien Tore K, McQueen Fiona, Ostergaard Mikkel

Synovitis and osteitis are very frequent in rheumatoid arthritis clinical remission: results from an MRI study of 294 patients in clinical remission or low disease activity state.

J Rheumatol 2011 Sep;38(9):2039-44.

PMID: 21885514

Maehlen Marthe T, Nordang Gry B, Syversen Silje W, van der Heijde Désirée M, Kvien Tore K, Uhlig Till, Lie Benedicte A

FCRL3 -169C/C genotype is associated with anti-citrullinated protein antibody-positive rheumatoid arthritis and with radiographic progression.

J Rheumatol 2011 Nov;38(11):2329-35. Epub 2011 sep 1

PMID: 21885492

Lie Elisabeth, van der Heijde Désirée, Uhlig Till, Mikkelsen Knut, Kalstad Synøve, Kaufmann Cecilie, Rødevand Erik, Kvien Tore K

Treatment strategies in patients with rheumatoid arthritis for whom methotrexate monotherapy has failed: data from the NOR-DMARD register.

Ann Rheum Dis 2011 Dec;70(12):2103-10. Epub 2011 aug 28

PMID: 21875874

Strand Vibeke, Boers Maarten, Idzerda Leanne, Kirwan John R, Kvien Tore K, Tugwell Peter S, Dougados Maxime

It's good to feel better but it's better to feel good and even better to feel good as soon as possible for as long as possible. Response criteria and the importance of change at OMERACT 10.

J Rheumatol 2011 Aug;38(8):1720-7.

PMID: 21807792

Haraoui Boulos, Smolen Josef S, Aletaha Daniel, Breedveld Ferdinand C, Burmester Gerd, Codreanu Catalin, Da Silva José Pereira, De Wit Maarten, Dougados Maxime, Durez Patrick, Emery Paul, Fonseca João Eurico, Gibofsky Allan, Gomez-Reino Juan, Graninger Winfried, Hamuryudan Vedat, Jannaut Peña Maria José, Kalden Joachim, Kvien Tore K, Laurindo Ieda, Martin-Mola Emilio, Montecucco Carlomaurizio, Santos Moreno Pedro, Pavelka Karel, Poor Gyula, Cardiel Mario H, Stanislawska-Biernat Ewa, Takeuchi Tsutomu, van der Heijde Désirée, PubMed.ItemsChoiceType2[]

Treating Rheumatoid Arthritis to Target: multinational recommendations assessment questionnaire.

Ann Rheum Dis 2011 Nov;70(11):1999-2002. Epub 2011 jul 29

PMID: 21803747

Scherer Hans Ulrich, van der Woude Diane, Willemze Annemiek, Trouw Leendert A, Knevel Rachel, Syversen Silje W, van der Linden Michael P M, Lie Benedicte, Huizinga Tom W J, van der Heijde Désirée M F M, van der Helm-van Mil Annette H M, Kvien Tore K, Toes René E M

Distinct ACPA fine specificities, formed under the influence of HLA shared epitope alleles, have no effect on radiographic joint damage in rheumatoid arthritis.

Ann Rheum Dis 2011 Aug;70(8):1461-4. Epub 2011 jun 10

PMID: 21666230

Wallenius Marianne, Skomsvoll Johan F, Irgens Lorentz M, Salvesen Kjell Å, Nordvåg Bjorn Y, Koldingsnes Wenche, Mikkelsen Knut, Kaufmann Cecilie, Kvien Tore K

Pregnancy and delivery in women with chronic inflammatory arthritides with a specific focus on first birth.

Arthritis Rheum 2011 Jun;63(6):1534-42.

PMID: 21630243

Haugen Ida K, Englund Martin, Aliabadi Piran, Niu Jingbo, Clancy Margaret, Kvien Tore K, Felson David T

Prevalence, incidence and progression of hand osteoarthritis in the general population: the Framingham Osteoarthritis Study.

Ann Rheum Dis 2011 Sep;70(9):1581-6. Epub 2011 mai 27

PMID: 21622766

Hammer Hilde Berner, Kvien Tore K

Comparisons of 7- to 78-joint ultrasonography scores: all different joint combinations show equal response to adalimumab treatment in patients with rheumatoid arthritis.

Arthritis Res Ther 2011;13(3):R78. Epub 2011 mai 27

PMID: 21619619

Chatzidionysiou Katerina, Lie Elisabeth, Nasonov Evgeny, Lukina Galina, Hetland Merete Lund, Tarp Ulrik, Gabay Cem, van Riel Piet L C M, Nordström Dan C, Gomez-Reino Juan, Pavelka Karel, Tomsic Matija, Kvien Tore K, van Vollenhoven Ronald F

Highest clinical effectiveness of rituximab in autoantibody-positive patients with rheumatoid arthritis and in those for whom no more than one previous TNF antagonist has failed: pooled data from 10 European registries.

Ann Rheum Dis 2011 Sep;70(9):1575-80. Epub 2011 mai 12

PMID: 21571731

Bijsterbosch J, Haugen I K, Malines C, Maheu E, Rosendaal F R, Watt I, Berenbaum F, Kvien T K, van der Heijde D M, Huizinga T W J, Kloppenburg M

Reliability, sensitivity to change and feasibility of three radiographic scoring methods for hand osteoarthritis.

Ann Rheum Dis 2011 Aug;70(8):1465-7. Epub 2011 mai 10

PMID: 21558294

Gossec L, Paternotte S, Aanerud G J, Balanescu A, Boumpas D T, Carmona L, de Wit M, Dijkmans B A C, Dougados M, Englbrecht M, Gogus F, Heiberg T, Hernandez C, Kirwan J R, Mola E Martin, Cerinic M Matucci, Otsa K, Schett G, Scholte-Voshaar M, Sokka T, Von Krause G, Wells G A, Kvien T K

Finalisation and validation of the rheumatoid arthritis impact of disease score, a patient-derived composite measure of impact of rheumatoid arthritis: a EULAR initiative.

Ann Rheum Dis 2011 Jun;70(6):935-42.

PMID: 21540201

Braun J, van den Berg R, Baraliakos X, Boehm H, Burgos-Vargas R, Collantes-Estevez E, Dagfinrud H, Dijkmans B, Dougados M, Emery P, Geher P, Hammoudeh M, Inman R D, Jongkees M, Khan M A, Kiltz U, Kvien TK, Leirisalo-Repo M, Maksymowych W P, Olivieri I, Pavelka K, Sieper J, Stanislawska-Biernat E, Wendling D, Ozgocmen S, van Drogen C, van Royen BJ, van der Heijde D

2010 update of the ASAS/EULAR recommendations for the management of ankylosing spondylitis.

Ann Rheum Dis 2011 Jun;70(6):896-904.

PMID: 21540199

van der Linden M P M, Batstra M R, Bakker-Jonges L E, PubMed.ItemsChoiceType2[], Detert J, Bastian H, Scherer H U, Toes R E M, Burmester G-R, Mjaavatten M D, Kvien T K, Huizinga T W J, van der Helm-van Mil A H M

Toward a data-driven evaluation of the 2010 American College of Rheumatology/European League Against Rheumatism criteria for rheumatoid arthritis: is it sensible to look at levels of rheumatoid factor?

Arthritis Rheum 2011 May;63(5):1190-9.

PMID: 21538311

Lillegraven Siri, Bøyesen Pernille, Hammer Hilde Berner, Østergaard Mikkel, Uhlig Till, Sesseng Sølve, Kvien Tore K, Haavardsholm Espen A

Tenosynovitis of the extensor carpi ulnaris tendon predicts erosive progression in early rheumatoid arthritis.

Ann Rheum Dis 2011 Nov;70(11):2049-50. Epub 2011 apr 24

PMID: 21515919

Dagfinrud Hanne, Halvorsen Silje, Vøllestad Nina K, Niedermann Karin, Kvien Tore K, Hagen Kåre B

Exercise programs in trials for patients with ankylosing spondylitis: do they really have the potential for effectiveness?

Arthritis Care Res (Hoboken) 2011 Apr;63(4):597-603.

PMID: 21452270

Haugen Ida K, Lillegraven Siri, Slatkowsky-Christensen Barbara, Haavardsholm Espen A, Sesseng Sølve, Kvien Tore K, van der Heijde Désirée, Bøyesen Pernille

Hand osteoarthritis and MRI: development and first validation step of the proposed Oslo Hand Osteoarthritis MRI score.

Ann Rheum Dis 2011 Jun;70(6):1033-8. Epub 2011 mar 24

PMID: 21436160

Haugen Ida Kristin, Moe Rikke Helene, Slatkowsky-Christensen Barbara, Kvien Tore Kristian, van der Heijde Désirée, Garratt Andrew

The AUSCAN subscales, AIMS-2 hand/finger subscale, and FIOHA were not unidimensional scales.

J Clin Epidemiol 2011 Sep;64(9):1039-46. Epub 2011 mar 16

PMID: 21411282

Heiberg Turid, Austad Cathrine, Kvien Tore K, Uhlig Till

Performance of the Rheumatoid Arthritis Impact of Disease (RAID) score in relation to other patient-reported outcomes in a register of patients with rheumatoid arthritis.

Ann Rheum Dis 2011 Jun;70(6):1080-2. Epub 2011 mar 6

PMID: 21378406

Buch Maya H, Smolen Josef S, Betteridge Neil, Breedveld Ferdinand C, Burmester Gerd, Dörner Thomas, Ferraccioli Gianfranco, Gottenberg Jacques-Eric, Isaacs John, Kvien Tore K, Mariette Xavier, Martin-Mola Emilio, Pavelka Karel, Tak Paul P, van der Heijde Desiree, van Vollenhoven Ronald F, Emery Paul, PubMed.ItemsChoiceType2[]

Updated consensus statement on the use of rituximab in patients with rheumatoid arthritis.

Ann Rheum Dis 2011 Jun;70(6):909-20. Epub 2011 mar 6

PMID: 21378402

Grandaunet Berit, Syversen Silje W, Hoff Mari, Sundan Anders, Haugeberg Glenn, van der Heijde Desirée, Kvien Tore K, Standal Therese

Association between high plasma levels of hepatocyte growth factor and progression of radiographic damage in the joints of patients with rheumatoid arthritis.

Arthritis Rheum 2011 Mar;63(3):662-9.

PMID: 21360495

Hoff Mari, Kvien Tore K, Kälvesten Johan, Elden Aake, Kavanaugh Arthur, Haugeberg Glenn

Adalimumab reduces hand bone loss in rheumatoid arthritis independent of clinical response: subanalysis of the PREMIER study.

BMC Musculoskelet Disord 2011;12():54. Epub 2011 feb 27

PMID: 21352592

Felson David T, Smolen Josef S, Wells George, Zhang Bin, van Tuyl Lilian H D, Funovits Julia, Aletaha Daniel, Allaart Cornelia F, Bathon Joan, Bombardieri Stefano, Brooks Peter, Brown Andrew, Matucci-Cerinic Marco, Choi Hyon, Combe Bernard, De Wit Maarten, Dougados Maxime, Emery Paul, Furst Daniel, Gomez-Reino Juan, Hawker Gillian, Keystone Edward, Khanna Dinesh, Kirwan John, Kvien Tore K, Landewé Robert, Listing Joachim, Michaud Kaleb, Martin-Mola Emilio, Montie Pamela, Pincus Theodore, Richards Pamela, Siegel Jeffrey N, Simon Lee S, Sokka Tuulikki, Strand Vibeke, Tugwell Peter, Tyndall Alan, van der Heijde Desirée, Verstappen Suzan, White Barbara, Wolfe Frederick, Zink Angela, Boers Maarten, PubMed.ItemsChoiceType2[], PubMed.ItemsChoiceType2[]

American College of Rheumatology/European League Against Rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials.

Arthritis Rheum 2011 Mar;63(3):573-86.

PMID: 21294106

American College of Rheumatology/European League against Rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials.

Ann Rheum Dis 2011 Mar;70(3):404-13.

PMID: 21292833

Wallenius Marianne, Skomsvoll Johan F, Irgens Lorentz M, Salvesen Kjell Å, Nordvåg Bjorn-Yngvar, Koldingsnes Wenche, Mikkelsen Knut, Kaufmann Cecilie, Kvien Tore K

Fertility in women with chronic inflammatory arthritides.

Rheumatology (Oxford) 2011 Jun;50(6):1162-7. Epub 2011 feb 3

PMID: 21292737

Provan Sella A, Semb Anne Grete, Hisdal Jonny, Stranden Einar, Agewall Stefan, Dagfinrud Hanne, Angel Kristin, Atar Dan, Kvien Tore K

Remission is the goal for cardiovascular risk management in patients with rheumatoid arthritis: a cross-sectional comparative study.

Ann Rheum Dis 2011 May;70(5):812-7. Epub 2011 feb 2

PMID: 21288959

Osnes-Ringen H, Kvamme M K, Kristiansen I S, Thingstad M, Henriksen J E, Kvien T K, Dagfinrud H

Cost-effectiveness analyses of elective orthopaedic surgical procedures in patients with inflammatory arthropathies.

Scand J Rheumatol 2011 Mar;40(2):108-15. Epub 2011 jan 17

PMID: 21241197

Provan Sella A, Angel Kristin, Semb Anne Grete, Mowinckel Petter, Agewall Stefan, Atar Dan, Kvien Tore K

Early prediction of increased arterial stiffness in patients with chronic inflammation: a 15-year followup study of 108 patients with rheumatoid arthritis.

J Rheumatol 2011 Apr;38(4):606-12. Epub 2011 jan 15

PMID: 21239744

Vis M, Haavardsholm E A, Bøyesen P, Haugeberg G, Uhlig T, Hoff M, Woolf A, Dijkmans B, Lems W, Kvien T K

High incidence of vertebral and non-vertebral fractures in the OSTRA cohort study: a 5-year follow-up study in postmenopausal women with rheumatoid arthritis.

Osteoporos Int 2011 Sep;22(9):2413-9. Epub 2011 jan 13

PMID: 21229234

Helland Ylva, Kjeken Ingvild, Steen Eldri, Kvien Tore K, Hauge Mona-Iren, Dagfinrud Hanne

Rheumatic diseases and sexuality: Disease impact and self-management strategies.

Arthritis Care Res (Hoboken) 2011 May;63(5):743-50.

PMID: 21225671

Hammer Hilde Berner, Bolton-King Pernille, Bakkeheim Vivi, Berg Torill Helene, Sundt Elisabeth, Kongtorp Anne Katrine, Haavardsholm Espen A

Examination of intra and interrater reliability with a new ultrasonographic reference atlas for scoring of synovitis in patients with rheumatoid arthritis.

Ann Rheum Dis 2011 Nov;70(11):1995-8. Epub 2011 jul 22

PMID: 21784724

Conaghan Philip G, McQueen Fiona M, Bird Paul, Peterfy Charles G, Haavardsholm Espen A, Gandjbakhch Frédérique, Bøyesen Pernille, Coates Laura, Ejbjerg Bo, Eshed Iris, Foltz Violaine, Hermann Kay-Geert, Freeston Jane, Lillegraven Siri, Lassere Marissa, Wiell Charlotte, Anandarajah Allen, Duer-Jensen Anne, O'Connor Philip, Genant Harry K, Emery Paul, Ostergaard Mikkel

Update on research and future directions of the OMERACT MRI inflammatory arthritis group.

J Rheumatol 2011 Sep;38(9):2031-3.

PMID: 21885512

Bøyesen Pernille, McQueen Fiona M, Gandjbakhch Frédérique, Lillegraven Siri, Coates Laura, Wiell Charlotte, Haavardsholm Espen A, Conaghan Philip G, Peterfy Charles G, Bird Paul, Ostergaard Mikkel

The OMERACT Psoriatic Arthritis Magnetic Resonance Imaging Score (PsAMRIS) is reliable and sensitive to change: results from an OMERACT workshop.

J Rheumatol 2011 Sep;38(9):2034-8.

PMID: 21885513

Ostergaard Mikkel, Bøyesen Pernille, Eshed Iris, Gandjbakhch Frédérique, Lillegraven Siri, Bird Paul, Foltz Violaine, Boonen Annelies, Lassere Marissa, Hermann Kay-Geert, Anandarajah Allen, Døhn Uffe Møller, Freeston Jane, Peterfy Charles G, Genant Harry K, Haavardsholm Espen A, McQueen Fiona M, Conaghan Philip G

Development and preliminary validation of a magnetic resonance imaging joint space narrowing score for use in rheumatoid arthritis: potential adjunct to the OMERACT RA MRI scoring system.

J Rheumatol 2011 Sep;38(9):2045-50.

PMID: 21885515

Moe Rikke H, Haavardsholm Espen A, Grotle Margreth, Steen Eldri, Kjeken Ingvild, Hagen Kåre Birger, Uhlig Till

Development of a brief multidisciplinary education programme for patients with osteoarthritis.

BMC Musculoskelet Disord 2011;12():257. Epub 2011 nov 11

PMID: 22077985

Haugen Ida K, Bøyesen Pernille

Imaging modalities in hand osteoarthritis - status and perspectives of conventional radiography, magnetic resonance imaging, and ultrasonography.

Arthritis Res Ther 2011 Dec;13(6):248. Epub 2011 des 13

PMID: 22189142

Haugen Ida K, Niu Jingbo, Aliabadi Piran, Felson David T, Englund Martin

The associations between finger length pattern, osteoarthritis, and knee injury: data from the Framingham community cohort.

Arthritis Rheum 2011 Aug;63(8):2284-8.

PMID: 21506096

Halvorsen E H, Strønen E, Hammer H B, Goll G L, Sollid L M, Molberg O

Interleukin-15 induces interleukin-17 production by synovial T cell lines from patients with rheumatoid arthritis.

Scand J Immunol 2011 Mar;73(3):243-9.

PMID: 21204897

Grotle Margreth, Hagen Kåre Birger, Uhlig Till, Aas Eline

Cost of illness for patients with arthritis receiving multidisciplinary rehabilitation care.

Rehabil Res Pract 2011;2011():487025. Epub 2011 jul 26

PMID: 22110975

Kjeken Ingvild, Smedslund Geir, Moe Rikke H, Slatkowsky-Christensen Barbara, Uhlig Till, Hagen Kåre Birger

Systematic review of design and effects of splints and exercise programs in hand osteoarthritis.

Arthritis Care Res (Hoboken) 2011 Jun;63(6):834-48.

PMID: 21630479

Zhang W, Doherty M, Pascual E, Barskova V, Guerne P-A, Jansen T L, Leeb B F, Perez-Ruiz F, Pimentao J, Punzi L, Richette P, Sivera F, Uhlig T, Watt I, Bardin T

EULAR recommendations for calcium pyrophosphate deposition. Part II: management.

Ann Rheum Dis 2011 Apr;70(4):571-5. Epub 2011 jan 20

PMID: 21257614

Zhang W, Doherty M, Bardin T, Barskova V, Guerne P-A, Jansen T L, Leeb B F, Perez-Ruiz F, Pimentao J, Punzi L, Richette P, Sivera F, Uhlig T, Watt I, Pascual E

European League Against Rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis.

Ann Rheum Dis 2011 Apr;70(4):563-70. Epub 2011 jan 7

PMID: 21216817

Hazlewood Glen, Aletaha Daniel, Carmona Loreto, Landewé Robert B M, van der Heijde Désirée M, Bijlsma Johannes W J, Bykerk Vivian P, Canhão Helena, Catrina Anca I, Durez Patrick, Edwards Christopher J, Leeb Burkhard F, Mjaavatten Maria D, Martinez-Osuna Pindaro, Montecucco Carlomaurizio, Ostergaard Mikkel, Serra-Bonett Natali, Xavier Ricardo M, Zochling Jane, Machado Pedro, Thevissen Kristof, Vercoutere Ward, Bombardier Claire

Algorithm for identification of undifferentiated peripheral inflammatory arthritis: a multinational collaboration through the 3e initiative.

J Rheumatol Suppl 2011 Mar;87():54-8.

PMID: 21364058

Christie Anne, Dagfinrud Hanne, Garratt Andrew M, Ringen Osnes Hanne, Hagen Kåre Birger

Identification of shoulder-specific patient acceptable symptom state in patients with rheumatic diseases undergoing shoulder surgery.

J Hand Ther 2011 Jan-Mar;24(1):53-60; quiz 61.

PMID: 21272764

Christie Anne, Dagfinrud Hanne, Ringen Hanne O, Hagen Kåre Birger

Beneficial and harmful effects of shoulder arthroplasty in patients with rheumatoid arthritis: results from a Cochrane review.

Rheumatology (Oxford) 2011 Mar;50(3):598-602. Epub 2010 nov 23

PMID: 21098575

Machado P, Castrejon I, Katchamart W, Koevoets R, Kuriya B, Schoels M, Silva-Fernández L, Thevissen K, Vercoutere W, Villeneuve E, Aletaha D, Carmona L, Landewé R, van der Heijde D, Bijlsma J W J, Bykerk V, Canhão H, Catrina A I, Durez P, Edwards C J, Mjaavatten M D, Leeb B F, Losada B, Martín-Mola E M, Martinez-Osuna P, Montecucco C, Müller-Ladner U, Østergaard M, Sheane B, Xavier R M, Zochling J, Bombardier C

Multinational evidence-based recommendations on how to investigate and follow-up undifferentiated peripheral inflammatory arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative.

Ann Rheum Dis 2011 Jan;70(1):15-24. Epub 2010 aug 19

PMID: 20724311

Graugaard Peter Kjær, Rogg Lotte, Eide Hilde, Uhlig Till, Loge Jon Håvard

Ways of providing the patient with a prognosis: a terminology of employed strategies based on qualitative data.

Patient Educ Couns 2011 Apr;83(1):80-6. Epub 2010 jun 8

PMID: 20570463

Reinseth Lillian, Uhlig Till, Kjeken Ingvild, Koksvik Hege Svean, Skomsvoll Johan Fredrik, Espnes Geir Arild

Performance in leisure-time physical activities and self-efficacy in females with rheumatoid arthritis.

Scand J Occup Ther 2011 Sep;18(3):210-8. Epub 2010 sep 23

PMID: 20863170

Gossec L, Bijlsma J W J, Bombardier C, Canhão H, Devlin J, Edwards C J, Hamuryudan V, Kvien T K, Leeb B F, Martín-Mola E M, Mielants H, Müller-Ladner U, Ostergaard M, Pereira I A, Ramos-Remus C, Zochling J, Dougados Maxime

Dissemination and evaluation of the 3E initiative recommendations for use of methotrexate in rheumatic disorders: results of a study among 2233 rheumatologists.

Ann Rheum Dis 2011 Feb;70(2):388-9. Epub 2010 mai 14

PMID: 20472594

Bøyesen Pernille, Haavardsholm Espen A, Ostergaard Mikkel, van der Heijde Désirée, Sesseng Sølve, Kvien Tore K

MRI in early rheumatoid arthritis: synovitis and bone marrow oedema are independent predictors of subsequent radiographic progression.

Ann Rheum Dis 2011 Mar;70(3):428-33. Epub 2010 aug 31

PMID: 20810395

Angel Kristin, Provan Sella Aarrestad, Hammer Hilde Berner, Mowinckel Petter, Kvien Tore Kristian, Atar Dan

Changes in arterial stiffness during continued infliximab treatment in patients with inflammatory arthropathies.

Fundam Clin Pharmacol 2011 Aug;25(4):511-7. Epub 2010 sep 6

PMID: 20825487

Semb Anne G, Holme Ingar, Kvien Tore K, Pedersen Terje R

Intensive lipid lowering in patients with rheumatoid arthritis and previous myocardial infarction: an explorative analysis from the incremental decrease in endpoints through aggressive lipid lowering (IDEAL) trial.

Rheumatology (Oxford) 2011 Feb;50(2):324-9. Epub 2010 sep 30

PMID: 20884656

Lie E, van der Heijde D, Uhlig T, Mikkelsen K, Rødevand E, Koldingsnes W, Kaufmann C, Kvien T K

Effectiveness of switching between TNF inhibitors in ankylosing spondylitis: data from the NOR-DMARD register.

Ann Rheum Dis 2011 Jan;70(1):157-63. Epub 2010 nov 9

PMID: 21062852

Bøyesen Pernille, Haavardsholm Espen A, van der Heijde Désirée, Østergaard Mikkel, Hammer Hilde Berner, Sesseng Sølve, Kvien Tore K

Prediction of MRI erosive progression: a comparison of modern imaging modalities in early rheumatoid arthritis patients.

Ann Rheum Dis 2011 Jan;70(1):176-9. Epub 2010 nov 10

PMID: 21068093

Machado Pedro, Landewé Robert, Lie Elisabeth, Kvien Tore K, Braun Jürgen, Baker Daniel, van der Heijde Désirée, PubMed.ItemsChoiceType2[]

Ankylosing Spondylitis Disease Activity Score (ASDAS): defining cut-off values for disease activity states and improvement scores.

Ann Rheum Dis 2011 Jan;70(1):47-53. Epub 2010 nov 10

PMID: 21068095

Hammer H B, Kvien T K

Ultrasonography shows significant improvement in wrist and ankle tenosynovitis in rheumatoid arthritis patients treated with adalimumab.

Scand J Rheumatol 2011 May;40(3):178-82. Epub 2010 nov 23

PMID: 21091275

Heiberg Turid, Lie Elisabeth, van der Heijde Désirée, Kvien Tore K

Sleep problems are of higher priority for improvement for patients with ankylosing spondylitis than for patients with other inflammatory arthropathies.

Ann Rheum Dis 2011 May;70(5):872-3. Epub 2010 nov 24

PMID: 21109522

Doktorgrader

Ylva Helland

Sexuality and rheumatic diseases

Disputert:: november 2013
Hovedveileder:: Hanne Solveig Dagfinrud

Rikke Helene Moe

Function in patients with osteoarthritis

Disputert:: april 2013
Hovedveileder:: Tillmann Uhlig

Mari Klokkerud

Rehabilitation for patients with rheumatic diseases. Describing the content and measuring outcomes.

Disputert:: desember 2013
Hovedveileder:: Margreth Grotle

Siri Lillegraven

Joint damage in rheumatoid arthritis

Disputert:: november 2013
Hovedveileder:: Espen Andre Haavardsholm

Elisabeth Lie

Effectivness of synthetic and biological disease modifying antirheumatic drugs in patients with inflammatory joint diseases. Res

Disputert:: januar 2012
Hovedveileder:: Tore K Kvien

Ida Kristin Haugen

The Reliability and Validity of MRI in hand osteoarthritis

Disputert:: april 2012
Hovedveileder:: Tore K Kvien

Mari Dahl Mjaavatten

Disease characteristics, predictors and outcomes in patients with very early arthritis

Disputert:: oktober 2012
Hovedveileder:: Tore K Kvien

Heidi Andersen Zangi

Vitality Training - a group -based intervention for persons with rheumatic diseases. Experiences, methodological aspects and cli

Disputert:: august 2012
Hovedveileder:: Kåre Birger Hagen

Barbara Slatkowsky-Christensen

Symptoms, Functional Aspects and Health Related Quality of Life in Patients with Hand Osteoarthritis

Disputert:: januar 2011
Hovedveileder:: Tore K Kvien

Anne Christie

Measuring outcomes of shoulder surgery in patients with rheumatic diseases

Disputert:: april 2011
Hovedveileder:: Kåre Birger Hagen

Sella Aarrestad Provan

Predictors of cardiovascular disease in rheumatoid arthritis

Disputert:: august 2011
Hovedveileder:: Tore K Kvien

Deltagere

Tore Kristian Kvien Forskningsgruppeleder

eRapport er utarbeidet av Sølvi Lerfald og Reidar Thorstensen, Regionalt kompetansesenter for klinisk forskning, Helse Vest RHF, og videreutvikles av de fire RHF-ene i fellesskap, med støtte fra Helse Vest IKT

Alle henvendelser rettes til eRapport

Personvern - Informasjonskapsler